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1. Chronic Severe Pain
Long-term management of conditions where daily, round-the-clock opioid treatment is necessary.
Example: Chronic low back pain, severe osteoarthritis, or post-surgical chronic pain.
2. Neuropathic Pain
Especially in cases like:
Diabetic peripheral neuropathy
Nerve compression syndromes (sciatica, spinal nerve root pain)
3. Cancer-Related Pain
Used in palliative care when pain is persistent and intense.
💊 Formulation:
Usually in Extended-Release (ER) tablets
Provides 12–24 hour pain relief
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