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Alpha-1 adrenergic blocker or alpha-blocker

Generic Name: Silodosin Strength: 8 mg per capsule Dosage Form: Hard gelatin capsule Therapeutic Class: Urology / Alpha-1 adrenergic blocker Mechanism of Action: Silodosin is a selective alpha-1A receptor antagonist. It relaxes smooth muscles in the prostate, bladder neck, and urethra, improving urine flow and easing symptoms of urinary difficulty. Prescription Status: Prescription-only medicine (used under doctor supervision) Inactive Ingredients: (May vary by manufacturer; typical excipients include capsule shell and fillers — refer to packaging.) Storage: Store in a cool, dry place below 30 °C. Keep out of reach of children. Sildoease 8mg capsules (containing silodosin) are primarily used to treat symptoms of an enlarged prostate, known as Benign Prostatic Hyperplasia (BPH). They work by relaxing the muscles in the prostate and bladder neck, facilitating better urine flow, reducing frequent or urgent urination, and easing difficulties initiating urination. Key Uses of Sildoease 8: Benign Prostatic Hyperplasia (BPH) Treatment: Relieves symptoms such as weak stream, straining, dribbling, and incomplete bladder emptying. Urinary Urgency and Frequency Reduction: Decreases the need to urinate frequently, especially during the night (nocturia). Relaxation of Urinary Tract Muscles: Reduces muscle tension in the bladder and prostate for improved flow. Preventing Urinary Blockage: Helps prevent complete, acute urinary retention caused by an enlarged prostate. Pharmacological Notes : Silodosin targets alpha-1A adrenergic receptors predominantly found in the prostate and urethral tissues, helping to alleviate lower urinary tract symptoms with relative selectivity compared to non-selective alpha-blockers. SILDOEASE 8 mg is used to treat urinary problems caused by an enlarged prostate. Main Uses : Benign Prostatic Hyperplasia (BPH) Difficulty in passing urine Weak or interrupted urine flow Frequent urination, especially at night (nocturia) Urgent need to urinate Incomplete bladder emptying 💡 How it Helps Relaxes muscles of the prostate and bladder neck Improves urine flow Reduces straining and discomfort while urinating

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Anti-Hemorrhoidal or Anal Fissure treatment agent

Brand Name: Anovate Cream / Ointment 20 gm Dosage Form: Topical cream/ointment for external and rectal application Strength / Composition: Per gram of cream/ointment: • Beclomethasone (0.025 % w/w) — a corticosteroid that reduces inflammation and itching • Phenylephrine Hydrochloride (0.1 % w/w) — a vasoconstrictor that helps shrink swollen blood vessels • Lidocaine / Lignocaine Hydrochloride (2.5 % w/w) — a local anesthetic that numbs pain and irritation Mechanism of Action Beclomethasone: Reduces inflammatory chemicals in the affected area. Phenylephrine: Constricts blood vessels → decreases swelling and bleeding. Lidocaine: Blocks pain signal transmission from local nerves → rapid pain relief. Packaging & Storage Comes in a 20 gm tube. Store at room temperature, protected from heat and moisture. Keep out of reach of children. Anovate Ointment (20gm) is a combination medication used to treat pain, swelling, itching, and bleeding associated with hemorrhoids (piles), anal fissures, and proctitis. It reduces inflammation, constricts blood vessels, and provides a numbing effect for rapid relief. It is for external anal use only. Key Uses of Anovate Ointment: Hemorrhoids (Piles): Relieves pain, swelling, and itching associated with internal and external piles. Anal Fissures: Helps soothe and heal small tears in the anal lining. Proctitis: Manages inflammation of the rectal lining. Post-Surgery Care: Used for pain relief and healing after hemorrhoidectomy or anal procedures. ANOVATE ointment is used for anorectal conditions where there is pain, swelling, itching, or inflammation. Main Uses : Hemorrhoids (piles) – internal and external Anal fissures (small tears in the anal lining) Pain, burning, and itching around the anal area Swelling and bleeding associated with piles Inflammation of the anal canal How it Helps : Relieves pain and itching (lidocaine) Reduces swelling and bleeding (phenylephrine) Controls inflammation and irritation (beclomethasone)

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Pain Killer Medicines

Active Ingredient: Celecoxib 200 mg per capsule/tablet — a selective cyclo-oxygenase-2 (COX-2) inhibitor, which helps reduce pain and inflammation. Dosage Form: Oral hard capsule (white capsule with gold bands marked 7767 and 200 in some formulations). Pharmacological Class: NSAID (Coxib subclass) — selective COX-2 inhibitor. Mechanism of Action: Reduces synthesis of prostaglandins by selectively inhibiting the COX-2 enzyme, thereby decreasing pain, inflammation, and swelling with relatively less effect on COX-1. Inactive Ingredients (may vary by manufacturer): Lactose monohydrate Croscarmellose sodium Povidone Magnesium stearate Sodium lauryl sulfate Gelatin and capsule shell components (e.g., titanium dioxide) Celebrex 200 mg (active ingredient: celecoxib) is a non-steroidal anti-inflammatory drug (NSAID) classified as a selective COX-2 inhibitor. It is primarily used to treat pain and inflammation caused by osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain, and menstrual pain. It acts by blocking COX-2 enzymes. Key Details About Celebrex 200 mg: Drug Category: NSAID (Non-steroidal Anti-inflammatory Drug), specifically a COX-2 Inhibitor. Uses: Relieves joint stiffness, pain, and swelling (arthritis), menstrual pain, and acute injuries. Mechanism: It works by inhibiting the COX-2 enzyme, which reduces the production of prostaglandins, chemical messengers responsible for pain and inflammation. Safety Notice: While it is often less harsh on the stomach than traditional NSAIDs, it still carries risks for cardiovascular events (heart attack/stroke) and gastrointestinal bleeding. Dosage: Generally taken once or twice daily, as prescribed by a doctor. General Therapeutic Uses : (These overlap with its specification-related purpose — mainly relief of pain and inflammation.) CELEBREX 200 mg is indicated for: Relief of symptoms in osteoarthritis (joint pain and stiffness). Relief of symptoms in rheumatoid arthritis. Relief of symptoms in ankylosing spondylitis (pain/stiffness of the spine). Management of acute pain (as part of doctor-directed use). May be used for primary dysmenorrhea (menstrual pain) and other inflammatory pain as advised by a physician.

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