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Sorafeshield Sorafenib Tablets IP 200 mg | Sorafenib 200 mg | Anticancer Targeted Therapy Medicine |
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Sorafeshield contains sorafenib 200 mg, an oral multikinase inhibitor used in the treatment of certain cancers. Sorafenib works by inhibiting multiple protein kinases involved in tumour-cell growth, proliferation and the formation of new blood vessels that can support tumour growth.
Sorafenib is used in approved clinical settings for certain patients with unresectable hepatocellular carcinoma, advanced renal cell carcinoma and differentiated thyroid carcinoma that is refractory to radioactive iodine treatment, depending on applicable product labeling and clinical guidelines.
Treatment should be initiated and monitored by an experienced oncology professional. Regular monitoring may include blood pressure, liver function, blood counts, electrolyte levels and other clinically appropriate parameters.
20 FAQs - Sorafeshield Sorafenib Tablets IP 200 mg
What is Sorafeshield Sorafenib 200 mg?
Sorafeshield contains sorafenib, an oral kinase inhibitor used in the treatment of certain cancers.
What is Sorafenib 200 mg used for?
U.S. labeling includes unresectable hepatocellular carcinoma, advanced renal cell carcinoma, and certain differentiated thyroid cancers refractory to radioactive iodine.
How does sorafenib work?
Sorafenib inhibits multiple protein kinases involved in tumor-cell growth and blood-vessel formation.
What is the strength of Sorafeshield?
The product is listed as sorafenib 200 mg tablets.
How is Sorafenib 200 mg taken?
The U.S. prescribing information specifies oral administration without food; the treating oncologist determines the appropriate regimen.
Is Sorafeshield a prescription medicine?
Yes. Sorafenib is a prescription oncology medicine requiring medical supervision.
Can sorafenib be used for liver cancer?
Sorafenib is indicated for certain patients with unresectable hepatocellular carcinoma.
Can sorafenib be used for kidney cancer?
U.S. labeling includes advanced renal cell carcinoma for certain sorafenib products.
Can sorafenib be used for thyroid cancer?
It is indicated for locally recurrent or metastatic, progressive differentiated thyroid carcinoma that is refractory to radioactive iodine treatment.
What are common adverse effects of sorafenib?
Reported effects include diarrhea, fatigue, rash, hand-foot skin reaction, decreased appetite, nausea, hypertension and hair loss.
Can sorafenib cause high blood pressure?
Yes. Blood pressure should be monitored during treatment, particularly during the initial weeks.
Can sorafenib cause hand-foot skin reactions?
Yes. Dermatologic toxicities, including hand-foot skin reaction, are recognized adverse effects and may require treatment adjustment.
Does sorafenib affect wound healing?
Sorafenib can impair wound healing, and the prescribing information provides recommendations regarding interruption around major surgery.
Can sorafenib interact with other medicines?
Yes. Drug interactions can occur, including with strong CYP3A4 inducers and certain medicines affecting bleeding or cardiac rhythm.
Can sorafenib be used during pregnancy?
Sorafenib may cause fetal harm. Pregnancy and contraception considerations should be discussed with the treating healthcare professional.
Can breastfeeding continue during sorafenib treatment?
U.S. labeling advises women not to breastfeed during treatment and for the specified period after the final dose.
Does sorafenib require regular monitoring?
Yes. Depending on the patient, monitoring may include blood pressure, liver function, blood counts, electrolytes and other clinically appropriate parameters.
Can Sorafeshield 200 mg be used without an oncologist's supervision?
No. Treatment should be prescribed and monitored by an appropriately qualified healthcare professional.
How should Sorafeshield Sorafenib 200 mg be stored?
Store according to the manufacturer's approved packaging and product information.
Can I request a quotation for Sorafeshield Sorafenib 200 mg?
For legitimate institutional or pharmaceutical supply, quotation requirements generally include the required quantity, destination and applicable regulatory documentation.
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