Product Name: Ruxolitinib Cream (commonly marketed as Rutinib Cream 1.5%)
Form: Topical cream for skin application
Strength/Concentration: 1.5% w/w ruxolitinib (active ingredient)
Composition :
Active Ingredient:
• Ruxolitinib 1.5% w/w — a Janus kinase (JAK1/JAK2) inhibitor that modulates inflammatory and immune signaling in the skin.
Mechanism of Action :
Ruxolitinib blocks JAK enzymes involved in immune signaling (JAK1 and JAK2). This reduces inflammation, modulates immune responses in the skin, and helps control inflammatory and pigmentary processes.
Indications / Uses :
This cream is used (on medical prescription) for the topical treatment of:
Atopic dermatitis (eczema) — especially mild to moderate cases not adequately controlled by other topical therapies.
Non-segmental vitiligo — to help promote repigmentation of depigmented skin patches in patients aged 12 years and older.
Application & Administration :
Apply a thin layer directly to affected skin areas as directed by your healthcare provider.
Typically used twice daily on clean, dry skin, usually up to a limited body surface area.
Avoid contact with eyes and mucous membranes.
Rutinib cream contains ruxolitinib, a topical JAK (Janus kinase) inhibitor used to treat certain inflammatory and autoimmune skin conditions.
Key Uses and Indications :
Atopic Dermatitis (Eczema): Treats red, irritated, and itchy skin in patients with mild to moderate eczema.
Vitiligo: Used for nonsegmental vitiligo in patients 12 and older, aiding in repigmentation of the skin.
Mechanism of Action: As a Janus kinase (JAK) inhibitor, it works by suppressing immune responses in the skin to reduce inflammation.
Rutinib Cream 1.5% (containing Ruxolitinib) is a prescription topical JAK inhibitor used for the short-term treatment of mild-to-moderate eczema (atopic dermatitis) and nonsegmental vitiligo in adults and children 12 years and older. It reduces itching, inflammation, and helps restore skin pigmentation.
How It Works :
Ruxolitinib blocks JAK1 and JAK2 enzymes, which are involved in inflammatory and immune signaling pathways.
This helps :
Decrease skin inflammation
Reduce immune overactivity
Support restoration of normal skin color in vitiligo
RUTINIB CREAM Ruxolitinib 1.5% Application & Administration
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RUTINIB CREAM Ruxolitinib 1.5%
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