Trazine-S Tablet combining Trifluoperazine (an antipsychotic) and Trihexyphenidyl (an anticholinergic) used to treat schizophrenia, acute anxiety, and psychotic disorders. It manages delusions, hallucinations, and paranoia while preventing movement-related side effects (tremors, muscle stiffness) caused by antipsychotics.
Key Uses and Benefits :
Schizophrenia: Manages symptoms like hallucinations, delusions, and disorganized thinking.
Anxiety and Tension: Reduces restlessness and severe anxiety.
Movement Disorder Prevention: Trihexyphenidyl prevents extrapyramidal symptoms (shaking, spasms) often caused by antipsychotic medications.
Psychotic Illness: Helps improve mood and behavior
How It Works :
Trifluoperazine balances dopamine activity in the brain to control psychotic symptoms.
Trihexyphenidyl reduces movement-related side effects caused by dopamine blockade.
Main Uses :
Schizophrenia
Reduces hallucinations, delusions, disturbed thinking, and agitation.
Other Psychotic Disorders
Helps control severe behavioral disturbances and psychotic symptoms.
Severe Anxiety (in selected cases)
Sometimes prescribed short-term when anxiety is intense and not responding to other medicines.
Prevention of Movement Side Effects
The trihexyphenidyl component helps prevent or reduce:
Muscle stiffness
Tremors
Restlessness
Drug-induced Parkinsonism
(These can occur due to antipsychotic treatment.)
Indications :
Used in:
Schizophrenia
Other psychotic disorders
Severe anxiety (in selected cases)
Prevention of extrapyramidal side effects (movement stiffness, tremors) caused by antipsychotics
Pharmacological Class :
Trifluoperazine: Typical (first-generation) antipsychotic – phenothiazine class
Trihexyphenidyl: Antiparkinsonian agent (reduces drug-induced movement
Composition (Typical) :
Each tablet usually contains:
Trifluoperazine Hydrochloride – 5 mg (antipsychotic)
Trihexyphenidyl Hydrochloride – 2 mg (anticholinergic)
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