Nindanib 150 mg Capsule is a tyrosine kinase inhibitor primarily used to treat idiopathic pulmonary fibrosis (IPF) and other chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype. It slows the decline of lung function by reducing scarring. It is also used in combination with docetaxel for certain non-small cell lung cancers.
Key Uses and Therapeutic Effects :
Idiopathic Pulmonary Fibrosis (IPF): Treats this progressive, irreversible lung disease, helping to reduce the rate of lung capacity decline by 50%.
Chronic Fibrosing Interstitial Lung Diseases (ILDs): Manages progressive lung diseases that cause scarring.
Systemic Sclerosis-Associated ILD (SSc-ILD): Used to slow the rate of decline in lung function in patients with this specific condition.
Non-Small Cell Lung Cancer (NSCLC): Used in combination with docetaxel to manage locally advanced, metastatic, or recurrent adenocarcinoma, typically after first-line chemotherapy has failed.
Nindanib contains nintedanib, an antifibrotic and anti-cancer medicine. It is mainly used to treat certain lung diseases and some cancers.
Key Properties :
Route of Administration: Oral (capsule to be swallowed whole)
Storage: Store below ~25–30 °C, in a cool, dry place, protected from moisture and light.
Typical Dosage: Often 150 mg twice daily with food
Therapeutic Class :
Class: Antifibrotic / Antineoplastic agent
Action: Tyrosine kinase inhibition — blocks receptors like VEGF, FGF, and PDGF involved in fibrosis and cell proliferation pathways.
Composition :
Active Ingredient:
• Nintedanib 150 mg (as the primary active compound) — a tyrosine kinase inhibitor that targets multiple signalling pathways involved in fibrosis and tumour growth.
Inactive Ingredients: Soft gelatin capsule shell and formulation excipients
Medicine Name: Nindanib 150 mg Soft Gelatin Capsule
Form: Oral soft gelatin capsule
Strength: 150 mg nintedanib per capsule (active ingredient)
Main Uses :
Idiopathic Pulmonary Fibrosis (IPF)
Slows the progression of lung scarring and helps preserve lung function.
Other Chronic Fibrosing Interstitial Lung Diseases (ILDs)
Used in progressive fibrosing lung conditions to reduce further lung damage.
Systemic Sclerosis-associated ILD (SSc-ILD)
Helps slow lung function decline in patients with scleroderma-related lung fibrosis.
Non-Small Cell Lung Cancer (NSCLC)
Used in combination with other medicines in certain types of advanced lung cancer.
How It Works :
Nintedanib blocks specific enzymes (tyrosine kinases such as VEGF, FGF, PDGF receptors) that are involved in:
Formation of scar tissue (fibrosis)
Growth of abnormal cells
Blood vessel formation in tumors
By blocking these pathways, it slows lung scarring and tumor growth.
CONTACT “Skyblue International“ For best price
CONTACT “Skyblue International“ For best price
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