Product Name: Ruxolitinib Cream (commonly marketed as Rutinib Cream 1.5%) Form: Topical cream for skin application Strength/Concentration: 1.5% w/w ruxolitinib (active ingredient) Composition : Active Ingredient: • Ruxolitinib 1.5% w/w — a Janus kinase (JAK1/JAK2) inhibitor that modulates inflammatory and immune signaling in the skin. Mechanism of Action : Ruxolitinib blocks JAK enzymes involved in immune signaling (JAK1 and JAK2). This reduces inflammation, modulates immune responses in the skin, and helps control inflammatory and pigmentary processes. Indications / Uses : This cream is used (on medical prescription) for the topical treatment of: Atopic dermatitis (eczema) — especially mild to moderate cases not adequately controlled by other topical therapies. Non-segmental vitiligo — to help promote repigmentation of depigmented skin patches in patients aged 12 years and older. Application & Administration : Apply a thin layer directly to affected skin areas as directed by your healthcare provider. Typically used twice daily on clean, dry skin, usually up to a limited body surface area. Avoid contact with eyes and mucous membranes. Rutinib cream contains ruxolitinib, a topical JAK (Janus kinase) inhibitor used to treat certain inflammatory and autoimmune skin conditions. Key Uses and Indications : Atopic Dermatitis (Eczema): Treats red, irritated, and itchy skin in patients with mild to moderate eczema. Vitiligo: Used for nonsegmental vitiligo in patients 12 and older, aiding in repigmentation of the skin. Mechanism of Action: As a Janus kinase (JAK) inhibitor, it works by suppressing immune responses in the skin to reduce inflammation. Rutinib Cream 1.5% (containing Ruxolitinib) is a prescription topical JAK inhibitor used for the short-term treatment of mild-to-moderate eczema (atopic dermatitis) and nonsegmental vitiligo in adults and children 12 years and older. It reduces itching, inflammation, and helps restore skin pigmentation. How It Works : Ruxolitinib blocks JAK1 and JAK2 enzymes, which are involved in inflammatory and immune signaling pathways. This helps : Decrease skin inflammation Reduce immune overactivity Support restoration of normal skin color in vitiligo

Medicine Name: REDNISOL‑16 Tablet Active Ingredient: Methylprednisolone — 16 mg per tablet Drug Class: Corticosteroid (Glucocorticoid) Formulation: Uncoated oral tablets Manufacturer: Leeford Healthcare Ltd (India) Pack Size: Typically strip of 10 tablets Mechanism of Action : Rednisol works by suppressing the immune system and reducing inflammation. It blocks chemical messengers that cause redness, swelling, and allergic reactions in the body. Common Uses : REDNISOL 16 mg is typically prescribed for conditions involving inflammation and overactive immune responses, including: Allergic reactions and severe allergies Asthma and respiratory inflammatory conditions Rheumatic and joint disorders (e.g., rheumatoid arthritis) Autoimmune diseases such as systemic lupus erythematosus Skin disorders (e.g., eczema, psoriasis) Eye inflammatory conditions Some endocrine, intestinal, blood, or collagen disorders REDNISOL 16 mg (Methylprednisolone) is a corticosteroid, mainly used to reduce inflammation and suppress overactive immune responses. Allergic Conditions: Treatment of severe allergies, drug-induced hypersensitivity, and allergic rhinitis. Inflammatory Disorders: Manages conditions like arthritis, lupus, and psoriatic arthritis by reducing inflammation, pain, and swelling. Respiratory Issues: Used to treat asthma and other breathing problems. Skin & Eye Conditions: Treats skin disorders like eczema and psoriasis, as well as eye diseases like optic neuritis and uveitis. Autoimmune Conditions: Helps in managing immune system disorders like ulcerative colitis and Crohn's disease. Organ Transplant: Used to prevent rejection of transplanted organs. Rednisol 16 MG tablet contains Methylprednisolone, a corticosteroid used to treat severe allergies, asthma, rheumatic disorders, skin diseases (eczema, psoriasis), lupus, eye conditions, and certain cancers. It works by reducing inflammation and suppressing the immune system. It is also used to prevent organ rejection.

Active Ingredient: Dexamethasone Sodium Phosphate equivalent to 4 mg dexamethasone per ml of solution — a potent glucocorticoid (steroid). Dosage Form: Sterile solution for injection (parenteral). Strength: 4 mg dexamethasone per ml, typically supplied in a 2 ml ampoule/vial (total 8 mg per vial). Therapeutic Class: Systemic corticosteroid (anti-inflammatory / immunosuppressant). Mechanism of Action: Dexamethasone works by binding glucocorticoid receptors and reducing the production and release of inflammatory substances, suppressing immune responses and preventing inflammation. Route of Administration: Given intravenously (IV) or intramuscularly (IM) by a healthcare professional (not for self-administration). Packaging & Storage: Usually 2 ml ampoules in strips or boxes. Store at room temperature, protected from light and moisture Dexona 4 mg Injection (Dexamethasone) is a potent corticosteroid used to treat severe inflammation, allergies, autoimmune diseases, and certain cancers. It manages conditions like rheumatoid arthritis, asthma, skin rashes (eczema), and cerebral edema. It acts by suppressing the immune system and reducing inflammatory chemicals. Inflammatory Conditions: Treats arthritis, ankylosing spondylitis, and skin/collagen disorders. Severe Allergies: Manages acute allergic reactions, bronchial asthma, and drug-induced hypersensitivity. Autoimmune Disorders: Used in conditions like systemic lupus erythematosus (SLE). Brain and Eye Issues: Reduces brain swelling (cerebral edema) and treats eye inflammation like iritis or uveitis. Cancer Therapy: Used in leukemia and lymphoma to manage specific symptoms and improve quality of life. Other Uses: Treats adrenal insufficiency, blood disorders (low platelets), and prevents post-operative shock. DEXONA Injection is a corticosteroid used to treat conditions involving severe inflammation, allergy, or immune response. Main Uses : Severe allergic reactions (anaphylaxis, angioedema) Acute inflammatory conditions Asthma and severe respiratory conditions Cerebral edema (brain swelling) Severe infections (as supportive therapy to reduce inflammation) Autoimmune diseases Shock and emergency conditions Adjunct treatment in certain cancers Severe COVID-19 cases (to reduce lung inflammation, as prescribed) How it Helps : Reduces inflammation and swelling Suppresses overactive immune response Helps stabilize patients in emergency situations

Generic Name: Methylprednisolone 4 mg Brand: MEPLIX 4 mg Tablet Dosage Form: Oral tablet Strength: 4 mg per tablet Therapeutic Class: Glucocorticoid corticosteroid (anti‑inflammatory and immunosuppressant) Active Ingredient Methylprednisolone – 4 mg A corticosteroid that reduces inflammation and suppresses immune system activity. How It Works MEPLIX 4 mg works by blocking the release of chemicals in the body that cause inflammation (redness, swelling) and allergic reactions. It also suppresses the immune system, making it useful in conditions caused by immune system overactivity. Meplix 4mg Tablet is a corticosteroid used to treat inflammatory, allergic, and autoimmune conditions like arthritis, lupus, asthma, and severe allergies by suppressing the immune system. It reduces swelling, pain, and itching by inhibiting inflammatory substances. Common uses include treating skin diseases, eye disorders, and ulcerative colitis. Allergic Conditions: Treatment of severe allergies, including allergic reactions. Inflammatory Diseases: Manages conditions like arthritis, lupus (systemic lupus erythematosus), and ulcerative colitis. Respiratory Issues: Used for asthma and other breathing problems. Skin and Eye Disorders: Treats various, often severe, skin (e.g., psoriasis) and eye conditions. Immune System Suppression: Reduces immune response in autoimmune disorders. MEPLIX 4 mg Tablet is used to treat a wide range of inflammatory and immune‑related conditions, including: Allergic conditions (e.g., severe allergic reactions, asthma flare‑ups) Rheumatic and autoimmune disorders (e.g., rheumatoid arthritis, lupus) Skin disorders (e.g., eczema, psoriasis) Eye inflammations (e.g., allergic eye reactions) Systemic lupus erythematosus (SLE) Other conditions where inflammation and immune response need to be controlled Allergic Conditions Severe allergies, hay fever, asthma flare-ups, and other allergic reactions. Inflammatory Disorders Rheumatoid arthritis, osteoarthritis flare-ups, lupus, and other autoimmune diseases. Reduces joint pain, swelling, and stiffness. Skin Disorders Eczema, psoriasis, dermatitis, and other inflammatory skin conditions. Eye Inflammations Allergic conjunctivitis and other inflammatory eye conditions. Respiratory Conditions Asthma, COPD exacerbations, and other inflammatory lung conditions. Other Immune-Related Conditions Conditions where the immune system is overactive, such as systemic lupus erythematosus (SLE) or certain blood disorders.

Brand name: TACROHEAL Generic name: Tacrolimus Strength: 0.1% w/w Dosage form: Ointment Pack size: 10 g tube Drug class: Topical calcineurin inhibitor (immunomodulator) Steroid-free: Yes Composition Active ingredient: Tacrolimus 0.1% w/w Ointment base: q.s. (white soft paraffin / excipients – manufacturer specific) Indications Atopic dermatitis (eczema) Chronic inflammatory skin conditions Vitiligo (off-label, dermatologist Route of Administration Topical (external use only) Directions for Use Apply a thin layer to affected area Usually twice daily or as directed by physician TACROHEAL 0.1% Ointment (10 g) contains Tacrolimus 0.1%, an immunomodulator used on the skin. Uses of TACROHEAL 0.1% Ointment Atopic dermatitis (eczema) Used when other treatments (like topical steroids) are not suitable or not effective. Chronic eczema Helps reduce redness, itching, and inflammation. Sensitive skin areas Suitable for face, neck, skin folds where steroids are risky. Vitiligo (off-label use) Helps in repigmentation, especially on the face. Other inflammatory skin conditions As advised by a dermatologist. How It Works Suppresses local immune response in the skin Reduces inflammation, itching, and redness

Brand / Product: Diprobate RD Cream 30 gm Dosage Form: Topical cream (for external skin use only) Pack Size: 30 gm tube Manufacturer: Sun Pharmaceutical Industries Ltd Active Ingredient Betamethasone — 0.0125% w/w (a corticosteroid that reduces inflammation, redness, itching, and swelling of the skin) Pharmacological Class Corticosteroid (topical steroid) — works by suppressing inflammatory and allergic responses in the skin. Diprobate RD Cream is used to relieve symptoms of inflammatory or allergic skin conditions, including: Eczema Dermatitis Psoriasis Other itchy, inflamed skin conditions These conditions involve redness, swelling, itching, or irritation of the skin. This medicine contains betamethasone, a topical corticosteroid used on the skin to reduce inflammation, itching, redness, and swelling. It’s mainly used for: ✔ Eczema – Red itchy, dry, and inflamed patches of skin. ✔ Dermatitis – Skin irritation with itching and redness. ✔ Psoriasis – Scaly, itchy skin patches. ✔ Other allergic skin conditions where inflammation and itching occur

Brand Name : Etoshine 120 mg Tablet Active Ingredient : Etoricoxib 120 mg — a selective COX‑2 inhibitor Drug Class : Non‑Steroidal Anti‑Inflammatory Drug (NSAID) — specifically a selective COX‑2 inhibitor Formulation : Oral Tablet (film‑coated) Strength : 120 mg per tablet Mechanism of Action : Blocks COX‑2 enzyme, reducing production of prostaglandins that cause pain, inflammation, and swelling Etoshine 120 mg is a strong pain‑relieving and anti‑inflammatory medicine commonly Used for various musculoskeletal and inflammatory conditions. It’s part of the NSAID class but selectively targets the COX‑2 enzyme, which is primarily involved in inflammation and pain signals. ETOSHINE 120 mg contains Etoricoxib, a selective COX‑2 inhibitor NSAID (Non-Steroidal Anti-Inflammatory Drug). It is used for pain relief and reducing inflammation. Osteoarthritis (OA) Relieves joint pain and stiffness Improves mobility and daily function in OA patients Rheumatoid Arthritis (RA) Reduces joint inflammation, swelling, and pain Helps improve range of motion Ankylosing Spondylitis (AS) Helps manage spinal stiffness and pain caused by chronic inflammation Acute Pain & Gout Provides short-term relief from musculoskeletal pain Helps reduce pain and inflammation during gout attacks Benefits of Etoshine Tablet In Pain relief Etoshine 120 Tablet is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis or even after a dental (tooth-related) surgery.

Brand Name: Renocrit 4000 IU Injection Active Ingredient: Recombinant Human Erythropoietin Alfa (Epoetin alfa) – 4000 IU per dose Form: Injection (usually pre‑filled syringe of 0.4 ml) Drug Class: Erythropoiesis‑stimulating agent (ESA) Therapeutic Uses : Renocrit 4000 IU Injection is used to treat or manage anemia caused by: Chronic kidney disease (CKD) – including patients on dialysis or non‑dialysis. Anemia linked to cancer chemotherapy or cancer therapy. Anemia in patients treated with certain antiretroviral drugs (e.g., zidovudine for HIV). It may also be used to reduce the need for red blood cell transfusions before elective surgery in patients at high risk of blood loss. Administration : Route: Injected subcutaneously (under the skin) or intravenously (into a vein) under medical supervision. Dosage: Determined by a doctor based on body weight, hemoglobin levels, and response to treatment. (Active ingredient: Epoetin alfa 4000 IU per 0.4 ml) Main Uses : Anemia due to Chronic Kidney Disease (CKD) Helps increase red blood cell count in patients on dialysis or not on dialysis. Chemotherapy-Induced Anemia Used in cancer patients whose hemoglobin drops due to chemotherapy. HIV-Related Anemia For patients taking antiretroviral therapy (e.g., zidovudine) who develop low hemoglobin. Reduction of Blood Transfusions Pre-surgery or in conditions with expected high blood loss, to reduce the need for red blood cell transfusions. RENOCRIT 4000 IU Injection is a prescription medicine containing Epoetin alfa, used to treat anemia (low red blood cell count) caused by chronic kidney disease (both on and off dialysis), cancer chemotherapy, and HIV treatment (zidovudine). It stimulates bone marrow to produce more RBCs, reducing the need for blood transfusions. Key Uses and Indications : Chronic Kidney Disease (CKD) Anemia: Treats, prevents, or manages anemia in adult and pediatric patients with kidney failure. Cancer Chemotherapy-Induced Anemia: Helps raise hemoglobin levels in patients with non-myeloid malignancies. HIV-Associated Anemia: Manages anemia resulting from zidovudine therapy. Surgery Support: Reduces potential red blood cell transfusions in patients undergoing elective, non-cardiac, non-vascular surgery. How It Works : Renocrit contains a synthetic form of erythropoietin, a hormone that stimulates the bone marrow to produce red blood cells, helping improve oxygen transport and reduce symptoms of anemia. Stimulates the bone marrow to produce more red blood cells. Improves oxygen delivery to tissues and reduces symptoms like fatigue, weakness, and shortness of breath.

Brand Name: Answell Tablet Active Ingredients: Ibuprofen 400 mg – non‑steroidal anti‑inflammatory drug (NSAID) Paracetamol 325 mg (also called acetaminophen) – analgesic/antipyretic Dosage Form: Oral tablet Strength: 400 mg ibuprofen + 325 mg paracetamol per tablet How It Works : Ibuprofen: Reduces pain, inflammation, and swelling by blocking substances (prostaglandins) that cause these symptoms. Paracetamol: Helps reduce pain and fever by acting on the brain’s temperature and pain‑control centers. Together, they relieve mild to moderate pain, inflammation, and fever more effectively than either alone. (Contains Ibuprofen 400 mg + Paracetamol 325 mg) Main Uses : Pain Relief (Analgesic) Headache, toothache, muscle pain, joint pain, backache Menstrual pain (dysmenorrhea) Fever Reduction (Antipyretic) Helps lower high temperature due to infection or inflammation Inflammation Reduction Swelling and discomfort caused by arthritis, minor injuries, or musculoskeletal pain Post-Operative or Post-Traumatic Pain Relief from mild to moderate pain after minor surgery or trauma Answell Tablet is a combination medication containing Ibuprofen (400 mg) and Paracetamol (325 mg), primarily used to relieve mild to moderate pain, reduce fever, and manage inflammation. It is commonly used for headaches, muscle aches, menstrual cramps, toothaches, and joint pain associated with arthritis. Key Uses of Answell Tablet : Pain Relief: Effectively treats short-term pain, including sprains, strains, dental pain, and postoperative discomfort. Inflammation Reduction: Used for swelling and inflammation in joints (rheumatoid arthritis, osteoarthritis) and other conditions. Fever Reduction: Lowers high temperature and reduces fever. Headaches and Migraines: Provides relief from severe headaches and migraine pain. How It Works : Ibuprofen: Blocks prostaglandins, reducing pain, inflammation, and swelling Paracetamol: Reduces pain and fever by acting on the brain’s temperature and pain centers