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'modulating calcium channels'

Items tagged with 'modulating calcium channels'

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Chronic Pain Treatment

PREGABALIN CAPSULES 75mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Nervigesic 75mg Capsule belongs to the anti-epileptic group of medicines and can also be used to treat certain types of seizures (fits) in combination with other medicines. Additionally, it may also be prescribed to treat the symptoms of anxiety disorder if other medicines are not suitable. 1. Neuropathic Pain Treats nerve pain caused by: Diabetes (Diabetic Neuropathy) Spinal cord injury Post-herpetic neuralgia (after shingles) Sciatica Peripheral neuropathy Mechanism: Calms overactive nerves by modulating calcium channels in the nervous system. 2. Fibromyalgia Reduces widespread musculoskeletal pain, fatigue, and sleep problems common in fibromyalgia patients. 3. Epilepsy (Partial-Onset Seizures) Used as adjunct therapy with other anti-epileptic drugs to control focal seizures. 4. Generalized Anxiety Disorder (GAD) (Off-label in some countries) Helps reduce anxiety by acting on brain signaling, similar to benzodiazepines but without the same dependency profile.

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Pharmaceutical Tablets

PREGALYV 75 MG, PREGABALIN Capsules Pregaliv 75 Tablet SR is a prescription medicine used for the treatment of neuropathic pain. It decreases pain by modulating calcium channel activity of the nerve cells. This medicine also protects nerve fibers and heal damaged nerve cells. Pregaliv 75 Tablet SR is taken by mouth with or without food, preferably at bedtime. It is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as this is a habit-forming medicine. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor. Some common side effects of this medicine include nasopharyngitis, increased appetite, euphoric mood, tremor, blurred vision, dry mouth, dizziness, and sleepiness. Do not drive or do anything that requires mental focus until you know how this medicine affects you. The side effects are mild in nature and get improve with time. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. ⚙️ How It Works Pregabalin, the active ingredient, binds to calcium channels in the central nervous system, inhibiting excitatory neurotransmitter release. This action helps in reducing abnormal electrical activity in the brain and alleviates pain by calming overactive nerves. ⚠️ Side Effects Common Side Effects: Dizziness Drowsiness Dry mouth Weight gain Swelling of hands or feet Blurred vision Difficulty concentratingWellness Forever+1Wellness Forever+1 Serious Side Effects: Severe allergic reactions (e.g., trouble breathing, swelling of the face or throat) Mood or mental changes (e.g., depression, suicidal thoughts) Unusual fatigue or weakness Vision problems If you experience any of these serious side effects, seek medical attention promptly. ⚠️ Warnings & Precautions Allergic Reactions: Do not take Pregalyv 75 mg if you are allergic to pregabalin or any other ingredients. Pregnancy & Breastfeeding: Consult your doctor before use during pregnancy or breastfeeding. Kidney Function: Use with caution in patients with kidney problems; dosage adjustments may be necessary. CNS Effects: May cause dizziness, drowsiness, and blurred vision. Avoid activities requiring full alertness until you know how the medication affects you. Alcohol Interaction: Avoid alcohol as it can increase the risk of side effects like drowsiness and dizziness.

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Sexual & Reproductive Health Peptides

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Generic Name :- Kisspeptin-10 Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins 1. Stimulation of Gonadotropin-Releasing Hormone (GnRH) Kisspeptin-10 stimulates the hypothalamus to release GnRH, which then promotes the secretion of: Luteinizing hormone (LH) Follicle-stimulating hormone (FSH) This cascade is crucial for puberty onset, ovulation, and fertility regulation. 2. Fertility Research Used in assisted reproductive technologies (ART) and IVF studies to promote natural hormonal responses. Can potentially reduce the need for synthetic hormones like hCG. 3. Hypogonadism and Delayed Puberty Investigated as a treatment for hypogonadotropic hypogonadism (low LH/FSH due to low GnRH). May help restore reproductive function in affected individuals. 4. Polycystic Ovary Syndrome (PCOS) Studied for its role in correcting LH/FSH imbalances in PCOS patients. 5. Diagnostic Use Used to test pituitary function or the integrity of the hypothalamic-pituitary-gonadal (HPG) axis. BUY Kisspeptin-10 5mg IN CHEAP PRICE GET BEST OFFERS ON Kisspeptin-10 5mg FROM US SKYBLUE INTERNATIONAL

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Neurological & Cognitive Peptides

Semax 30mg Peptide uses & doses USA fast delivery Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ 🧠 Primary Uses of Semax (30mg): 1. Cognitive Enhancement (Nootropic Use) Improves memory, focus, mental clarity, and learning ability Enhances executive function and creativity Often used by students, professionals, and biohackers 2. Neuroprotection Protects neurons from oxidative stress and damage Used in Russia after strokes, traumatic brain injuries, or brain surgeries 3. Mood and Stress Regulation Reduces symptoms of depression, anxiety, and mental fatigue Regulates stress by modulating the adrenal response and dopamine system 4. Treatment for ADHD & Cognitive Disorders Can support focus and impulse control in individuals with ADHD Sometimes used off-label to enhance dopaminergic transmission 5. Improved Recovery After Neurological Events Clinically used in post-stroke therapy in Russia Enhances cerebral blood flow and helps with neurological rehabilitation 6. Immune System Modulation May boost immune system response and inflammatory regulation Form Typical Dose Route Frequency 30mg vial (powder) 200–600 mcg per dose Intranasal (most common) 1–3 times per day

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