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Diabetes & chronic weight management

TIZARO TIRZEPATIDE 10mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Brand Name: TIZARO' prominently printed. Strength: 10 mg clearly stated. Composition: Tirzepatide listed. Manufacturer :- ZISKA PHARMA Description Tizaro is a once weekly antihyperglycemic medication. Tizaro contains an active substance called Tirzepatide is used to treat adults with type 2 diabetes mellitus. Tizaro 10 mg is a higher-dose injectable form of tirzepatide, a dual GIP + GLP-1 receptor agonist Type 2 Diabetes Mellitus Chronic Weight Management (Obesity) Approved use to improve blood sugar control Reduces both fasting and post-meal glucose levels Lowers HbA1c by up to 2.4% in clinical trials Used in combination with: Metformin SGLT2 inhibitors Basal insulin (if required) Approved for adults with: BMI ≥30 (obese), or BMI ≥27 (overweight) with other conditions (diabetes, hypertension, etc.) Stronger appetite suppression More rapid fat burning and weight reduction Average weight loss of 15–22% over several months (as seen in SURMOUNT trials) BUY IT NOW IN USA BUY IT NOW IN UNITED KINGDOM BUY IT NOW IN AUSTRALIA BUY IT NOW IN EUROPE

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Diabetes & chronic weight management

TIZARO TIRZEPATIDE 2.5mg BUY IN USA, CANADA, SINGAPORE, AUSTRALIA Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Type 2 Diabetes Management TIZARO 2.5mg is used alongside diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It enhances insulin secretion and reduces glucagon levels in a glucose-dependent manner. Additionally, it improves insulin sensitivity, aiding in more effective glucose utilization . Weight Management While not officially approved for weight loss, tirzepatide has shown potential in reducing body weight. It may suppress appetite, slow gastric emptying, and increase satiety, which can be beneficial for overweight individuals, particularly those with metabolic disorders Enhancing glucose-dependent insulin secretion Suppressing glucagon Improving insulin sensitivity Delaying gastric emptying to control blood sugar levels Chronic Weight Management Approved for obesity and overweight individuals with comorbidities, due to its: Appetite suppression and increased satiety Slower gastric emptying Significant fat and weight loss demonstrated in clinical trials Cardiovascular & Metabolic Benefits Lowers blood pressure and improves lipid profile Reduces inflammatory markers linked to metabolic syndrome Dosage Details (2.5 mg) Starting dose: 2.5 mg subcutaneous injection once weekly for approximately 4 weeks to minimize GI side effects Administration sites: Abdomen, thigh, or upper arm; consistent day each week BUY NOW FROM US WITH BEST DEALS & OFFERS

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Growth Hormone Secretagogues

CJC-1295 DAC (5mg) FAST DELIVERY TO AUSTRALIA SKYBLUE INTERNATIONAL is a trusted global pharmaceutical export company specializing in the export of high-quality medicines. With a strong commitment to healthcare excellence, we supply a wide range of branded and generic medicines to countries including the USA, UK, Australia, UAE, Canada, Singapore, and the Philippines. Our focus is on reliability, compliance, and timely delivery to meet the global demand for affordable and effective medical solutions. Medicine 💊 USES : CJC-1295 DAC (Drug Affinity Complex) is a long-acting growth hormone-releasing hormone (GHRH) analog designed to elevate IGF-1 and growth hormone (GH) levels for days after a single injection. Below is a detailed breakdown of its primary applications, mechanisms, and protocols. Fat Loss & Metabolism Boosts lipolysis (fat breakdown), especially stubborn visceral fat. Improves insulin sensitivity → Supports metabolic health. Mechanism: Binds to GHRH receptors in the pituitary → sustained GH release (elevates IGF-1 for 5-7 days per dose). Half-life: 6-8 days (due to DAC modification, which prevents rapid breakdown). Key Difference vs. CJC-1295 (no DAC): CJC-1295 DAC → Long-lasting effects (fewer injections needed). Standard CJC-1295 → Shorter duration (requires daily dosing). Standard Protocol (5mg Vial) Reconstitution: Mix with 2mL bacteriostatic water (yields 2.5mg/mL). Dosing: Beginner: 1mg (0.4mL) 2x/week (e.g., Monday & Thursday). Advanced: 2mg (0.8mL) 2x/week (for maximum IGF-1 elevation). Cycle Length: 8-12 weeks (followed by a 4-week break). ✅ Best for: Athletes wanting sustained muscle growth & recovery. Men/women targeting fat loss + anti-aging benefits. Those who prefer fewer injections (vs. daily peptides). WE EXPORT IN UK WE EXPORT IN SINGAPORE WE EXPORT IN DUBAI WE EXPORT IN JAPAN WE EXPORT IN CANADA

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Growth Hormone Secretagogues

The first 29 amino acids of GHRH were discovered to be as equally potent as its full 44 amino acid structure[1][2] This fragment became known as GRF (1-29). However, due to a rapid metabolic clearance analogues of GRF (1-29) were synthesized to enhance the biological activity and reduce the rapidity of metabolic clearance. These analogues were primarily created by substituting amino acids within the peptide structure for amino acids more resistant to enzymatic cleavage. One early analogue substituted the amino acid L-alanine (abbreviated as Ala or A) at the 2nd position of the peptide structure for its optical isomer (mirror image), D-alanine (abbreviated as D-Ala). This substitution resulted in a peptide bond between D-Ala and the 3rd amino acid in the structure aspartic acid (Asp) more able to resist rapid cleavage by the enzyme dipeptidyl peptidase-4, a cleavage which had previously led to an inactive peptide fragment.[3][4] This successful modification prompted the further creation of analogues with additional amino acid substitutions. Ipamorelin: A selective growth hormone secretagogue, Ipamorelin stimulates the release of GH by mimicking ghrelin's action on the ghrelin receptor. It is known for its specificity and minimal side effects compared to other GH-releasing peptides. Mod GRF 1-29 (CJC-1295 without DAC): This is a modified version of the first 29 amino acids of growth hormone-releasing hormone (GHRH). The modifications extend its half-life and enhance its ability to stimulate the pituitary gland to release GH. It is often used in research to study GH secretion patterns and related metabolic effects. ⚖️ Dosage and Composition The 5/5 mg blend indicates that each vial contains 5 mg of Mod GRF 1-29 and 5 mg of Ipamorelin, totaling 10 mg per vial. This combination is designed to provide a balanced stimulation of GH release, potentially offering synergistic effects when used in research protocols. 🔬 Research Applications In scientific studies, this peptide blend is utilized to: Study Growth Hormone Dynamics: Investigating the patterns and regulation of GH secretion. Metabolic Research: Understanding the role of GH in metabolism, including fat metabolism and muscle growth. Aging and Longevity Studies: Exploring the effects of GH on aging processes and potential therapeutic applications. Sleep and Recovery Research: Examining how GH influences sleep patterns and recovery processes. ⚠️ Important Considerations Research Use Only: These peptides are intended strictly for laboratory research and are not approved for human or veterinary use. Legal Status: The legality of purchasing and possessing these peptides varies by country and jurisdiction. It's essential to consult local regulations before acquiring them. Storage and Handling: Proper storage conditions are crucial to maintain peptide stability. Typically, lyophilized peptides should be stored at -20°C or colder and protected from light. Reconstitution should be done with appropriate solvents, and solutions should be stored at 4°C and used within a specified timeframe. Mod GRF 1-29 + Ipamorelin (5/5 mg) is primarily used in scientific research and clinical studies to investigate its effects on human growth hormone (GH) release and related metabolic functions. It is not FDA-approved for general medical use, but here are the commonly researched uses and potential applications: Stimulation of Growth Hormone (GH) Release Both peptides work synergistically to enhance the natural pulsatile release of GH from the pituitary gland. Mod GRF 1-29 initiates GH release, while Ipamorelin amplifies it by mimicking ghrelin. Anti-Aging Studies GH has regenerative effects on tissues, so researchers study this combo to explore its potential for: Improving skin elasticity Increasing energy levels Enhancing sleep quality Muscle Growth and Recovery (in studies) GH can help stimulate muscle protein synthesis and recovery. This combo is sometimes researched for its effects on lean muscle mass and exercise recovery. Fat Loss & Metabolic Support GH mobilizes stored fat, making this blend of interest in obesity and metabolic syndrome research. May support lipolysis (fat breakdown) in clinical models. Bone Density Studies GH supports bone mineralization. This combo is explored for potential applications in osteopenia/osteoporosis research. Sleep Improvement GH release is tied to deep sleep stages; researchers observe whether this combo improves sleep architecture and REM sleep. Modified GRF (1-29) acts to increase growth hormone production and release by binding to the growth-hormone-releasing hormone receptor (GHRHR) on cells in the anterior pituitary.

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Growth Hormone Secretagogues

Ipamorelin works by binding to IGF-1 receptors in the body and mimicking its effects on those receptors. This causes an increase in muscle mass and strength, as well as fat loss due to increased metabolism and lipolysis (the breakdown of fat). Semorelin + Ipamorelin (5mg/5mg) – Key Uses, Benefits & Protocol This growth hormone (GH)-stimulating peptide blend is used for anti-aging, fat loss, muscle growth, and recovery. 1. Primary Uses A. Anti-Aging & Longevity Boosts collagen → Improves skin elasticity, reduces wrinkles. Enhances sleep quality → Deepens REM sleep for cellular repair. Supports cognitive function → May improve memory/focus. B. Fat Loss & Metabolism Reduces stubborn fat (especially visceral/belly fat). Improves insulin sensitivity → Helps with metabolic disorders. C. Muscle Growth & Recovery Increases lean muscle mass (without water retention). Speeds up injury recovery (tendons, ligaments, joints). D. Performance Enhancement (Athletes/Bodybuilders) Enhances workout recovery → Less soreness, faster gains. Preserves muscle during cutting phases. 2. How It Works Sermorelin → Stimulates natural GH release from the pituitary. Ipamorelin → A selective GH secretagogue (avoids cortisol/prolactin spikes). Synergy: More sustained GH pulses than either peptide alone. (Unlike synthetic HGH, this combo promotes natural, balanced GH secretion.) 3. Dosage & Administration Standard Dose: 5mg Sermorelin + 5mg Ipamorelin per vial (mixed with bacteriostatic water). Daily Injection: 100-300mcg each (e.g., 100mcg Sermorelin + 100mcg Ipamorelin). Typically 1-2 injections/day (morning and/or before bed). Cycle Length: 8-12 weeks (then take a 4-week break). 4. Expected Results & Timeline 📌 4-6 Weeks: Better sleep, increased energy, reduced body fat. 📌 8-12 Weeks: Visible muscle tone, tighter skin, faster recovery. 📌 3+ Months: Long-term anti-aging benefits (if cycled properly). (Best paired with strength training + high-protein diet.) 7. Alternatives to Consider Peptide Best For Pros Cons Tesamorelin + Ipamorelin Fat loss (visceral) FDA-approved (for HIV lipodystrophy) Expensive Final Verdict ✅ Best for: Anti-aging (skin, cognition, longevity). Athletes seeking muscle growth + recovery. Men/women targeting stubborn fat. . Detailed Benefits & Science How it compares to HGH or other peptides (like CJC-1295). Anti-aging mechanisms (collagen, cellular repair). 2. Cycle Recommendations Optimal dosing (e.g., 100mcg vs. 300mcg per day). How long to run it (8 vs. 12 weeks). 5. Success Stories/User Experiences Real-world results for fat loss, muscle gain, or skin improvement. Increased energy levels: sermorelin and ipamorelin help boost energy and stamina, allowing you to feel more active and engaged throughout the day. Improved sleep quality: By enhancing restorative sleep, sermorelin and ipamorelin can lead to better overall health and well-being. Sermorelin is a peptide hormone that is structurally similar to growth hormone-releasing hormone (GHRH). It is typically used to treat growth hormone deficiency in children and adults. It can also be used for other conditions, such as improving wound healing, reducing fat mass, and increasing muscle mass. Sermorelin and Ipamorelin peptides are often combined because they have synergistic properties. Research has proven them to help slow down the aging process, increase muscle mass, decrease fat mass, reduce inflammation, heal the gut and more. How often should I take Sermorelin? A dosage of 0.2-0.3 mcg once daily at bedtime by subcutaneous injection is recommended. Ipamorelin is a peptide that has been shown to increase growth hormone levels in humans by stimulating the hypothalamus, which is responsible for regulating the secretion of growth hormone. Ipamorelin works by binding to IGF-1 receptors in the body and mimicking its effects on those receptors. This causes an increase in muscle mass and strength, as well as fat loss due to increased metabolism and lipolysis (the breakdown of fat). When Can I Expect To See Results? While patients will notice some significant increases changes in the body after the first month, the full-benefits are usually fully noticed after three to six months of therapy. Month 1 * Increased energy * Improved stamina * Deeper, more restful sleep Month 2 * Improved skin, reduced wrinkles * Stronger nails and hair * Increased metabolism Month 3 * Enhanced sex drive and performance * Improved mental focus * Improved joint health Month 4 * Continued weight reduction * Improved skin elasticity * Increased lean muscle mass Month 5 * Noticeably fuller and healthier hair * Reduced appearance of wrinkles, better skin tone * Continued reduction in belly fat Month 6 * 5-10% reduction in body fat (without exercise/diet) * 10% increase in lean muscle mass * Improved vitality due to organ regrowth WE EXPORT TO USA WE EXPORT TO UK WE EXORT TO CANADA WE EXPORT TO SINGAPORE WE EXPORT

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Erectile Dysfunction Medicines

TADALAFIL, CHEWABLE VIDALISTA - CT 20mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, UK, EUROPE, UAE & GET 20% OFF ON BULK ORDER Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ Erectile Dysfunction (ED) Designed to treat ED by inhibiting PDE‑5, which boosts cGMP levels, relaxing penile blood vessels, and improving erection firmness upon arousal. Benign Prostatic Hyperplasia (BPH) Tadalafil may help relax prostate and bladder neck muscles, easing urinary symptoms in BPH. Pulmonary Arterial Hypertension (PAH) Though primarily for ED, tadalafil is also used in PAH. Vidalista CT 20 mg may likewise be used under a physician’s direction. Chewable tablet: Chew thoroughly before swallowing, for faster absorption—typically works within 15–30 minutes, or up to 30–60 minutes Timing: Take about 30–60 min before sex; effects may last up to 36 hours Frequency: Only once every 24 hours. Food and drink: Can be taken with/without food. Avoid high-fat meals, alcohol, grapefruit juice for best effect. Special note: Some sources erroneously say “place under tongue,” but chew is standard; tablets shouldn’t be swallowed whole. Vidalista Ct 20 mg is a class PDE5 inhibitor medication which is used to treat erectile dysfunction (ED) or impotence in men. Most men have the complaint of dissatisfied sexual intercourse due to a softer erection which even leads to breakups. BUY IT NOW & GET BEST DEALS

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Erectile Dysfunction Medicines

CENFORCE PRO SILDENAFIL CITRATE SUBLINGUAL TABLETS 100mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, UK, EUROPE, UAE & GET 20% OFF ON BULK ORDER Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ Cenforce Professional 100 mg is a fast-acting and effective sildenafil formulation designed for treating erectile dysfunction, with faster onset due to its chewable/sublingual delivery. It’s sometimes used off-label for pulmonary hypertension or blood pressure regulation, only on medical advice. It should be used once daily. USAGE :- Erectile Dysfunction (ED) in adult men Inhibits PDE‑5 → increases cGMP → relaxes smooth muscle → boosts blood flow to the penis during sexual arousal. Takes effect in about 30–60 minutes, lasting 4–6 hours, offering a reliable window for sexual activity. Sublingual/chewable tablet designed for faster absorption—dissolves under the tongue or is chewed and swallowed. Dosage :- Dose: One 100 mg tablet, no more than once every 24 hours Administration: Place under tongue or chew thoroughly, then swallow with water Can be taken with or without food, but avoid high-fat meals—they may delay onset Form Chewable/sublingual sildenafil 100 mg Onset 30–60 minutes Duration 4–6 hours Dose 1 tablet per 24 hours Use ED (primary), PAH or BP support (off‑label) Avoid with Nitrates, heavy meals, alcohol, grapefruit BUY IT NOW & GET BEST DEALS & DEALS

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Diabetes & chronic weight management

TIZARO TIRZEPATIDE 12.5mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Tirzepatide is FDA-approved to improve blood sugar (glucose) control in adults with type 2 diabetes, as an adjunct to diet and exercise. It is a once-weekly injectable medication. It works as a dual GIP and GLP-1 receptor agonist, enhancing insulin secretion, reducing glucagon levels, and slowing gastric emptying. It helps lower HbA1c and postprandial glucose levels. Although initially approved for type 2 diabetes, tirzepatide is also being used and studied for weight loss, especially under the brand name Zepbound (approved by the FDA in 2023 for chronic weight management). It is prescribed for people who are: Obese (BMI ≥30), or Overweight (BMI ≥27) with at least one weight-related condition (e.g., hypertension, type 2 diabetes, dyslipidemia). It reduces appetite and calorie intake significantly. 12.5 mg is typically a step-up dose. Patients usually start at a lower dose (e.g., 2.5 mg or 5 mg) and gradually increase every 4 weeks to minimize gastrointestinal side effects. 12.5 mg may be a maintenance or transitional dose toward the maximum dose of 15 mg/week, depending on individual tolerance and treatment goals. Generic Name Tirzepatide Brand Names Mounjaro (for diabetes), Zepbound (for weight loss) Dose Strength 12.5 mg Dosage Form Prefilled pen (subcutaneous injection) Route of Administration Subcutaneous (SC) – once weekly Appearance Clear, colorless to slightly yellow solution TIRZEPATIDE 12.5mg AVAILABLE IN INDIA AT BEST PRICE. https://www.skyblueinternationals.com/ LOOKING FOR GENERIC MEDICINES ??? https://www.skyblueinternationals.com/ TIRZEPATIDE 12.5mg AT LOWEST PRICE TIRZEPATIDE 12.5mg IN STOCK TIRZEPATIDE 12.5mg SHIPPING WORLD WIDE

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Diabetes & chronic weight management

TIZARO TIRZEPATIDE 7.5mg BUY'S IN CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ DISCRIBTION :- Type 2 Diabetes Mellitus (T2DM) Helps lower blood sugar (HbA1c) effectively Improves insulin sensitivity and secretion Reduces fasting and post-meal glucose spikes ➡️ Often used when 5 mg dose is tolerated well but greater glycemic control is needed. Weight Loss / Obesity Treatment Used for chronic weight management in: Adults with BMI ≥30, or BMI ≥27 with obesity-related conditions (diabetes, hypertension, etc.) At 7.5 mg, patients often report: Stronger appetite suppression Increased fat loss Accelerated body weight reduction vs lower doses ❤️ Cardiometabolic Benefits (Research-based) Helps reduce: LDL cholesterol and triglycerides Blood pressure Systemic inflammation (CRP) 7.5 mg Once weekly (SC injection) Injection sites Abdomen, thigh, upper arm Titration path 2.5 mg → 5 mg → 7.5 mg Max approved dose Up to 15 mg (in some proto How Tizaro Works (Mechanism) GLP-1 action: Enhances insulin release, slows gastric emptying, reduces appetite GIP action: Increases fat metabolism, improves insulin response Together, this dual pathway provides: Superior glucose control Greater weight loss vs other GLP-1 drugs (like semaglutide) BUY FROM US WORLD WIDE SHIPPING WITH GOOD PACKAGING CONTACT US FOR BEST OFFERS & DEALS

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