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Metabolic & Weight Management Peptides

Contact Us on telegram or WhatsApp +917887449821 +919168783773 +91 9529672584 +91 7499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://wa.me/c/917499402610 Name Semaglutide Purity ≥98% (as tested by HPLC, High-Performance Liquid Chromatography) CAS Number 910463-68-2 Molecular Formula C₁₈₇H₂₉₁N₄₅O₅₉ Molecular Weight ~4113.58 g/mol Peptide Sequence Modified GLP-1 (7-37) analog with substitutions to enhance stability Form Lyophilized powder (freeze-dried) Content 3mg per vial Semaglutide is a medication originally developed for type 2 diabetes and obesity treatment. It's a GLP-1 receptor agonist, meaning it mimics the hormone GLP-1, which helps regulate blood sugar and appetite. Type 2 Diabetes Management Lowers blood sugar by increasing insulin release and reducing glucagon secretion. Helps patients achieve better glycemic control. Weight Loss (Obesity or Overweight with Comorbidities) Reduces appetite and slows gastric emptying. FDA-approved under the brand name Wegovy for chronic weight management. 💉 Semaglutide 3mg – Dosing Guide (Research and Clinical Context) ✅ Clinically Approved Dosing (Prescription Use) Under brand names like Ozempic (for diabetes) and Wegovy (for weight loss), the FDA-approved semaglutide dosing follows this gradual titration to minimize side effects: Week Dose (Subcutaneous Injection) Weeks 1–4 0.25 mg once weekly Weeks 5–8 0.5 mg once weekly Weeks 9–12 1.0 mg once weekly (maintenance or increase as needed) Weeks 13+ 1.7 mg – 2.4 mg weekly (Wegovy max) or up to 2.0 mg (Ozempic max) Route: Subcutaneous injection (abdomen, thigh, or upper arm) Frequency: Once per week, same day/time ⚠️ Important Notes Side Effects: Can include nausea, vomiting, diarrhea, abdominal pain, and risk of pancreatitis. Not for Type 1 Diabetes or Ketoacidosis. Only certain brands and dosages are approved for specific uses.

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Erectile Dysfunction Medicines

TADALAFIL, VIDALISTA 80mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, UK, EUROPE, UAE & GET 20% OFF ON BULK ORDER Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ Mechanism of Action: Tadalafil, the active ingredient in Vidalista 80mg, belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. These medications work by relaxing the muscles in the penis and increasing blood flow, which facilitates an erection when a man is sexually aroused. Erectile Dysfunction (ED) As a high-dose PDE‑5 inhibitor, it blocks the enzyme that degrades cGMP, enhancing penile blood flow during sexual arousal. Effects typically begin within 30–60 minutes and can last up to 36 hours (or even up to 72 hours in some claims) Often chosen when lower doses haven’t been effective. However, many urologists caution this dose may be excessive and isn't well-studied . Benign Prostatic Hyperplasia (BPH) (less common/off-label) Tadalafil is FDA-approved for BPH, but in lower daily doses (5 mg). Some vendors claim 80 mg helps relax prostate/bladder neck muscles, though this isn't standard medical practice . Pulmonary Arterial Hypertension (PAH) (off-label/use caution) Tadalafil treats PAH in doses typically around 40 mg daily. Claims for PAH benefit at 80 mg are speculative and not backed by standard clinical guidelines.

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Chronic Pain Treatment

PREGABALIN CAPSULES 150mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ Nervigesic Capsules 450mg | Pregabalin IP 450mg (10 x 15 Capsules) | Neuropathic Pain Relief | Buy Online Product Description Powerful Neuropathic Pain Management with Nervigesic Capsules (Pregabalin IP 450mg) Experience targeted relief from nerve pain, fibromyalgia, and anxiety disorders with Nervigesic Capsules – formulated with high-strength Pregabalin IP 450mg. Each pack contains 150 capsules (10 strips x 15 capsules) for long-lasting therapy. Manufactured under strict pharmacopeial standards for guaranteed potency and safety. ✅ Key Benefits & Uses: Effective Dose: 450mg Pregabalin IP per capsule for severe neuropathic pain management. Trusted Relief: Treats diabetic neuropathy, spinal cord injury pain, post-herpetic neuralgia, and generalized anxiety disorder (GAD). Extended Supply: 150 capsules per pack – ideal for monthly treatment continuity. Fast-Acting: Reduces pain signals and calms overactive nerves within days. 🔬 Clinical Precision: Active Ingredient: Pregabalin IP 450mg (Aligned with Indian Pharmacopoeia standards). Dosage: Take exactly as prescribed (typically 1 capsule daily). Never self-medicate. Quality Assurance: Lab-tested for purity, dissolution, and stability.

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Diabetes & chronic weight management

TIZARO TIRZEPATIDE 2.5mg BUY IN USA, CANADA, SINGAPORE, AUSTRALIA Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Type 2 Diabetes Management TIZARO 2.5mg is used alongside diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It enhances insulin secretion and reduces glucagon levels in a glucose-dependent manner. Additionally, it improves insulin sensitivity, aiding in more effective glucose utilization . Weight Management While not officially approved for weight loss, tirzepatide has shown potential in reducing body weight. It may suppress appetite, slow gastric emptying, and increase satiety, which can be beneficial for overweight individuals, particularly those with metabolic disorders Enhancing glucose-dependent insulin secretion Suppressing glucagon Improving insulin sensitivity Delaying gastric emptying to control blood sugar levels Chronic Weight Management Approved for obesity and overweight individuals with comorbidities, due to its: Appetite suppression and increased satiety Slower gastric emptying Significant fat and weight loss demonstrated in clinical trials Cardiovascular & Metabolic Benefits Lowers blood pressure and improves lipid profile Reduces inflammatory markers linked to metabolic syndrome Dosage Details (2.5 mg) Starting dose: 2.5 mg subcutaneous injection once weekly for approximately 4 weeks to minimize GI side effects Administration sites: Abdomen, thigh, or upper arm; consistent day each week BUY NOW FROM US WITH BEST DEALS & OFFERS

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Miscellaneous Peptides

Prostamax 20mg, Peptide BUY IN USA, CANADA, SINGAPORE, AUSTRALIA Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪+919529672584‬ ‪ +917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Prostate Health & BPH support Designed to improve prostate function, reduce enlargement (BPH), and ease urinary symptoms (frequent urination, weak stream) It supports prostate cell regeneration, improves urine flow, and helps alleviate conditions like prostatitis Anti-inflammatory action in prostate tissue Exhibits localized anti-inflammatory effects in models of prostatitis and BPH Chromatin modulation & cellular reparative effects Alters DNA/chromatin structure — increasing chromatin accessibility, gene expression, and markers of DNA activity in prostate and lymphocyte cultures. Anti-aging / epigenetic influences Acts as an “anti-aging” peptide with epigenetic/regulatory effects, potentially applicable beyond prostate tissue. Mechanism of Action :- Sequence: Lys‑Glu‑Asp‑Pro (KEDP), molecular weight ~487 g/mol Chromatin remodeling: Promotes decondensation of heterochromatin, elevates sister chromatid exchange and rRNA gene activity — enabling DNA repair and expression Tissue regeneration: In vitro and animal models show reduced swelling, immune infiltration, and tissue scarring in prostate Dosage & Administration Common protocols: ~500–750 µg/day for 2–4 weeks via subcutaneous injection . Aspect Details Peptide Sequence Lys‑Glu‑Asp‑Pro (KEDP) Target Areas Prostate tissue, urinary system, lymphocytes Key Actions Anti-inflammatory, tissue repair, chromatin remodeling Dose Range ~500–750 µg/day via sub‑Q injection Typical Course 2–4 weeks, sometimes repeated after break Status Research only — not for clinical use BUY IN CANADA BUY IN SINGAPORE BUY IN AUSTRALIA BUY IN USA BUY IN ABU DHABI

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Sexual & Reproductive Health Peptide

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Generic Name Bremelanotide 1. Hypoactive Sexual Desire Disorder (HSDD) in Women FDA-approved in 2019 under the brand Vyleesi for pre-menopausal women with generalized HSDD unrelated to other medical or psychological condition Improves sexual desire, arousal, and reduces distress linked to low libido 2. Erectile Dysfunction (ED) in Men (Off‑Label) PT‑141 initiates erections via central nervous system pathways, increasing sexual desire and erection quality—even in men unresponsive to PDE‑5 inhibitors Demonstrated increased duration and rigidity of erections in trials 3. Sexual Arousal Support Boosts libido in both genders, addresses low sexual drive and arousal disorders, potentially enhancing orgasm quality and reducing refractory time Bremelanotide is a 7 amino acid peptide used to treat hypoactive sexual desire disorder in premenopausal women. Bremelanotide does not interact with alcohol. The mechanism by which bremelanotide's action on receptors translates to a clinical effect is still unknown. Bremelanotide was first described in the literature in 2003 when it was known by the investigational code PT-141.1 Since then it was investigated for its place in treating sexual dysfunction in men and women but is now only indicated for women.1,2,5 Other drugs used to treat female sexual dysfunction include flibanserin, estrogen, ospemifene, and prasterone. Bremelanotide was granted FDA approval Bremelanotide is an agonist of many melanocortin receptors which in order of potency are MC1R, MC4R, MC3R, MC5R, and MC2R.5 The mechanism by which agonism of these receptors translates to an improvement in hypoactive sexual desire disorder is currently unknown, however MC4R receptors are present in many areas of the central nervous system. MC3R and MC4R are found in the hypothalamus and are involved in food intake and energy homeostasis. Bremelanotide is a 7 amino acid and so its metabolism consists of multiple hydrolysis reactions.

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Healing & Regeneration Peptides

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+91 9529672584‬ ‪+91 7499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ BPC-157 (5mg) :- Abstract. BPC 157, a pentadecapeptide derived from human gastric juice, has been demonstrated to promote the healing of different tissues, including skin, muscle, bone, ligament and tendon. Full Name: Body Protective Compound-157 Source: Derived from a protein found in human gastric juice Molecular Weight: ~1,419 Da Form: Synthetic peptide, usually as a 5 mg lyophilized powder BPC-157 is FDA-approved but is widely studied in animal models and used off-label in sports medicine, biohacking, and functional medicine. 1. 🦴 Tendon, Ligament, and Muscle Healing Accelerates repair of torn tendons and ligaments (e.g. ACL, rotator cuff) Supports muscle regeneration after injury or surgery Enhances collagen synthesis and angiogenesis 2. 🧘‍♂️ Joint & Cartilage Repair Used in cases of arthritis, joint pain, and cartilage degeneration May protect chondrocytes and stimulate cartilage regeneration 3. 🧠 Neurological and Nerve Healing Promotes recovery of damaged peripheral nerves Shown to help in cases of traumatic brain injury (TBI) and nerve crush injuries (animal data) 4. 🧪 Gut Health Extremely effective in healing the GI tract Used for: IBD (Crohn’s, ulcerative colitis) Leaky gut syndrome Gastric ulcers NSAID-induced damage 5. 🔥 Anti-Inflammatory & Cytoprotective Reduces systemic inflammation and oxidative stress Protects cells from toxins, ischemia, and stress damage 6. 💉 Wound Healing & Skin Repair Speeds up recovery of burns, cuts, and abrasions May improve scarring and skin regeneration 7. 💪 Performance & Recovery Used by athletes to speed recovery from training or injury May help mitigate damage from overtraining BUY IT FROM US https://www.skyblueinternationals.com/

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NAD+ & Mitochondrial Support Peptides

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ NAD+ (Nicotinamide adenine dinucleotide), in a 100mg dose from Peptide Science, is used for a variety of potential benefits related to cellular health and function. These include supporting energy production, DNA repair, and combating the effects of aging. NAD+ plays a crucial role in numerous cellular processes, making it a subject of interest for both its potential therapeutic applications and its role in healthy aging. Energy Production: NAD+ is essential for the cellular energy production process, particularly in the mitochondria. It acts as a coenzyme, facilitating the transfer of electrons in redox reactions, which are crucial for ATP (energy) production. DNA Repair: NAD+ is a substrate for enzymes called PARPs, which play a vital role in repairing DNA damage. Maintaining sufficient NAD+ levels can help ensure proper DNA repair and genomic stability. ✅ Primary Uses of NAD⁺ (100mg) Cellular Energy Production NAD⁺ is essential for mitochondrial function, helping convert nutrients into ATP (energy). Often used to combat fatigue or low energy levels. Healthy Aging & Longevity NAD⁺ levels decline with age. Supplementation may support DNA repair, cellular health, and overall longevity via sirtuin activation (especially SIRT1). Cognitive Function May enhance brain health, memory, and focus by supporting neuronal function and reducing oxidative stress. Metabolic Support Helps regulate metabolism, insulin sensitivity, and weight management. May support healthy blood sugar levels. Addiction & Withdrawal Support (High-dose clinical setting) NAD⁺ IV therapy is sometimes used in detox programs to ease withdrawal symptoms and improve mental clarity. 100 mg is a low dose; IV protocols often use much higher amounts. Skin and Anti-Aging Products Included in some topical formulations to promote skin cell repair and reduce signs of aging. Sirtuin Activation: NAD+ is also required by sirtuins, a class of proteins involved in gene regulation, cellular stress responses, and potentially, longevity. Anti-Aging: Because NAD+ is involved in so many fundamental cellular processes, its decline with age is linked to various age-related changes. Maintaining NAD+ levels through supplementation is being explored as a way to potentially mitigate some of these changes and promote healthy aging.

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Metabolic & Weight Management Peptides

Tirzepatide (60mg) FAST DELIVERY TO FLORIDA Contact Us on telegram or WhatsApp +917887449821 +919168783773 +91 9529672584 +91 7499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Tirzepatide (60mg) Uses: Type 2 Diabetes: Tirzepatide is used to improve blood sugar control in adults with type 2 diabetes, often used with diet and exercise. Weight Management: It is also used for weight loss, particularly in adults who are overweight or obese, or who have weight-related medical problems. a synthetic peptide, a dual agonist for both GLP-1 (glucagon-like peptide 1) and GIP (glucose-dependent insulinotropic polypeptide) receptors. It is used to treat type 2 diabetes and may also be used for weight management. It works by mimicking the effects of two hormones involved in glucose regulation and appetite control, helping to lower blood sugar levels and potentially leading to weight loss. Tirzepatide is administered as a once-weekly subcutaneous injection. Dual Action: Tirzepatide targets both GLP-1 and GIP receptors, enhancing insulin sensitivity and potentially leading to weight loss. Mechanism of Action: It increases insulin secretion when blood sugar is high, lowers liver glucose production, and slows down food movement through the digestive tract, contributing to blood sugar control and weight loss. Administration: Tirzepatide is a subcutaneous injection, given once weekly. Potential Side Effects: Common side effects include nausea, vomiting, diarrhea, and constipation, especially during the initial dose escalation phase. Top Benefits of Tirzepatide :- Powerful Blood Sugar Control (Type 2 Diabetes) Lowers HbA1c levels significantly (up to 2.4% reduction) Helps regulate insulin and glucagon more effectively than GLP-1 drugs alone Outperforms other drugs like semaglutide and insulin degludec in trials

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