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'antiapoptotic properties'

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Sexual & Reproductive Health Peptides

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Generic Name :- Kisspeptin-10 Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins 1. Stimulation of Gonadotropin-Releasing Hormone (GnRH) Kisspeptin-10 stimulates the hypothalamus to release GnRH, which then promotes the secretion of: Luteinizing hormone (LH) Follicle-stimulating hormone (FSH) This cascade is crucial for puberty onset, ovulation, and fertility regulation. 2. Fertility Research Used in assisted reproductive technologies (ART) and IVF studies to promote natural hormonal responses. Can potentially reduce the need for synthetic hormones like hCG. 3. Hypogonadism and Delayed Puberty Investigated as a treatment for hypogonadotropic hypogonadism (low LH/FSH due to low GnRH). May help restore reproductive function in affected individuals. 4. Polycystic Ovary Syndrome (PCOS) Studied for its role in correcting LH/FSH imbalances in PCOS patients. 5. Diagnostic Use Used to test pituitary function or the integrity of the hypothalamic-pituitary-gonadal (HPG) axis. BUY Kisspeptin-10 5mg IN CHEAP PRICE GET BEST OFFERS ON Kisspeptin-10 5mg FROM US SKYBLUE INTERNATIONAL

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NAD+ & Mitochondrial Support Peptides

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+91 9529672584‬ ‪+91 7499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ SS-31 (25mg) :- SS-31, also known as elamipretide or Bendavia, is a mitochondria-targeting peptide that has shown potential in treating various conditions by improving mitochondrial function. It has been investigated for its antioxidant, anti-inflammatory, and anti-apoptotic properties, particularly in the context of neurodegenerative diseases, inflammatory diseases, and ischemia-reperfusion injury. SS-31 (also known as Elamipretide) is a synthetic peptide that targets and protects mitochondria, the energy-producing structures in cells. The 25 mg dose is commonly used in clinical trials and experimental protocols. Use Details 🫀 Heart Disease Improves heart function in heart failure and ischemic heart disease 🧠 Neurodegenerative Diseases May protect brain cells in conditions like Alzheimer’s, Parkinson’s 👁️ Eye Disorders Studied in dry age-related macular degeneration (dry AMD) 💪 Muscle Fatigue Helps with exercise intolerance and mitochondrial myopathy 🧬 Mitochondrial Dysfunction Repairs damaged mitochondria, boosts ATP production 🧫 Kidney Protection May reduce kidney injury in acute or chronic kidney disease 🧓 Age-Related Fatigue Improves mobility and stamina in older adults How It Works Targets mitochondria directly Binds to cardiolipin in the mitochondrial membrane Prevents oxidative damage Restores energy production (ATP) 💉 Common Dosage Form 25 mg usually administered subcutaneously (under the skin) once daily in studies. SS-31, also known as Elamipretide, is a synthetic peptide designed to improve mitochondrial function and reduce oxidative stress. It's primarily used to protect and restore mitochondrial function, specifically by reducing oxidative stress, stabilizing cardiolipin (a mitochondrial phospholipid), and improving mitochondrial energy production. Research suggests it may also be beneficial in conditions like Alzheimer's, brain injury, and kidney disease. The 25mg dosage refers to the amount of SS-31 in a single dose, often administered via injection. Mitochondrial Target: SS-31 specifically targets mitochondria, the powerhouses of cells, and is thought to protect and restore their function.

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Metabolic & Weight Management Peptides

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+91 9529672584‬ ‪+91 7499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ AOD9604 5mg retains the bone stimulating properties of human Growth Hormone. AOD9604 indicates that this drug may have a role in the prevention and possible treatment of osteoporosis, through direct action on osteoblasts, the cells which build new bone. AOD 9604 (5mg) is a synthetic peptide derived from the C-terminal fragment of human growth hormone (hGH). It has been studied for its potential benefits in fat metabolism and weight management. ✅ Uses of AOD 9604 Fat Loss and Weight Management AOD 9604 has been shown to stimulate lipolysis (the breakdown of fat) and inhibit lipogenesis (the formation of new fat), potentially aiding in fat loss and weight management. Targeted Fat Reduction The peptide may help reduce fat in specific areas, such as the abdominal region, by promoting the breakdown of stored fat. Improved Metabolism AOD 9604 may enhance metabolic rate, leading to increased calorie burning and potentially supporting weight loss efforts. Muscle Preservation Unlike some weight loss methods, AOD 9604 may help preserve lean muscle mass during fat loss, contributing to improved body composition. Bone and Cartilage Repair Some studies suggest that AOD 9604 may have regenerative properties, potentially aiding in the repair of bone and cartilage tissue. Enhanced Exercise Recovery The peptide may support faster recovery from exercise-induced muscle damage, reducing soreness and improving performance. ⚠️ Important Considerations Administration: AOD 9604 is typically administered via subcutaneous injection Dosage: Common dosing ranges from 300–500 mcg per day, depending on individual goals and protocols. Duration: Treatment cycles often last between 4 to 12 weeks, followed by breaks to assess effectiveness and reduce potential side effects. Consultation: It's crucial to consult with a healthcare professional before starting AOD 9604 therapy to ensure it's appropriate for your individual health needs and goals. AOD 9604 peptide therapy is considered a safe and effective solution for weight loss.

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Growth Hormone Secretagogues

Ipamorelin works by binding to IGF-1 receptors in the body and mimicking its effects on those receptors. This causes an increase in muscle mass and strength, as well as fat loss due to increased metabolism and lipolysis (the breakdown of fat). Semorelin + Ipamorelin (5mg/5mg) – Key Uses, Benefits & Protocol This growth hormone (GH)-stimulating peptide blend is used for anti-aging, fat loss, muscle growth, and recovery. 1. Primary Uses A. Anti-Aging & Longevity Boosts collagen → Improves skin elasticity, reduces wrinkles. Enhances sleep quality → Deepens REM sleep for cellular repair. Supports cognitive function → May improve memory/focus. B. Fat Loss & Metabolism Reduces stubborn fat (especially visceral/belly fat). Improves insulin sensitivity → Helps with metabolic disorders. C. Muscle Growth & Recovery Increases lean muscle mass (without water retention). Speeds up injury recovery (tendons, ligaments, joints). D. Performance Enhancement (Athletes/Bodybuilders) Enhances workout recovery → Less soreness, faster gains. Preserves muscle during cutting phases. 2. How It Works Sermorelin → Stimulates natural GH release from the pituitary. Ipamorelin → A selective GH secretagogue (avoids cortisol/prolactin spikes). Synergy: More sustained GH pulses than either peptide alone. (Unlike synthetic HGH, this combo promotes natural, balanced GH secretion.) 3. Dosage & Administration Standard Dose: 5mg Sermorelin + 5mg Ipamorelin per vial (mixed with bacteriostatic water). Daily Injection: 100-300mcg each (e.g., 100mcg Sermorelin + 100mcg Ipamorelin). Typically 1-2 injections/day (morning and/or before bed). Cycle Length: 8-12 weeks (then take a 4-week break). 4. Expected Results & Timeline 📌 4-6 Weeks: Better sleep, increased energy, reduced body fat. 📌 8-12 Weeks: Visible muscle tone, tighter skin, faster recovery. 📌 3+ Months: Long-term anti-aging benefits (if cycled properly). (Best paired with strength training + high-protein diet.) 7. Alternatives to Consider Peptide Best For Pros Cons Tesamorelin + Ipamorelin Fat loss (visceral) FDA-approved (for HIV lipodystrophy) Expensive Final Verdict ✅ Best for: Anti-aging (skin, cognition, longevity). Athletes seeking muscle growth + recovery. Men/women targeting stubborn fat. . Detailed Benefits & Science How it compares to HGH or other peptides (like CJC-1295). Anti-aging mechanisms (collagen, cellular repair). 2. Cycle Recommendations Optimal dosing (e.g., 100mcg vs. 300mcg per day). How long to run it (8 vs. 12 weeks). 5. Success Stories/User Experiences Real-world results for fat loss, muscle gain, or skin improvement. Increased energy levels: sermorelin and ipamorelin help boost energy and stamina, allowing you to feel more active and engaged throughout the day. Improved sleep quality: By enhancing restorative sleep, sermorelin and ipamorelin can lead to better overall health and well-being. Sermorelin is a peptide hormone that is structurally similar to growth hormone-releasing hormone (GHRH). It is typically used to treat growth hormone deficiency in children and adults. It can also be used for other conditions, such as improving wound healing, reducing fat mass, and increasing muscle mass. Sermorelin and Ipamorelin peptides are often combined because they have synergistic properties. Research has proven them to help slow down the aging process, increase muscle mass, decrease fat mass, reduce inflammation, heal the gut and more. How often should I take Sermorelin? A dosage of 0.2-0.3 mcg once daily at bedtime by subcutaneous injection is recommended. Ipamorelin is a peptide that has been shown to increase growth hormone levels in humans by stimulating the hypothalamus, which is responsible for regulating the secretion of growth hormone. Ipamorelin works by binding to IGF-1 receptors in the body and mimicking its effects on those receptors. This causes an increase in muscle mass and strength, as well as fat loss due to increased metabolism and lipolysis (the breakdown of fat). When Can I Expect To See Results? While patients will notice some significant increases changes in the body after the first month, the full-benefits are usually fully noticed after three to six months of therapy. Month 1 * Increased energy * Improved stamina * Deeper, more restful sleep Month 2 * Improved skin, reduced wrinkles * Stronger nails and hair * Increased metabolism Month 3 * Enhanced sex drive and performance * Improved mental focus * Improved joint health Month 4 * Continued weight reduction * Improved skin elasticity * Increased lean muscle mass Month 5 * Noticeably fuller and healthier hair * Reduced appearance of wrinkles, better skin tone * Continued reduction in belly fat Month 6 * 5-10% reduction in body fat (without exercise/diet) * 10% increase in lean muscle mass * Improved vitality due to organ regrowth WE EXPORT TO USA WE EXPORT TO UK WE EXORT TO CANADA WE EXPORT TO SINGAPORE WE EXPORT

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