Generic / Brand Name TAFERO‑EM 25 mg (Fixed‑dose combination) Active Ingredients (per tablet) Emtricitabine (FTC) – 200 mg Tenofovir Alafenamide (TAF) – 25 mg (as Tenofovir alafenamide fumarate equivalent) Drug Class Antiretroviral agents – Nucleotide / nucleoside reverse transcriptase inhibitors (NtRTI & NRTI) Dosage Form & Strength Film‑coated tablet, strength: 200 mg + 25 mg Indications ‑ For treatment of Human Immunodeficiency Virus type‑1 (HIV‑1) infection in adults and adolescents (12 years or older; typically weighing ≥ 35 kg) as part of combination antiretroviral therapy (ART). Mechanism of Action Emtricitabine and Tenofovir alafenamide inhibit the HIV reverse transcriptase enzyme, blocking viral replication and lowering viral load. Administration Take orally. Do not chew, crush, or split the tablet. Tafero EM (200 mg Emtricitabine / 25 mg Tenofovir Alafenamide) is an antiviral tablet used to treat HIV-1 in adults and adolescents (35+ kg) and for Pre-Exposure Prophylaxis (PrEP) to reduce high-risk infection. It also treats chronic Hepatitis B (HBV) by stopping viral replication. Key Uses and Information HIV-1 Treatment & Prevention: Used as a combination antiretroviral therapy for HIV-1 and as PrEP to prevent infection in high-risk individuals. Chronic Hepatitis B: Indicated for the management of chronic Hepatitis B Virus (HBV) infection. Dosage: The standard dose is one tablet daily, taken with or without food. Mechanism: Works by inhibiting the reverse transcriptase enzyme, thereby stopping the virus from multiplying. Side Effects: Potential side effects include nausea, diarrhea, headache, fatigue, reduced bone density, and kidney issues. Precautions: It is crucial not to stop taking this medication without consulting a doctor, as this may worsen hepatitis. Treatment of HIV‑1 Infection TAFERO‑EM 25 mg is a fixed-dose combination antiretroviral medication. It contains Tenofovir alafenamide (25 mg) and Emtricitabine (200 mg). It is used as part of combination antiretroviral therapy (ART) to suppress HIV replication, reduce viral load, and prevent progression to AIDS. Suitable for adults and adolescents HIV Pre‑Exposure Prophylaxis (PrEP) – Off-label in some regions Some guidelines allow its use in high-risk HIV-negative individuals to reduce the chance of infection. Packaging & Storage Typically supplied as 30 tablets per pack. Store below 30 °C, in original container; protect from moisture.