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FoxO4-DRI 10mg Peptide Science |USES|DOSES| UNITED KINGDOM FAST DELIVERY Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ FoxO4-DRI = A powerful senolytic research peptide Acts via FoxO4-p53 disruption, promoting senescent cell apoptosis Highly promising in aging, neurodegeneration, and regenerative biology fields 🔬 1. Anti-Aging & Longevity Research Clears senescent cells, which accumulate with age and cause inflammation and tissue dysfunction. By removing these cells, FoxO4-DRI may slow biological aging and restore tissue function (based on animal studies). Shown to extend healthspan (not necessarily lifespan) in mice. 🧪 2. Cellular Rejuvenation Helps promote tissue regeneration and stem cell activation. May reverse signs of aging at the cellular level, especially in tissues like muscles, kidneys, and the brain. 🧠 3. Cognitive Health Studies in mice showed memory improvement and neural rejuvenation in aged animals after FoxO4-DRI treatment. Potential use in research for neurodegenerative diseases like Alzheimer’s or age-related cognitive decline. 🩺 4. Senolytic Therapy Research Works by disrupting the interaction between FoxO4 and p53, which causes senescent cells to undergo apoptosis (programmed cell death). May be combined in research with other senolytics like Dasatinib and Quercetin. BUY IN WORLD WIDE BUY IN UK, USA, UAE, SINGAPORE

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Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ NAD+ (Nicotinamide adenine dinucleotide), in a 100mg dose from Peptide Science, is used for a variety of potential benefits related to cellular health and function. These include supporting energy production, DNA repair, and combating the effects of aging. NAD+ plays a crucial role in numerous cellular processes, making it a subject of interest for both its potential therapeutic applications and its role in healthy aging. Energy Production: NAD+ is essential for the cellular energy production process, particularly in the mitochondria. It acts as a coenzyme, facilitating the transfer of electrons in redox reactions, which are crucial for ATP (energy) production. DNA Repair: NAD+ is a substrate for enzymes called PARPs, which play a vital role in repairing DNA damage. Maintaining sufficient NAD+ levels can help ensure proper DNA repair and genomic stability. ✅ Primary Uses of NAD⁺ (100mg) Cellular Energy Production NAD⁺ is essential for mitochondrial function, helping convert nutrients into ATP (energy). Often used to combat fatigue or low energy levels. Healthy Aging & Longevity NAD⁺ levels decline with age. Supplementation may support DNA repair, cellular health, and overall longevity via sirtuin activation (especially SIRT1). Cognitive Function May enhance brain health, memory, and focus by supporting neuronal function and reducing oxidative stress. Metabolic Support Helps regulate metabolism, insulin sensitivity, and weight management. May support healthy blood sugar levels. Addiction & Withdrawal Support (High-dose clinical setting) NAD⁺ IV therapy is sometimes used in detox programs to ease withdrawal symptoms and improve mental clarity. 100 mg is a low dose; IV protocols often use much higher amounts. Skin and Anti-Aging Products Included in some topical formulations to promote skin cell repair and reduce signs of aging. Sirtuin Activation: NAD+ is also required by sirtuins, a class of proteins involved in gene regulation, cellular stress responses, and potentially, longevity. Anti-Aging: Because NAD+ is involved in so many fundamental cellular processes, its decline with age is linked to various age-related changes. Maintaining NAD+ levels through supplementation is being explored as a way to potentially mitigate some of these changes and promote healthy aging.

The first 29 amino acids of GHRH were discovered to be as equally potent as its full 44 amino acid structure[1][2] This fragment became known as GRF (1-29). However, due to a rapid metabolic clearance analogues of GRF (1-29) were synthesized to enhance the biological activity and reduce the rapidity of metabolic clearance. These analogues were primarily created by substituting amino acids within the peptide structure for amino acids more resistant to enzymatic cleavage. One early analogue substituted the amino acid L-alanine (abbreviated as Ala or A) at the 2nd position of the peptide structure for its optical isomer (mirror image), D-alanine (abbreviated as D-Ala). This substitution resulted in a peptide bond between D-Ala and the 3rd amino acid in the structure aspartic acid (Asp) more able to resist rapid cleavage by the enzyme dipeptidyl peptidase-4, a cleavage which had previously led to an inactive peptide fragment.[3][4] This successful modification prompted the further creation of analogues with additional amino acid substitutions. Ipamorelin: A selective growth hormone secretagogue, Ipamorelin stimulates the release of GH by mimicking ghrelin's action on the ghrelin receptor. It is known for its specificity and minimal side effects compared to other GH-releasing peptides. Mod GRF 1-29 (CJC-1295 without DAC): This is a modified version of the first 29 amino acids of growth hormone-releasing hormone (GHRH). The modifications extend its half-life and enhance its ability to stimulate the pituitary gland to release GH. It is often used in research to study GH secretion patterns and related metabolic effects. ⚖️ Dosage and Composition The 5/5 mg blend indicates that each vial contains 5 mg of Mod GRF 1-29 and 5 mg of Ipamorelin, totaling 10 mg per vial. This combination is designed to provide a balanced stimulation of GH release, potentially offering synergistic effects when used in research protocols. 🔬 Research Applications In scientific studies, this peptide blend is utilized to: Study Growth Hormone Dynamics: Investigating the patterns and regulation of GH secretion. Metabolic Research: Understanding the role of GH in metabolism, including fat metabolism and muscle growth. Aging and Longevity Studies: Exploring the effects of GH on aging processes and potential therapeutic applications. Sleep and Recovery Research: Examining how GH influences sleep patterns and recovery processes. ⚠️ Important Considerations Research Use Only: These peptides are intended strictly for laboratory research and are not approved for human or veterinary use. Legal Status: The legality of purchasing and possessing these peptides varies by country and jurisdiction. It's essential to consult local regulations before acquiring them. Storage and Handling: Proper storage conditions are crucial to maintain peptide stability. Typically, lyophilized peptides should be stored at -20°C or colder and protected from light. Reconstitution should be done with appropriate solvents, and solutions should be stored at 4°C and used within a specified timeframe. Mod GRF 1-29 + Ipamorelin (5/5 mg) is primarily used in scientific research and clinical studies to investigate its effects on human growth hormone (GH) release and related metabolic functions. It is not FDA-approved for general medical use, but here are the commonly researched uses and potential applications: Stimulation of Growth Hormone (GH) Release Both peptides work synergistically to enhance the natural pulsatile release of GH from the pituitary gland. Mod GRF 1-29 initiates GH release, while Ipamorelin amplifies it by mimicking ghrelin. Anti-Aging Studies GH has regenerative effects on tissues, so researchers study this combo to explore its potential for: Improving skin elasticity Increasing energy levels Enhancing sleep quality Muscle Growth and Recovery (in studies) GH can help stimulate muscle protein synthesis and recovery. This combo is sometimes researched for its effects on lean muscle mass and exercise recovery. Fat Loss & Metabolic Support GH mobilizes stored fat, making this blend of interest in obesity and metabolic syndrome research. May support lipolysis (fat breakdown) in clinical models. Bone Density Studies GH supports bone mineralization. This combo is explored for potential applications in osteopenia/osteoporosis research. Sleep Improvement GH release is tied to deep sleep stages; researchers observe whether this combo improves sleep architecture and REM sleep. Modified GRF (1-29) acts to increase growth hormone production and release by binding to the growth-hormone-releasing hormone receptor (GHRHR) on cells in the anterior pituitary.

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