Brand Name: Rybelsus
Formulation: Oral tablet
Dosing: Once daily, taken on an empty stomach with water
Type 2 Diabetes Management (Primary Use)
Initial dose:
3 mg is used as a starting dose to allow the body to adjust to the medication.
It is not therapeutic on its own—patients are usually titrated to 7 mg or 14 mg for full glucose-lowering effect.
Helps lower blood sugar (HbA1c) in adults with Type 2 diabetes.
How It Works.
Semaglutide is a GLP-1 receptor agonist, which:
Stimulates insulin secretion (when glucose is high)
Reduces glucagon secretion
Slows gastric emptying
Reduces appetite (mildly at this dose)
DOSAGE :- Start at 0.25 mg once weekly. After 4 weeks, increase the dose to
0.5 mg once weekly. If after at least 4 weeks additional glycemic
control is needed, increase to 1 mg once weekly (2.1).
Administer once weekly at any time of day, with or without meals
If a dose is missed administer within 5 days of missed dose
Inject subcutaneously in the abdomen, thigh, or upper arm
Indications & Uses
Initial dose for Type 2 diabetes mellitus treatment (used for 30 days before titration to 7 mg or 14 mg)
Helps lower blood glucose (HbA1c)
Used in combination with diet and exercise
Wegovy (semaglutide) for weight loss
Wegovy (semaglutide) is used for weight loss and weight maintenance in patients 12 years and older with obesity
Used for reducing major cardiovascular event risks (such as heart attack, stroke, or death) in adults with type 2 diabetes with known heart disease
Injection is given 1 time a week
under the skin of the stomach (belly), the thigh, or the upper arm, using an autoinjector (pen)
This injection should be used in addition to a reduced-calorie diet and increased physical activity.