Sildenafil is used to treat men who have erectile dysfunction (also called sexual impotence). Sildenafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly.
How It Works
Sildenafil inhibits the PDE5 enzyme, which normally breaks down cGMP (a chemical that relaxes smooth muscles). By blocking PDE5, blood vessels in the penis relax and widen, allowing increased blood flow and facilitating an erection during sexual arousal.
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