RENOCRIT 4000 IU Injection is classified as an Erythropoiesis-Stimulating Agent (ESA) and an anti-anaemic medication. It contains Recombinant Human Erythropoietin Alfa, which mimics the body's natural hormone to stimulate bone marrow production of red blood cells, treating anaemia associated with chronic kidney disease (CKD), chemotherapy, and HIV treatment.
Key Details of Renocrit 4000 IU :
Pharmacological Category: Erythropoiesis-stimulating agents (ESAs).
Therapeutic Category: Anti-anaemic.
Chemical Class: Amino acids, peptides, and analogues.
Indications: Treatment of anemia in CKD, cancer patients on chemotherapy, and HIV patients on Zidovudine.
Administration: Intravenous (IV) or subcutaneous (SC) injection.
Common Side Effects: Hypertension, headache, nausea, fever, and flu-like symptoms.
How It Works :
Stimulates the bone marrow to produce more red blood cells.
Improves oxygen delivery to tissues and reduces symptoms like fatigue, weakness, and shortness of breath.
Renocrit contains a synthetic form of erythropoietin, a hormone that stimulates the bone marrow to produce red blood cells, helping improve oxygen transport and reduce symptoms of anemia.
(Active ingredient: Epoetin alfa 4000 IU per 0.4 ml)
Main Uses :
Anemia due to Chronic Kidney Disease (CKD)
Helps increase red blood cell count in patients on dialysis or not on dialysis.
Chemotherapy-Induced Anemia
Used in cancer patients whose hemoglobin drops due to chemotherapy.
HIV-Related Anemia
For patients taking antiretroviral therapy (e.g., zidovudine) who develop low hemoglobin.
Reduction of Blood Transfusions
Pre-surgery or in conditions with expected high blood loss, to reduce the need for red blood cell transfusions.
Therapeutic Uses :
Renocrit 4000 IU Injection is used to treat or manage anemia caused by:
Chronic kidney disease (CKD) – including patients on dialysis or non‑dialysis.
Anemia linked to cancer chemotherapy or cancer therapy.
Anemia in patients treated with certain antiretroviral drugs (e.g., zidovudine for HIV).
It may also be used to reduce the need for red blood cell transfusions before elective surgery in patients at high risk of blood loss.
Administration :
Route: Injected subcutaneously (under the skin) or intravenously (into a vein) under medical supervision.
Dosage: Determined by a doctor based on body weight, hemoglobin levels, and response to treatment.
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