Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Generic Name :- Kisspeptin-10 Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins 1. Stimulation of Gonadotropin-Releasing Hormone (GnRH) Kisspeptin-10 stimulates the hypothalamus to release GnRH, which then promotes the secretion of: Luteinizing hormone (LH) Follicle-stimulating hormone (FSH) This cascade is crucial for puberty onset, ovulation, and fertility regulation. 2. Fertility Research Used in assisted reproductive technologies (ART) and IVF studies to promote natural hormonal responses. Can potentially reduce the need for synthetic hormones like hCG. 3. Hypogonadism and Delayed Puberty Investigated as a treatment for hypogonadotropic hypogonadism (low LH/FSH due to low GnRH). May help restore reproductive function in affected individuals. 4. Polycystic Ovary Syndrome (PCOS) Studied for its role in correcting LH/FSH imbalances in PCOS patients. 5. Diagnostic Use Used to test pituitary function or the integrity of the hypothalamic-pituitary-gonadal (HPG) axis. BUY Kisspeptin-10 5mg IN CHEAP PRICE GET BEST OFFERS ON Kisspeptin-10 5mg FROM US SKYBLUE INTERNATIONAL

Gonadorelin 10mg , Peptide USA FAST DELIVERY Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ 1. 🎯 Diagnostic Testing of the HPG Axis Used to assess pituitary function by measuring LH/FSH response—helpful in diagnosing hypogonadism or pituitary disorders . 2. 👩‍🔬 Female Infertility & Ovulation Induction Triggers ovulation in women with irregular periods Widely used in IVF and ART, often combined with hCG, to improve ovarian response and implantation rates 3. 👨 Male Hypogonadism & Delayed Puberty Stimulates testosterone and spermatogenesis in male hypogonadotropic hypogonadism and delayed puberty Helps prevent testicular atrophy during TRT and promotes natural LH/FSH production 4. 🧬 Hormone-Sensitive Cancers (Experimental) Explored in breast and prostate cancer to suppress estrogen/testosterone over long-term use . 5. 🦴 Bone, Muscle & Metabolic Health (Research) Preliminary studies show benefits for bone density, muscle strength, mood, and metabolic function via hormone regulation . 6. 🧠 Neurological & Cognitive Research Emerging research on GnRH analogues for potential applications in Alzheimer's disease and cognitive health Diagnosing HPG axis function Boosting fertility and managing reproductive disorders Treating male hormonal deficiencies and puberty delay Evaluating emerging roles in cancer, veterinary fertility, bone/muscle health, and neurology FAST DELIVERY FOR USA FAST DELIVERY FOR UK FAST DELIVERY FOR CANADA FAST DELIVERY FOR AUSTRALIA FAST DELIVERY FOR ABU DHABI FAST DELIVERY FOR SINGAPORE

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FoxO4-DRI 10mg Peptide Science |USES|DOSES| UNITED KINGDOM FAST DELIVERY Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ FoxO4-DRI = A powerful senolytic research peptide Acts via FoxO4-p53 disruption, promoting senescent cell apoptosis Highly promising in aging, neurodegeneration, and regenerative biology fields 🔬 1. Anti-Aging & Longevity Research Clears senescent cells, which accumulate with age and cause inflammation and tissue dysfunction. By removing these cells, FoxO4-DRI may slow biological aging and restore tissue function (based on animal studies). Shown to extend healthspan (not necessarily lifespan) in mice. 🧪 2. Cellular Rejuvenation Helps promote tissue regeneration and stem cell activation. May reverse signs of aging at the cellular level, especially in tissues like muscles, kidneys, and the brain. 🧠 3. Cognitive Health Studies in mice showed memory improvement and neural rejuvenation in aged animals after FoxO4-DRI treatment. Potential use in research for neurodegenerative diseases like Alzheimer’s or age-related cognitive decline. 🩺 4. Senolytic Therapy Research Works by disrupting the interaction between FoxO4 and p53, which causes senescent cells to undergo apoptosis (programmed cell death). May be combined in research with other senolytics like Dasatinib and Quercetin. BUY IN WORLD WIDE BUY IN UK, USA, UAE, SINGAPORE

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+91 9529672584‬ ‪+91 7499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ SS-31 (25mg) :- SS-31, also known as elamipretide or Bendavia, is a mitochondria-targeting peptide that has shown potential in treating various conditions by improving mitochondrial function. It has been investigated for its antioxidant, anti-inflammatory, and anti-apoptotic properties, particularly in the context of neurodegenerative diseases, inflammatory diseases, and ischemia-reperfusion injury. SS-31 (also known as Elamipretide) is a synthetic peptide that targets and protects mitochondria, the energy-producing structures in cells. The 25 mg dose is commonly used in clinical trials and experimental protocols. Use Details 🫀 Heart Disease Improves heart function in heart failure and ischemic heart disease 🧠 Neurodegenerative Diseases May protect brain cells in conditions like Alzheimer’s, Parkinson’s 👁️ Eye Disorders Studied in dry age-related macular degeneration (dry AMD) 💪 Muscle Fatigue Helps with exercise intolerance and mitochondrial myopathy 🧬 Mitochondrial Dysfunction Repairs damaged mitochondria, boosts ATP production 🧫 Kidney Protection May reduce kidney injury in acute or chronic kidney disease 🧓 Age-Related Fatigue Improves mobility and stamina in older adults How It Works Targets mitochondria directly Binds to cardiolipin in the mitochondrial membrane Prevents oxidative damage Restores energy production (ATP) 💉 Common Dosage Form 25 mg usually administered subcutaneously (under the skin) once daily in studies. SS-31, also known as Elamipretide, is a synthetic peptide designed to improve mitochondrial function and reduce oxidative stress. It's primarily used to protect and restore mitochondrial function, specifically by reducing oxidative stress, stabilizing cardiolipin (a mitochondrial phospholipid), and improving mitochondrial energy production. Research suggests it may also be beneficial in conditions like Alzheimer's, brain injury, and kidney disease. The 25mg dosage refers to the amount of SS-31 in a single dose, often administered via injection. Mitochondrial Target: SS-31 specifically targets mitochondria, the powerhouses of cells, and is thought to protect and restore their function.

Contact Us on telegram or WhatsApp +917887449821‬ ‪+919168783773‬ ‪+91 9529672584‬ ‪+91 7499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ NAD+ (1000mg) NAD+ (1000mg) is often used to address age-related decline in energy levels, cognitive function, and overall vitality. It's also explored for its potential benefits in athletic performance, addiction recovery, and even in mitigating some aspects of neurodegenerative diseases. 🔋 Cellular Energy Production Boosts ATP synthesis in mitochondria. Reduces chronic fatigue and improves physical stamina. Often used by athletes or people with low energy disorders. Anti-Aging & Longevity Activates sirtuins (SIRT1–SIRT7), which: Promote DNA repair Improve mitochondrial health Extend cell lifespan NAD⁺ levels naturally decline with age; high doses help restore youthful levels. Cognitive Enhancement & Brain Health Supports neuroplasticity, memory, and focus. May help in early-stage neurodegenerative conditions like Alzheimer’s or Parkinson’s (as part of a broader protocol). Protects neurons from oxidative stress and inflammation. Addiction Recovery & Detox Support Used in IV NAD⁺ therapy clinics (usually 1000–3000 mg IV per session) to: Reduce withdrawal symptoms from alcohol, opioids, stimulants Improve mental clarity during recovery Oral NAD⁺ (1000 mg) may complement recovery efforts when IV isn't available. Energy and Metabolism: NAD+ is essential for cellular energy production, particularly in the mitochondria. Boosting NAD+ levels can improve energy production, leading to increased stamina and reduced fatigue. This can be beneficial for individuals experiencing age-related energy decline or those seeking to enhance athletic performance. BUY IT FROM US https://www.skyblueinternationals.com/

TADALAFIL & DAPOXETINE EXTRA SUPER VIDALISTA 100mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, UK, EUROPE, UAE & GET 20% OFF ON BULK ORDER Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ Erectile Dysfunction (ED) Tadalafil (PDE‑5 inhibitor) relaxes penile blood vessels, improving erections during sexual stimulation Premature Ejaculation (PE) Dapoxetine (an SSRI) delays ejaculation, boosting control and satisfaction Dosage & How to Use: Available in strengths like 40 mg tadalafil + 60 mg dapoxetine or 60 mg + 30 mg, and 80 mg + 40 mg. Take 1 tablet orally about 30–60 minutes before sex, not more than once in 24 hours Can be taken with or without food; avoid alcohol, grapefruit juice, and heavy meals Additional Benefits Dual-action therapy—simultaneously tackles ED and PE to improve overall sexual health and satisfaction. Extended performance window—tadalafil effect may last up to 36 hours, while dapoxetine adds ejaculatory control BUY IT NOW

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