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Diabetes & chronic weight management

TIZARO TIRZEPATIDE 12.5mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Tirzepatide is FDA-approved to improve blood sugar (glucose) control in adults with type 2 diabetes, as an adjunct to diet and exercise. It is a once-weekly injectable medication. It works as a dual GIP and GLP-1 receptor agonist, enhancing insulin secretion, reducing glucagon levels, and slowing gastric emptying. It helps lower HbA1c and postprandial glucose levels. Although initially approved for type 2 diabetes, tirzepatide is also being used and studied for weight loss, especially under the brand name Zepbound (approved by the FDA in 2023 for chronic weight management). It is prescribed for people who are: Obese (BMI ≥30), or Overweight (BMI ≥27) with at least one weight-related condition (e.g., hypertension, type 2 diabetes, dyslipidemia). It reduces appetite and calorie intake significantly. 12.5 mg is typically a step-up dose. Patients usually start at a lower dose (e.g., 2.5 mg or 5 mg) and gradually increase every 4 weeks to minimize gastrointestinal side effects. 12.5 mg may be a maintenance or transitional dose toward the maximum dose of 15 mg/week, depending on individual tolerance and treatment goals. Generic Name Tirzepatide Brand Names Mounjaro (for diabetes), Zepbound (for weight loss) Dose Strength 12.5 mg Dosage Form Prefilled pen (subcutaneous injection) Route of Administration Subcutaneous (SC) – once weekly Appearance Clear, colorless to slightly yellow solution TIRZEPATIDE 12.5mg AVAILABLE IN INDIA AT BEST PRICE. https://www.skyblueinternationals.com/ LOOKING FOR GENERIC MEDICINES ??? https://www.skyblueinternationals.com/ TIRZEPATIDE 12.5mg AT LOWEST PRICE TIRZEPATIDE 12.5mg IN STOCK TIRZEPATIDE 12.5mg SHIPPING WORLD WIDE

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Diabetes & chronic weight management

TIZARO TIRZEPATIDE 2.5mg BUY IN USA, CANADA, SINGAPORE, AUSTRALIA Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Type 2 Diabetes Management TIZARO 2.5mg is used alongside diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It enhances insulin secretion and reduces glucagon levels in a glucose-dependent manner. Additionally, it improves insulin sensitivity, aiding in more effective glucose utilization . Weight Management While not officially approved for weight loss, tirzepatide has shown potential in reducing body weight. It may suppress appetite, slow gastric emptying, and increase satiety, which can be beneficial for overweight individuals, particularly those with metabolic disorders Enhancing glucose-dependent insulin secretion Suppressing glucagon Improving insulin sensitivity Delaying gastric emptying to control blood sugar levels Chronic Weight Management Approved for obesity and overweight individuals with comorbidities, due to its: Appetite suppression and increased satiety Slower gastric emptying Significant fat and weight loss demonstrated in clinical trials Cardiovascular & Metabolic Benefits Lowers blood pressure and improves lipid profile Reduces inflammatory markers linked to metabolic syndrome Dosage Details (2.5 mg) Starting dose: 2.5 mg subcutaneous injection once weekly for approximately 4 weeks to minimize GI side effects Administration sites: Abdomen, thigh, or upper arm; consistent day each week BUY NOW FROM US WITH BEST DEALS & OFFERS

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Miscellaneous Peptides

Melanotan-2 10mg, Peptide BUY IN CANADA, SINGAPORE, AUSTRALIA Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪ +917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ ✅ 1. Tanning Agent Primary use: Promotes skin darkening (tanning) by stimulating melanocytes to produce melanin. Users report a deeper, longer-lasting tan with less UV exposure (sunlight or tanning beds). Often used cosmetically to achieve a bronzed look while reducing skin cancer risk from prolonged sun exposure. ✅ 2. Libido Enhancement MT-II stimulates the hypothalamus, increasing libido and erectile function in some users. Studied as a potential treatment for erectile dysfunction (ED), especially where PDE5 inhibitors (like Viagra) are ineffective. ✅ 3. Fat Loss (Anecdotal) Some users report appetite suppression and increased fat metabolism, but scientific evidence is limited. These effects are likely secondary to central nervous system activity. Product Name Melanotan II (Melanotan-2, MT-II) Molecular Weight 1024.18 g/mol Peptide Purity ≥ 98% (HPLC) Appearance White to off-white lyophilized powder A full vial is usually 10mg, reconstituted with bacteriostatic water. Typical research dosing: Start low: 250–500 mcg/day (0.25–0.5mg) subcutaneously. Build up slowly to minimize side effects. Most users don’t exceed 1mg/day. Tanning agent Stimulates melanin for darker skin Libido enhancer Increases arousal and erectile response Appetite suppression May reduce food intake (anecdotal) BUY IN CANADA BUY IN SINGAPORE BUY IN AUSTRALIA BUY IN USA BUY IN ABU DHABI

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Metabolic & Weight Management Peptides

Contact Us on telegram or WhatsApp +917887449821 +919168783773 +91 9529672584 +91 7499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://wa.me/c/917499402610 Name Semaglutide Purity ≥98% (as tested by HPLC, High-Performance Liquid Chromatography) CAS Number 910463-68-2 Molecular Formula C₁₈₇H₂₉₁N₄₅O₅₉ Molecular Weight ~4113.58 g/mol Peptide Sequence Modified GLP-1 (7-37) analog with substitutions to enhance stability Form Lyophilized powder (freeze-dried) Content 3mg per vial Semaglutide is a medication originally developed for type 2 diabetes and obesity treatment. It's a GLP-1 receptor agonist, meaning it mimics the hormone GLP-1, which helps regulate blood sugar and appetite. Type 2 Diabetes Management Lowers blood sugar by increasing insulin release and reducing glucagon secretion. Helps patients achieve better glycemic control. Weight Loss (Obesity or Overweight with Comorbidities) Reduces appetite and slows gastric emptying. FDA-approved under the brand name Wegovy for chronic weight management. 💉 Semaglutide 3mg – Dosing Guide (Research and Clinical Context) ✅ Clinically Approved Dosing (Prescription Use) Under brand names like Ozempic (for diabetes) and Wegovy (for weight loss), the FDA-approved semaglutide dosing follows this gradual titration to minimize side effects: Week Dose (Subcutaneous Injection) Weeks 1–4 0.25 mg once weekly Weeks 5–8 0.5 mg once weekly Weeks 9–12 1.0 mg once weekly (maintenance or increase as needed) Weeks 13+ 1.7 mg – 2.4 mg weekly (Wegovy max) or up to 2.0 mg (Ozempic max) Route: Subcutaneous injection (abdomen, thigh, or upper arm) Frequency: Once per week, same day/time ⚠️ Important Notes Side Effects: Can include nausea, vomiting, diarrhea, abdominal pain, and risk of pancreatitis. Not for Type 1 Diabetes or Ketoacidosis. Only certain brands and dosages are approved for specific uses.

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Metabolic & Weight Management Peptides

Semaglutide 3mg USES Brand Name: Rybelsus Formulation: Oral tablet Dosing: Once daily, taken on an empty stomach with water Type 2 Diabetes Management (Primary Use) Initial dose: 3 mg is used as a starting dose to allow the body to adjust to the medication. It is not therapeutic on its own—patients are usually titrated to 7 mg or 14 mg for full glucose-lowering effect. Helps lower blood sugar (HbA1c) in adults with Type 2 diabetes. How It Works. Semaglutide is a GLP-1 receptor agonist, which: Stimulates insulin secretion (when glucose is high) Reduces glucagon secretion Slows gastric emptying Reduces appetite (mildly at this dose) DOSAGE :- Start at 0.25 mg once weekly. After 4 weeks, increase the dose to 0.5 mg once weekly. If after at least 4 weeks additional glycemic control is needed, increase to 1 mg once weekly (2.1).  Administer once weekly at any time of day, with or without meals  If a dose is missed administer within 5 days of missed dose  Inject subcutaneously in the abdomen, thigh, or upper arm Indications & Uses Initial dose for Type 2 diabetes mellitus treatment (used for 30 days before titration to 7 mg or 14 mg) Helps lower blood glucose (HbA1c) Used in combination with diet and exercise Wegovy (semaglutide) for weight loss Wegovy (semaglutide) is used for weight loss and weight maintenance in patients 12 years and older with obesity Used for reducing major cardiovascular event risks (such as heart attack, stroke, or death) in adults with type 2 diabetes with known heart disease Injection is given 1 time a week under the skin of the stomach (belly), the thigh, or the upper arm, using an autoinjector (pen) This injection should be used in addition to a reduced-calorie diet and increased physical activity

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Metabolic & Weight Management Peptides

Retatrutide 16mg is being developed to target multiple metabolic conditions, with its primary uses in obesity management, type 2 diabetes, and fatty liver disease. Retatrutide is an investigational triple hormone receptor agonist (GLP-1, GIP, and glucagon receptors) Main Uses of Retatrutide 1. Obesity Treatment Primary target: Adults with obesity (BMI ≥30) or overweight (BMI ≥27) with a weight-related condition. Effectiveness: Up to 24.2% body weight loss at the highest tested dose (12 mg) over 48 weeks. Outperformed semaglutide (Wegovy) and tirzepatide (Zepbound) in trials. Mechanism: Appetite suppression Slowed gastric emptying Increased energy expenditure Type 2 Diabetes Management Improves blood glucose control by: Enhancing insulin sensitivity Increasing insulin secretion Reducing glucagon levels (in a glucose-dependent way) Massive reductions in liver fat (up to 82.4% in some patients) Helps improve: Liver enzyme profiles (ALT, AST) Hepatic insulin resistance SKYBLUE INTERNATIONAL is a trusted global pharmaceutical export company specializing in the export of high-quality medicines. With a strong commitment to healthcare excellence, we supply a wide range of branded and generic medicines to countries including the USA, UK, Australia, UAE, Canada, Singapore, and the Philippines. Our focus is on reliability, compliance, and timely delivery to meet the global demand for affordable and effective medical solutions. Medicine 💊 Retatrutide (16mg) BUY FROM SKYBLUE INTERNATIONAL Weight reduction Improved insulin sensitivity Hormonal balancing

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Pharmaceutical Tablets

PREGALYV 75 MG, PREGABALIN Capsules Pregaliv 75 Tablet SR is a prescription medicine used for the treatment of neuropathic pain. It decreases pain by modulating calcium channel activity of the nerve cells. This medicine also protects nerve fibers and heal damaged nerve cells. Pregaliv 75 Tablet SR is taken by mouth with or without food, preferably at bedtime. It is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as this is a habit-forming medicine. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor. Some common side effects of this medicine include nasopharyngitis, increased appetite, euphoric mood, tremor, blurred vision, dry mouth, dizziness, and sleepiness. Do not drive or do anything that requires mental focus until you know how this medicine affects you. The side effects are mild in nature and get improve with time. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. ⚙️ How It Works Pregabalin, the active ingredient, binds to calcium channels in the central nervous system, inhibiting excitatory neurotransmitter release. This action helps in reducing abnormal electrical activity in the brain and alleviates pain by calming overactive nerves. ⚠️ Side Effects Common Side Effects: Dizziness Drowsiness Dry mouth Weight gain Swelling of hands or feet Blurred vision Difficulty concentratingWellness Forever+1Wellness Forever+1 Serious Side Effects: Severe allergic reactions (e.g., trouble breathing, swelling of the face or throat) Mood or mental changes (e.g., depression, suicidal thoughts) Unusual fatigue or weakness Vision problems If you experience any of these serious side effects, seek medical attention promptly. ⚠️ Warnings & Precautions Allergic Reactions: Do not take Pregalyv 75 mg if you are allergic to pregabalin or any other ingredients. Pregnancy & Breastfeeding: Consult your doctor before use during pregnancy or breastfeeding. Kidney Function: Use with caution in patients with kidney problems; dosage adjustments may be necessary. CNS Effects: May cause dizziness, drowsiness, and blurred vision. Avoid activities requiring full alertness until you know how the medication affects you. Alcohol Interaction: Avoid alcohol as it can increase the risk of side effects like drowsiness and dizziness.

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Ivermectin Tablets

Get 25% OFF Iverguard ivermectin 15mg BUY in CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ Ivermectin is used to treat river blindness (onchocerciasis), intestinal infection from threadworms (strongyloidiasis), and other kinds of worm infections. Ivermectin is an anthelmintic. It works by interfering with the nerve and muscle functions of worms, by paralyzing and killing them. Primary Uses (Human, Parasitic Infections) Strongyloidiasis (threadworm) – Treats Strongyloides stercoralis infections in the intestines. Onchocerciasis (river blindness) – Targets Onchocerca volvulus, reducing microfilariae levels in skin and eyes Other Intestinal Helminths – Helps treat various roundworm infestations, such as ascariasis and enterobiasis, typically in mass-treatment settings.

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Diabetes & chronic weight management

ELITE TIRZEPATIDE 120mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Type 2 Diabetes Mellitus Main FDA-approved indication (as Mounjaro). Improves blood sugar control by: Increasing insulin secretion. Reducing glucagon (a sugar-raising hormone). Slowing gastric emptying. Chronic Weight Management Approved under brand name Zepbound in the U.S. Used in adults with: BMI ≥30 (obesity), or BMI ≥27 with weight-related conditions (like hypertension, high cholesterol, PCOS). Form: A multi-dose prefilled pen or vial designed for repeated subcutaneous use. This contrasts with single-dose pens (available in fixed-dose strengths like 5, 10, 15 mg) Content: Total of up to 120 mg of tirzepatide per pen/vial (commonly seen in compounded products) It's cost-effective (multiple doses in one pen). Allows customized weekly dosing (e.g. 7.5mg, 10mg, 12.5mg, 15mg). Often compounded by pharmacies for people needing dose flexibility. MULTI USE PEN ADJUSTABLE PEN BUY NOW WORLD WIDE SHIPPING AVAILABLE

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