'mimicking gut hormones'

TIZARO TIRZEPATIDE 12.5mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Type 2 Diabetes Management: Tizaro is prescribed to improve blood sugar control in adults with type 2 diabetes, as an adjunct to diet and exercise. Weight Loss: It is also used for weight loss in adults with obesity or overweight, sometimes with weight-related conditions. Tirzepatide, the active ingredient in Tizaro, is a dual GIP and GLP-1 receptor agonist. It mimics the actions of these gut hormones, which regulate blood sugar levels and appetite. Administration: Tizaro is injected under the skin (subcutaneously). It is typically administered once a week. Patients should be instructed on proper injection techniques. Tizaro (Tirzepatide) 15mg is a prescription injection used to manage type 2 diabetes and also for weight loss in adults. It works by mimicking gut hormones that help regulate blood sugar and appetite. It is administered once weekly via subcutaneous injection. BUY FROM US WORLD WIDE SHIPPING WITH GOOD PACKAGING CONTACT US FOR BEST OFFERS & DEALS

Tirzepatide (60mg) FAST DELIVERY TO FLORIDA Contact Us on telegram or WhatsApp +917887449821 +919168783773 +91 9529672584 +91 7499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Tirzepatide (60mg) Uses: Type 2 Diabetes: Tirzepatide is used to improve blood sugar control in adults with type 2 diabetes, often used with diet and exercise. Weight Management: It is also used for weight loss, particularly in adults who are overweight or obese, or who have weight-related medical problems. a synthetic peptide, a dual agonist for both GLP-1 (glucagon-like peptide 1) and GIP (glucose-dependent insulinotropic polypeptide) receptors. It is used to treat type 2 diabetes and may also be used for weight management. It works by mimicking the effects of two hormones involved in glucose regulation and appetite control, helping to lower blood sugar levels and potentially leading to weight loss. Tirzepatide is administered as a once-weekly subcutaneous injection. Dual Action: Tirzepatide targets both GLP-1 and GIP receptors, enhancing insulin sensitivity and potentially leading to weight loss. Mechanism of Action: It increases insulin secretion when blood sugar is high, lowers liver glucose production, and slows down food movement through the digestive tract, contributing to blood sugar control and weight loss. Administration: Tirzepatide is a subcutaneous injection, given once weekly. Potential Side Effects: Common side effects include nausea, vomiting, diarrhea, and constipation, especially during the initial dose escalation phase. Top Benefits of Tirzepatide :- Powerful Blood Sugar Control (Type 2 Diabetes) Lowers HbA1c levels significantly (up to 2.4% reduction) Helps regulate insulin and glucagon more effectively than GLP-1 drugs alone Outperforms other drugs like semaglutide and insulin degludec in trials

TO BUY Tirzepatide (40mg) Contact Us on telegram or WhatsApp +917887449821 +919168783773 +91 9529672584 +91 7499402610 Mail :- skyblueinternational033@gmail.com Internationalskyblue@gmail.com Viwe our catalog :- https://wa.me/c/917499402610 Tirzepatide is a dual agonist for the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors. The drug leads to significantly improved glycemic control and weight reduction in patients with T2DM, maximizing benefits similar to GLP-1 medications such as semaglutide. Tirzepatide (Zepbound brand) is used for weight loss, to help lose weight and keep weight off. Tirzepatide works for weight loss by decreasing appetite and slowing the movement of food from the stomach into the small intestine, which may make you feel full more quickly and for a longer period. The Zepbound brand of tirzepatide is also used for moderate to severe obstructive sleep apnea (OSA) in adults with obesity. Tirzepatide is a once-weekly injection given under the skin using a pen (autoinjector). Zepbound (tirzepatide) is FDA-approved for weight loss in adults with obesity or who are overweight and have weight-related medical problems or OSA. Zepbound helps you to lose weight and maintain weight loss and should be combined with diet and exercise. Tirzepatide (Mounjaro brand) is used for type 2 diabetes to help improve blood sugar levels. In type 2 diabetes, tirzepatide decreases blood sugar levels by helping release insulin when blood sugar levels are high, lowering the amount of sugar the liver makes, and slowing food movement through the intestines. Mounjaro should be used together with diet and exercise. Mounjaro (tirzepatide) is FDA-approved to treat adults with type 2 diabetes and should be used together with diet and exercise. It can be used as a single therapy (on its own) or with other diabetes medicines, including sulfonylureas, SGLT2 inhibitors, or metformin. It is not known if tirzepatide can be used in people who have had pancreatitis. Tirzepatide should not be used in people who have type 1 diabetes. Normally, when we eat, natural hormones called GIP and GLP-1 are released by the gut. These hormones increase insulin release, suppress appetite, slow gastric emptying, and increase the feeling of fullness. Tirzepatide works like our natural hormones GIP and GLP-1 by activating the GIP and GLP-1 receptors. Tirzepatide is a GIP and GLP-1 receptor agonist. Tirzepatide works (mechanism of action) by activating both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors. Weight Loss Achieved: tirzepatide: 64.6% of participants lost 15% of their weight semaglutide: 40.1% of participants lost 15% of their weighT Tirzepatide (40mg) USE FOR WEIGHT LOSS Mechanisms: Increases insulin release in response to glucose Reduces glucagon secretion Slows digestion to avoid sugar spikes

Hormones and Steroid API Hormones and Steroid API Composition Testosterone Enanthate Raw Powder USAGE:- Testosterone Enantate is a manufactured version of the naturally occurring male sex hormone, testosterone. It is used in adult men for testosterone replacement to treat various health problems caused by a lack of testosterone (male hypogonadism). Testosterone Enanthate Raw Powder USA FAST DELIVERY Florida Raw Powder IN INDIA Florida low price Florida Testosterone Enanthate Testosterone Enanthate USA FAST DELIVERY Georgia Raw Powder cheapest RAW POWDER IN INDIA Testosterone Enanthate Raw Powder we expo rt in USA Testosterone Enanthate Raw Powder we export to Alabama, Alaska, Arizona, Arkansas, California, ColoradO, Connecticut, Delaware, Florida, Georgia, Hawaii, Idaho, Illinois, Indiana, Iowa, Kansas, Kentuck, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin, Wyoming. Testosterone Enanthate raw powder we export in UK Testosterone Enanthate raw powder we export to London, Birmingham, Manchester, Liverpool, Leeds, Sheffield, Bradford, Bristol, Coventry, Nottingham, Newcastle upon Tyne, Oxford, Cambridge, York, Wakefield, Sunderland, Stoke-on-Trent, Southampton, Sheffield, Salford, Salisbury, Ripon, Truro, Wells, Westminster, Winchester, Wolverhampton, Worcester, Edinburgh, Glasgow, Aberdeen, Dundee, Inverness, Perth, Stirling, Dunfermline, Cardiff, Swansea, Newport, Bangor, St Asaph, St Davids, Wrexham, Belfast, Armagh, Londonderry, Lisburn, Newry, Bangor, Douglas, Hamilton, City of Gibraltar, Stanley, Jamestown. Testosterone Enanthate Raw Powder we export in UAE Testosterone Enanthate Raw Powder we export to Abu Dhabi, Al Ain, Al Dhannah, Madinat Zayed, Liwa Oasis, Ghayathi, Ar Ruways, Dubai, Jebel Ali, Hatta, Al Aweer, Al Marmoom, Sharjah, Khor Fakkan, Dibba Al-Hisn, Kalba, Al Dhaid, Mleiha, Al Saja'a, Ajman, Masfout, Umm Al Quwain, Al Sufouh, Ras Al Khaimah, Al Jazirah Al Hamra, Ar-Rams , Fujairah, Dibba Al-Fujairah, Masafi. Testosterone Enanthate USA FAST DELIVERY Georgia Raw Powder Testosterone Enanthate Raw Powder we export in SINGAPORE Testosterone Enanthate Raw Powder we export to Bishan, Bukit Merah, Bukit Panjang, Bukit Timah, Central Water Catchment, Chinatown, Downtown Core, Geylang, Kallang, Marina East, Marina South, Newton, Orchard, Outram, Queenstown, River Valley, Rochor, Singapore River, Southern Islands, Straits View, Tanglin, Toa Payoh, Bedok, Changi, Changi Bay, Changi Village, East Coast, Pasir Ris, Tampines, Simei, Upper East Coast, Admiralty, Kranji, Lim Chu Kang, Mandai, Sungei Kadut,. Woodlands, Yishun, Ang Mo Kio, Hougang, Kovan, Punggol, Sengkang, Serangoon, Boon Lay, Bukit Batok, Bukit Panjang, Choa Chu Kang, Clementi, Jurong East, Jurong West, Tengah, Tuas, Western Islands, Western Water Catchment.

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Generic Name :- Kisspeptin-10 Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins 1. Stimulation of Gonadotropin-Releasing Hormone (GnRH) Kisspeptin-10 stimulates the hypothalamus to release GnRH, which then promotes the secretion of: Luteinizing hormone (LH) Follicle-stimulating hormone (FSH) This cascade is crucial for puberty onset, ovulation, and fertility regulation. 2. Fertility Research Used in assisted reproductive technologies (ART) and IVF studies to promote natural hormonal responses. Can potentially reduce the need for synthetic hormones like hCG. 3. Hypogonadism and Delayed Puberty Investigated as a treatment for hypogonadotropic hypogonadism (low LH/FSH due to low GnRH). May help restore reproductive function in affected individuals. 4. Polycystic Ovary Syndrome (PCOS) Studied for its role in correcting LH/FSH imbalances in PCOS patients. 5. Diagnostic Use Used to test pituitary function or the integrity of the hypothalamic-pituitary-gonadal (HPG) axis. BUY Kisspeptin-10 5mg IN CHEAP PRICE GET BEST OFFERS ON Kisspeptin-10 5mg FROM US SKYBLUE INTERNATIONAL

BPC-157 + TB-500 (5/5mg) FAST DELIVERY INFLORIDA Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Component Quantity per vial BPC-157 5 mg TB-500 5 mg Total 10 mg Injury Recovery Accelerates healing of muscle, tendon, ligament, and joint injuries. May reduce downtime after sports injuries or surgeries. Chronic Inflammation or Pain Can be used to address chronic conditions like tendinitis, arthritis, and back pain. BPC-157 in particular has anti-inflammatory effects. Post-Surgical Healing Used to speed up tissue regeneration post-surgery. Gastrointestinal Disorders BPC-157 helps with IBS, Crohn’s, ulcers, and leaky gut syndrome. Performance Recovery Used by athletes and bodybuilders for faster recovery from training and to reduce risk of injury.

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+91 9529672584‬ ‪+91 7499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ BPC-157 (10mg) BPC 157, a pentadecapeptide derived from human gastric juice, has been demonstrated to promote the healing of different tissues, including skin, muscle, bone, ligament and tendon in many animal studies. However, the underlying mechanism has not been fully clarified. BPC-157 (10 mg) is a higher-dose vial of the Body Protective Compound-157, used for the same purposes as the 5 mg version—but typically more convenient for longer cycles, higher doses, or multi-site injuries. 🦴 1. Muscle, Tendon, Ligament, and Joint Repair Speeds healing from injuries: strains, tears, sprains, surgeries Often used by athletes recovering from rotator cuff tears, knee injuries, or Achilles tendonitis Can be injected near the injury or taken systemically 🧠 2. Nerve Healing & Neuroprotection Supports regeneration of damaged peripheral nerves May assist in recovery from nerve crush injuries or neuropathy Early animal studies show neuroprotective effects in traumatic brain injury models 🧪 3. Gastrointestinal Repair One of the most effective peptides for gut healing Used in: Leaky gut IBS / IBD (Crohn’s, ulcerative colitis) Gastric ulcers NSAID-induced intestinal damage 🧘‍♂️ 4. Anti-Inflammatory Effects Reduces chronic systemic inflammation Supports reduction of oxidative stress Can improve pain, swelling, and mobility in injured or inflamed tissues 🔁 5. Wound Healing & Skin Regeneration Applied (sometimes topically or injected near wound) to accelerate healing of: Cuts and abrasions Post-surgical wounds Burns 🏋️‍♂️ 6. Athletic Recovery & Performance Used in biohacking and performance enhancement protocols Shortens recovery time between workouts Helps prevent overuse injuries ⚙️ Why Use a 10 mg Vial? More convenient for: Longer treatment cycles (2–6 weeks) Larger body weight or higher dosing needs Multiple injury sites (e.g., knee + shoulder) Reduces frequency of reconstitution BPC-157 (10mg) IS AVAILABLE

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+91 9529672584‬ ‪+91 7499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ BPC-157 (5mg) :- Abstract. BPC 157, a pentadecapeptide derived from human gastric juice, has been demonstrated to promote the healing of different tissues, including skin, muscle, bone, ligament and tendon. Full Name: Body Protective Compound-157 Source: Derived from a protein found in human gastric juice Molecular Weight: ~1,419 Da Form: Synthetic peptide, usually as a 5 mg lyophilized powder BPC-157 is FDA-approved but is widely studied in animal models and used off-label in sports medicine, biohacking, and functional medicine. 1. 🦴 Tendon, Ligament, and Muscle Healing Accelerates repair of torn tendons and ligaments (e.g. ACL, rotator cuff) Supports muscle regeneration after injury or surgery Enhances collagen synthesis and angiogenesis 2. 🧘‍♂️ Joint & Cartilage Repair Used in cases of arthritis, joint pain, and cartilage degeneration May protect chondrocytes and stimulate cartilage regeneration 3. 🧠 Neurological and Nerve Healing Promotes recovery of damaged peripheral nerves Shown to help in cases of traumatic brain injury (TBI) and nerve crush injuries (animal data) 4. 🧪 Gut Health Extremely effective in healing the GI tract Used for: IBD (Crohn’s, ulcerative colitis) Leaky gut syndrome Gastric ulcers NSAID-induced damage 5. 🔥 Anti-Inflammatory & Cytoprotective Reduces systemic inflammation and oxidative stress Protects cells from toxins, ischemia, and stress damage 6. 💉 Wound Healing & Skin Repair Speeds up recovery of burns, cuts, and abrasions May improve scarring and skin regeneration 7. 💪 Performance & Recovery Used by athletes to speed recovery from training or injury May help mitigate damage from overtraining BUY IT FROM US https://www.skyblueinternationals.com/

The first 29 amino acids of GHRH were discovered to be as equally potent as its full 44 amino acid structure[1][2] This fragment became known as GRF (1-29). However, due to a rapid metabolic clearance analogues of GRF (1-29) were synthesized to enhance the biological activity and reduce the rapidity of metabolic clearance. These analogues were primarily created by substituting amino acids within the peptide structure for amino acids more resistant to enzymatic cleavage. One early analogue substituted the amino acid L-alanine (abbreviated as Ala or A) at the 2nd position of the peptide structure for its optical isomer (mirror image), D-alanine (abbreviated as D-Ala). This substitution resulted in a peptide bond between D-Ala and the 3rd amino acid in the structure aspartic acid (Asp) more able to resist rapid cleavage by the enzyme dipeptidyl peptidase-4, a cleavage which had previously led to an inactive peptide fragment.[3][4] This successful modification prompted the further creation of analogues with additional amino acid substitutions. Ipamorelin: A selective growth hormone secretagogue, Ipamorelin stimulates the release of GH by mimicking ghrelin's action on the ghrelin receptor. It is known for its specificity and minimal side effects compared to other GH-releasing peptides. Mod GRF 1-29 (CJC-1295 without DAC): This is a modified version of the first 29 amino acids of growth hormone-releasing hormone (GHRH). The modifications extend its half-life and enhance its ability to stimulate the pituitary gland to release GH. It is often used in research to study GH secretion patterns and related metabolic effects. ⚖️ Dosage and Composition The 5/5 mg blend indicates that each vial contains 5 mg of Mod GRF 1-29 and 5 mg of Ipamorelin, totaling 10 mg per vial. This combination is designed to provide a balanced stimulation of GH release, potentially offering synergistic effects when used in research protocols. 🔬 Research Applications In scientific studies, this peptide blend is utilized to: Study Growth Hormone Dynamics: Investigating the patterns and regulation of GH secretion. Metabolic Research: Understanding the role of GH in metabolism, including fat metabolism and muscle growth. Aging and Longevity Studies: Exploring the effects of GH on aging processes and potential therapeutic applications. Sleep and Recovery Research: Examining how GH influences sleep patterns and recovery processes. ⚠️ Important Considerations Research Use Only: These peptides are intended strictly for laboratory research and are not approved for human or veterinary use. Legal Status: The legality of purchasing and possessing these peptides varies by country and jurisdiction. It's essential to consult local regulations before acquiring them. Storage and Handling: Proper storage conditions are crucial to maintain peptide stability. Typically, lyophilized peptides should be stored at -20°C or colder and protected from light. Reconstitution should be done with appropriate solvents, and solutions should be stored at 4°C and used within a specified timeframe. Mod GRF 1-29 + Ipamorelin (5/5 mg) is primarily used in scientific research and clinical studies to investigate its effects on human growth hormone (GH) release and related metabolic functions. It is not FDA-approved for general medical use, but here are the commonly researched uses and potential applications: Stimulation of Growth Hormone (GH) Release Both peptides work synergistically to enhance the natural pulsatile release of GH from the pituitary gland. Mod GRF 1-29 initiates GH release, while Ipamorelin amplifies it by mimicking ghrelin. Anti-Aging Studies GH has regenerative effects on tissues, so researchers study this combo to explore its potential for: Improving skin elasticity Increasing energy levels Enhancing sleep quality Muscle Growth and Recovery (in studies) GH can help stimulate muscle protein synthesis and recovery. This combo is sometimes researched for its effects on lean muscle mass and exercise recovery. Fat Loss & Metabolic Support GH mobilizes stored fat, making this blend of interest in obesity and metabolic syndrome research. May support lipolysis (fat breakdown) in clinical models. Bone Density Studies GH supports bone mineralization. This combo is explored for potential applications in osteopenia/osteoporosis research. Sleep Improvement GH release is tied to deep sleep stages; researchers observe whether this combo improves sleep architecture and REM sleep. Modified GRF (1-29) acts to increase growth hormone production and release by binding to the growth-hormone-releasing hormone receptor (GHRHR) on cells in the anterior pituitary.