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Metabolic & Weight Management Peptides

Contact Us on telegram or WhatsApp +917887449821 +919168783773 +91 9529672584 +91 7499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://wa.me/c/917499402610 Name Semaglutide Purity ≥98% (as tested by HPLC, High-Performance Liquid Chromatography) CAS Number 910463-68-2 Molecular Formula C₁₈₇H₂₉₁N₄₅O₅₉ Molecular Weight ~4113.58 g/mol Peptide Sequence Modified GLP-1 (7-37) analog with substitutions to enhance stability Form Lyophilized powder (freeze-dried) Content 3mg per vial Semaglutide is a medication originally developed for type 2 diabetes and obesity treatment. It's a GLP-1 receptor agonist, meaning it mimics the hormone GLP-1, which helps regulate blood sugar and appetite. Type 2 Diabetes Management Lowers blood sugar by increasing insulin release and reducing glucagon secretion. Helps patients achieve better glycemic control. Weight Loss (Obesity or Overweight with Comorbidities) Reduces appetite and slows gastric emptying. FDA-approved under the brand name Wegovy for chronic weight management. 💉 Semaglutide 3mg – Dosing Guide (Research and Clinical Context) ✅ Clinically Approved Dosing (Prescription Use) Under brand names like Ozempic (for diabetes) and Wegovy (for weight loss), the FDA-approved semaglutide dosing follows this gradual titration to minimize side effects: Week Dose (Subcutaneous Injection) Weeks 1–4 0.25 mg once weekly Weeks 5–8 0.5 mg once weekly Weeks 9–12 1.0 mg once weekly (maintenance or increase as needed) Weeks 13+ 1.7 mg – 2.4 mg weekly (Wegovy max) or up to 2.0 mg (Ozempic max) Route: Subcutaneous injection (abdomen, thigh, or upper arm) Frequency: Once per week, same day/time ⚠️ Important Notes Side Effects: Can include nausea, vomiting, diarrhea, abdominal pain, and risk of pancreatitis. Not for Type 1 Diabetes or Ketoacidosis. Only certain brands and dosages are approved for specific uses.

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Diabetes & chronic weight management

ELITE TIRZEPATIDE 120mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Type 2 Diabetes Mellitus Main FDA-approved indication (as Mounjaro). Improves blood sugar control by: Increasing insulin secretion. Reducing glucagon (a sugar-raising hormone). Slowing gastric emptying. Chronic Weight Management Approved under brand name Zepbound in the U.S. Used in adults with: BMI ≥30 (obesity), or BMI ≥27 with weight-related conditions (like hypertension, high cholesterol, PCOS). Form: A multi-dose prefilled pen or vial designed for repeated subcutaneous use. This contrasts with single-dose pens (available in fixed-dose strengths like 5, 10, 15 mg) Content: Total of up to 120 mg of tirzepatide per pen/vial (commonly seen in compounded products) It's cost-effective (multiple doses in one pen). Allows customized weekly dosing (e.g. 7.5mg, 10mg, 12.5mg, 15mg). Often compounded by pharmacies for people needing dose flexibility. MULTI USE PEN ADJUSTABLE PEN BUY NOW WORLD WIDE SHIPPING AVAILABLE

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Diabetes & chronic weight management

TIZARO TIRZEPATIDE 7.5mg BUY'S IN CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ DISCRIBTION :- Type 2 Diabetes Mellitus (T2DM) Helps lower blood sugar (HbA1c) effectively Improves insulin sensitivity and secretion Reduces fasting and post-meal glucose spikes ➡️ Often used when 5 mg dose is tolerated well but greater glycemic control is needed. Weight Loss / Obesity Treatment Used for chronic weight management in: Adults with BMI ≥30, or BMI ≥27 with obesity-related conditions (diabetes, hypertension, etc.) At 7.5 mg, patients often report: Stronger appetite suppression Increased fat loss Accelerated body weight reduction vs lower doses ❤️ Cardiometabolic Benefits (Research-based) Helps reduce: LDL cholesterol and triglycerides Blood pressure Systemic inflammation (CRP) 7.5 mg Once weekly (SC injection) Injection sites Abdomen, thigh, upper arm Titration path 2.5 mg → 5 mg → 7.5 mg Max approved dose Up to 15 mg (in some proto How Tizaro Works (Mechanism) GLP-1 action: Enhances insulin release, slows gastric emptying, reduces appetite GIP action: Increases fat metabolism, improves insulin response Together, this dual pathway provides: Superior glucose control Greater weight loss vs other GLP-1 drugs (like semaglutide) BUY FROM US WORLD WIDE SHIPPING WITH GOOD PACKAGING CONTACT US FOR BEST OFFERS & DEALS

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Metabolic & Weight Management Peptides

TO BUY Tirzepatide (40mg) Contact Us on telegram or WhatsApp +917887449821 +919168783773 +91 9529672584 +91 7499402610 Mail :- skyblueinternational033@gmail.com Internationalskyblue@gmail.com Viwe our catalog :- https://wa.me/c/917499402610 Tirzepatide is a dual agonist for the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors. The drug leads to significantly improved glycemic control and weight reduction in patients with T2DM, maximizing benefits similar to GLP-1 medications such as semaglutide. Tirzepatide (Zepbound brand) is used for weight loss, to help lose weight and keep weight off. Tirzepatide works for weight loss by decreasing appetite and slowing the movement of food from the stomach into the small intestine, which may make you feel full more quickly and for a longer period. The Zepbound brand of tirzepatide is also used for moderate to severe obstructive sleep apnea (OSA) in adults with obesity. Tirzepatide is a once-weekly injection given under the skin using a pen (autoinjector). Zepbound (tirzepatide) is FDA-approved for weight loss in adults with obesity or who are overweight and have weight-related medical problems or OSA. Zepbound helps you to lose weight and maintain weight loss and should be combined with diet and exercise. Tirzepatide (Mounjaro brand) is used for type 2 diabetes to help improve blood sugar levels. In type 2 diabetes, tirzepatide decreases blood sugar levels by helping release insulin when blood sugar levels are high, lowering the amount of sugar the liver makes, and slowing food movement through the intestines. Mounjaro should be used together with diet and exercise. Mounjaro (tirzepatide) is FDA-approved to treat adults with type 2 diabetes and should be used together with diet and exercise. It can be used as a single therapy (on its own) or with other diabetes medicines, including sulfonylureas, SGLT2 inhibitors, or metformin. It is not known if tirzepatide can be used in people who have had pancreatitis. Tirzepatide should not be used in people who have type 1 diabetes. Normally, when we eat, natural hormones called GIP and GLP-1 are released by the gut. These hormones increase insulin release, suppress appetite, slow gastric emptying, and increase the feeling of fullness. Tirzepatide works like our natural hormones GIP and GLP-1 by activating the GIP and GLP-1 receptors. Tirzepatide is a GIP and GLP-1 receptor agonist. Tirzepatide works (mechanism of action) by activating both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors. Weight Loss Achieved: tirzepatide: 64.6% of participants lost 15% of their weight semaglutide: 40.1% of participants lost 15% of their weighT Tirzepatide (40mg) USE FOR WEIGHT LOSS Mechanisms: Increases insulin release in response to glucose Reduces glucagon secretion Slows digestion to avoid sugar spikes

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Metabolic & Weight Management Peptides

Retatrutide 16mg is being developed to target multiple metabolic conditions, with its primary uses in obesity management, type 2 diabetes, and fatty liver disease. Retatrutide is an investigational triple hormone receptor agonist (GLP-1, GIP, and glucagon receptors) Main Uses of Retatrutide 1. Obesity Treatment Primary target: Adults with obesity (BMI ≥30) or overweight (BMI ≥27) with a weight-related condition. Effectiveness: Up to 24.2% body weight loss at the highest tested dose (12 mg) over 48 weeks. Outperformed semaglutide (Wegovy) and tirzepatide (Zepbound) in trials. Mechanism: Appetite suppression Slowed gastric emptying Increased energy expenditure Type 2 Diabetes Management Improves blood glucose control by: Enhancing insulin sensitivity Increasing insulin secretion Reducing glucagon levels (in a glucose-dependent way) Massive reductions in liver fat (up to 82.4% in some patients) Helps improve: Liver enzyme profiles (ALT, AST) Hepatic insulin resistance SKYBLUE INTERNATIONAL is a trusted global pharmaceutical export company specializing in the export of high-quality medicines. With a strong commitment to healthcare excellence, we supply a wide range of branded and generic medicines to countries including the USA, UK, Australia, UAE, Canada, Singapore, and the Philippines. Our focus is on reliability, compliance, and timely delivery to meet the global demand for affordable and effective medical solutions. Medicine 💊 Retatrutide (16mg) BUY FROM SKYBLUE INTERNATIONAL Weight reduction Improved insulin sensitivity Hormonal balancing

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Growth Hormone Secretagogues

CJC-1295 DAC (5mg) FAST DELIVERY TO AUSTRALIA SKYBLUE INTERNATIONAL is a trusted global pharmaceutical export company specializing in the export of high-quality medicines. With a strong commitment to healthcare excellence, we supply a wide range of branded and generic medicines to countries including the USA, UK, Australia, UAE, Canada, Singapore, and the Philippines. Our focus is on reliability, compliance, and timely delivery to meet the global demand for affordable and effective medical solutions. Medicine 💊 USES : CJC-1295 DAC (Drug Affinity Complex) is a long-acting growth hormone-releasing hormone (GHRH) analog designed to elevate IGF-1 and growth hormone (GH) levels for days after a single injection. Below is a detailed breakdown of its primary applications, mechanisms, and protocols. Fat Loss & Metabolism Boosts lipolysis (fat breakdown), especially stubborn visceral fat. Improves insulin sensitivity → Supports metabolic health. Mechanism: Binds to GHRH receptors in the pituitary → sustained GH release (elevates IGF-1 for 5-7 days per dose). Half-life: 6-8 days (due to DAC modification, which prevents rapid breakdown). Key Difference vs. CJC-1295 (no DAC): CJC-1295 DAC → Long-lasting effects (fewer injections needed). Standard CJC-1295 → Shorter duration (requires daily dosing). Standard Protocol (5mg Vial) Reconstitution: Mix with 2mL bacteriostatic water (yields 2.5mg/mL). Dosing: Beginner: 1mg (0.4mL) 2x/week (e.g., Monday & Thursday). Advanced: 2mg (0.8mL) 2x/week (for maximum IGF-1 elevation). Cycle Length: 8-12 weeks (followed by a 4-week break). ✅ Best for: Athletes wanting sustained muscle growth & recovery. Men/women targeting fat loss + anti-aging benefits. Those who prefer fewer injections (vs. daily peptides). WE EXPORT IN UK WE EXPORT IN SINGAPORE WE EXPORT IN DUBAI WE EXPORT IN JAPAN WE EXPORT IN CANADA

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Growth Hormone Secretagogues

CJC-1295 + Ipamorelin (5/5mg) PEPTIDE SCIENCE IS AVAILABLE IN INDIA CJC-1295 DAC, also known as DAC:GRF (short for drug affinity complex:growth hormone-releasing factor), is a synthetic analogue of growth hormone-releasing hormone (GHRH) (also known as growth hormone-releasing factor (GRF)) and a growth hormone secretagogue (GHS) which was developed by ConjuChem Biotechnologies.[1][2][3] It is a modified form of GHRH (1-29) with improved pharmacokinetics, especially in regard to half-life. 1. Primary Uses ✅ Muscle Growth & Performance Enhancement Boosts lean muscle mass by increasing protein synthesis. Speeds up recovery from workouts or injuries (tendons, ligaments). Popular among athletes, bodybuilders, and fitness enthusiasts. ✅ Fat Loss & Metabolism Enhances lipolysis (fat breakdown), especially stubborn belly fat. Improves insulin sensitivity (beneficial for metabolic health). Anti-Aging & Longevity Stimulates collagen production → Firmer skin, reduced wrinkles. Supports joint health → Reduces age-related stiffness/pain. May improve sleep quality & cognitive function (GH regulates brain health). ✅ Injury & Tissue Repair Accelerates healing of muscles, tendons, and cartilage. Used by athletes recovering from strains or surgeries. SKYBLUE INTERNATIONAL is a trusted global pharmaceutical export company specializing in the export of high-quality medicines. With a strong commitment to healthcare excellence, we supply a wide range of branded and generic medicines to countries including the USA, UK, Australia, UAE, Canada, Singapore, and the Philippines. Our focus is on reliability, compliance, and timely delivery to meet the global demand for affordable and effective medical solutions. Medicine WE EXPORT TO SINGAPORE WE EXPORT TO AUD WE EXPORT TO CAD WE EXPORT TO UK WE EXPORT TO UAE

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Growth Hormone Secretagogues

The first 29 amino acids of GHRH were discovered to be as equally potent as its full 44 amino acid structure[1][2] This fragment became known as GRF (1-29). However, due to a rapid metabolic clearance analogues of GRF (1-29) were synthesized to enhance the biological activity and reduce the rapidity of metabolic clearance. These analogues were primarily created by substituting amino acids within the peptide structure for amino acids more resistant to enzymatic cleavage. One early analogue substituted the amino acid L-alanine (abbreviated as Ala or A) at the 2nd position of the peptide structure for its optical isomer (mirror image), D-alanine (abbreviated as D-Ala). This substitution resulted in a peptide bond between D-Ala and the 3rd amino acid in the structure aspartic acid (Asp) more able to resist rapid cleavage by the enzyme dipeptidyl peptidase-4, a cleavage which had previously led to an inactive peptide fragment.[3][4] This successful modification prompted the further creation of analogues with additional amino acid substitutions. Ipamorelin: A selective growth hormone secretagogue, Ipamorelin stimulates the release of GH by mimicking ghrelin's action on the ghrelin receptor. It is known for its specificity and minimal side effects compared to other GH-releasing peptides. Mod GRF 1-29 (CJC-1295 without DAC): This is a modified version of the first 29 amino acids of growth hormone-releasing hormone (GHRH). The modifications extend its half-life and enhance its ability to stimulate the pituitary gland to release GH. It is often used in research to study GH secretion patterns and related metabolic effects. ⚖️ Dosage and Composition The 5/5 mg blend indicates that each vial contains 5 mg of Mod GRF 1-29 and 5 mg of Ipamorelin, totaling 10 mg per vial. This combination is designed to provide a balanced stimulation of GH release, potentially offering synergistic effects when used in research protocols. 🔬 Research Applications In scientific studies, this peptide blend is utilized to: Study Growth Hormone Dynamics: Investigating the patterns and regulation of GH secretion. Metabolic Research: Understanding the role of GH in metabolism, including fat metabolism and muscle growth. Aging and Longevity Studies: Exploring the effects of GH on aging processes and potential therapeutic applications. Sleep and Recovery Research: Examining how GH influences sleep patterns and recovery processes. ⚠️ Important Considerations Research Use Only: These peptides are intended strictly for laboratory research and are not approved for human or veterinary use. Legal Status: The legality of purchasing and possessing these peptides varies by country and jurisdiction. It's essential to consult local regulations before acquiring them. Storage and Handling: Proper storage conditions are crucial to maintain peptide stability. Typically, lyophilized peptides should be stored at -20°C or colder and protected from light. Reconstitution should be done with appropriate solvents, and solutions should be stored at 4°C and used within a specified timeframe. Mod GRF 1-29 + Ipamorelin (5/5 mg) is primarily used in scientific research and clinical studies to investigate its effects on human growth hormone (GH) release and related metabolic functions. It is not FDA-approved for general medical use, but here are the commonly researched uses and potential applications: Stimulation of Growth Hormone (GH) Release Both peptides work synergistically to enhance the natural pulsatile release of GH from the pituitary gland. Mod GRF 1-29 initiates GH release, while Ipamorelin amplifies it by mimicking ghrelin. Anti-Aging Studies GH has regenerative effects on tissues, so researchers study this combo to explore its potential for: Improving skin elasticity Increasing energy levels Enhancing sleep quality Muscle Growth and Recovery (in studies) GH can help stimulate muscle protein synthesis and recovery. This combo is sometimes researched for its effects on lean muscle mass and exercise recovery. Fat Loss & Metabolic Support GH mobilizes stored fat, making this blend of interest in obesity and metabolic syndrome research. May support lipolysis (fat breakdown) in clinical models. Bone Density Studies GH supports bone mineralization. This combo is explored for potential applications in osteopenia/osteoporosis research. Sleep Improvement GH release is tied to deep sleep stages; researchers observe whether this combo improves sleep architecture and REM sleep. Modified GRF (1-29) acts to increase growth hormone production and release by binding to the growth-hormone-releasing hormone receptor (GHRHR) on cells in the anterior pituitary.

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Growth Hormone Secretagogues

Tesamorelin + CJC-1295 + Ipamorelin (6/3/3mg) FAST DELIVERY TO DOORSTEPS CJC-1295 is an incredibly effective peptide which works by stimulating the release of your own body's growth hormones (which drop quickly after the age of 30). Research has shown that CJC-1295 can increase growth hormone levels by 200-1000% and the elevated growth hormone production continued for up to 6 days. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Powder for Solution. Conclusion: Treatment with tesamorelin was generally well tolerated and resulted in sustained decreases in VAT and triglycerides over 52 weeks without aggravating glucose. Though effects on VAT are sustained during treatment for 52 weeks, these effects do not last beyond the duration of treatment. Signs of high blood sugar like confusion, feeling sleepy, unusual thirst or hunger, passing urine more often, flushing, fast breathing, or breath that smells like fruit. A fast heartbeat. Dizziness or passing out. Flushing. 1. Primary Medical & Performance Uses A. Fat Loss (Especially Visceral Fat) ✅ Tesamorelin (6mg): FDA-approved for HIV lipodystrophy (reduces abdominal fat). Targets stubborn belly fat even in non-HIV patients. ✅ CJC-1295 (3mg) + Ipamorelin (3mg): Amplifies growth hormone (GH) pulses for enhanced fat metabolism. Preserves muscle during calorie deficits. B. Muscle Growth & Recovery Boosts IGF-1 levels → Increases protein synthesis. Accelerates repair of tendons/ligaments (ideal for athletes). C. Anti-Aging & Longevity Improves skin elasticity (collagen stimulation). Enhances sleep quality (GH promotes deep sleep cycles). May support cognitive function (neuroprotective effects). D. Metabolic Health Improves insulin sensitivity (beneficial for prediabetes/metabolic syndrome). Lowers triglycerides (cardiovascular support). 2. Mechanism of Action Peptide Target Effect Tesamorelin GHRH Receptor (Pituitary) Stimulates GH release, specifically reduces visceral fat. CJC-1295 GHRH Receptor (Pituitary) Long-acting GH release (elevates IGF-1 for days). Ipamorelin Ghrelin Receptor Selective GH boost (no cortisol/prolactin spikes). Synergy: Tesamorelin targets fat stores, while CJC-1295 + Ipamorelin prolong GH benefits for muscle and recovery. 3. Dosage & Administration Standard Protocol Blend Ratio: 6mg Tesamorelin + 3mg CJC-1295 + 3mg Ipamorelin per vial. Daily Dose: Tesamorelin: 1–2mg/day (e.g., 1mg AM, 1mg PM). CJC-1295 + Ipamorelin: 100–300mcg each, 1–2x/day (post-workout or bedtime). Cycle Length: 8–12 weeks (followed by 4-week break). Reconstitution Mix with 2–3mL bacteriostatic water (for precise dosing). Storage: Refrigerate after reconstitution (stable for 4–6 weeks). 4. Expected Results & Timeline 📌 Weeks 1–4: Reduced bloating, improved sleep, increased energy. 📌 Weeks 4–8: Visible fat loss (especially abdomen), faster workout recovery. 📌 Weeks 8–12: Lean muscle definition, tighter skin, enhanced endurance. (Optimal with strength training + low-sugar diet.) Final Verdict ✅ Best for: Men/women targeting stubborn belly fat. Athletes wanting muscle preservation + recovery. Anti-aging (skin, cognition, longevity). Description Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Description Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Tesamorelin may sometimes be given at home to patients who do not need to be in a hospital or clinic. If you are using this medicine at home, your doctor or nurse will teach you how to prepare and inject the medicine. Be sure that you understand how to use the medicine. Tesamorelin injection comes with a patient information leaflet and patient instructions. Read the instructions and make sure you understand: How to prepare the injection. Proper use of disposable syringes. How to give the injection. How long the injection is stable. WE EXPORTY TO USA WE EXPORT TO UK WE EXPORT LO CANADA WE EXORT TO AUSTRALIA WE EXPORT ITALY WE EXPORT TO SINGAPORE

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