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'delayed puberty investigated'

Items tagged with 'delayed puberty investigated'

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Sexual & Reproductive Health Peptides

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Generic Name :- Kisspeptin-10 Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins 1. Stimulation of Gonadotropin-Releasing Hormone (GnRH) Kisspeptin-10 stimulates the hypothalamus to release GnRH, which then promotes the secretion of: Luteinizing hormone (LH) Follicle-stimulating hormone (FSH) This cascade is crucial for puberty onset, ovulation, and fertility regulation. 2. Fertility Research Used in assisted reproductive technologies (ART) and IVF studies to promote natural hormonal responses. Can potentially reduce the need for synthetic hormones like hCG. 3. Hypogonadism and Delayed Puberty Investigated as a treatment for hypogonadotropic hypogonadism (low LH/FSH due to low GnRH). May help restore reproductive function in affected individuals. 4. Polycystic Ovary Syndrome (PCOS) Studied for its role in correcting LH/FSH imbalances in PCOS patients. 5. Diagnostic Use Used to test pituitary function or the integrity of the hypothalamic-pituitary-gonadal (HPG) axis. BUY Kisspeptin-10 5mg IN CHEAP PRICE GET BEST OFFERS ON Kisspeptin-10 5mg FROM US SKYBLUE INTERNATIONAL

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Sexual & Reproductive Health Peptides

Gonadorelin 10mg , Peptide USA FAST DELIVERY Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ 1. 🎯 Diagnostic Testing of the HPG Axis Used to assess pituitary function by measuring LH/FSH response—helpful in diagnosing hypogonadism or pituitary disorders . 2. 👩‍🔬 Female Infertility & Ovulation Induction Triggers ovulation in women with irregular periods Widely used in IVF and ART, often combined with hCG, to improve ovarian response and implantation rates 3. 👨 Male Hypogonadism & Delayed Puberty Stimulates testosterone and spermatogenesis in male hypogonadotropic hypogonadism and delayed puberty Helps prevent testicular atrophy during TRT and promotes natural LH/FSH production 4. 🧬 Hormone-Sensitive Cancers (Experimental) Explored in breast and prostate cancer to suppress estrogen/testosterone over long-term use . 5. 🦴 Bone, Muscle & Metabolic Health (Research) Preliminary studies show benefits for bone density, muscle strength, mood, and metabolic function via hormone regulation . 6. 🧠 Neurological & Cognitive Research Emerging research on GnRH analogues for potential applications in Alzheimer's disease and cognitive health Diagnosing HPG axis function Boosting fertility and managing reproductive disorders Treating male hormonal deficiencies and puberty delay Evaluating emerging roles in cancer, veterinary fertility, bone/muscle health, and neurology FAST DELIVERY FOR USA FAST DELIVERY FOR UK FAST DELIVERY FOR CANADA FAST DELIVERY FOR AUSTRALIA FAST DELIVERY FOR ABU DHABI FAST DELIVERY FOR SINGAPORE

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Pharmaceutical Tablets

LUPI HCG 2000 IU INJ Hcg 2000IU Injection is used in the treatment of infertility in women. It is also helpful in the treatment of male hypogonadism (delayed puberty, and low sperm count). It works by releasing the eggs from the ovary in women and by increasing the testosterone level in men. Hcg 2000IU Injection is given as an injection under the supervision of a doctor. Your doctor will decide the right time to take the injection, so always follow your doctor's advice. The dose and how often you take it depends on what you are taking it for. You should take this medicine for as long as it is prescribed for you. The most common side effects of this medicine include injection site pain, headache, fatigue, and depression. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Male might notice acne, or sweating and deepening of the voice. If you experience dizziness, faint, abdominal pain, and vomiting after getting the injection, inform your doctor immediately. Before taking this medicine, tell your doctor if you have ever had heart disease, or had an ovarian cyst, or had thyroid gland disorder. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. You should avoid alcohol or have to follow doctor advice related to diet while taking this medicine.

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Erectile Dysfunction Medicines

Sildenafil & Dapoxetine Cenforce - LD BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, UK, EUROPE, UAE & GET 20% OFF ON BULK ORDER Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ Active Ingredients Sildenafil 50 mg + Dapoxetine 30 mg Treats Erectile dysfunction + premature ejaculation Start Time 30–60 minutes Duration Approximately 4–6 hours Erectile Dysfunction (ED) Sildenafil enhances blood flow to the penis, helping to achieve and maintain an erection during sexual excitement . Premature Ejaculation (PE) Dapoxetine increases serotonin availability, helping delay ejaculation and improve ejaculatory control. Cenforce LD is a potent combination therapy offering both improved erections and delayed ejaculation in one convenient tablet. Ideal for men experiencing both ED and PE, it helps enhance sexual performance and confidence. Sildenafil: This component of Cenforce-LD is a PDE5 inhibitor. It works by increasing blood flow to the penis, which helps men with ED to achieve an erection when they are sexually stimulated.

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Erectile Dysfunction Medicines

Sildenafil Depoxetine Cenforce D BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, UK, EUROPE, UAE & GET 20% OFF ON BULK ORDER Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ Cenforce D 160 mg is a combination drug containing 100mg of Sildenafil citrate and 60mg of Dapoxetine hydrochloride, used in the treatment of erectile dysfunction and premature ejaculation in men 18 to 64 years of age. It helps men get and maintain erection and improve ejaculation time. Cenforce D is a combination tablet containing: Sildenafil citrate 100 mg (a PDE‑5 inhibitor) Dapoxetine hydrochloride 60 mg (a quick-acting SSRI) Cenforce D treats two common male sexual dysfunctions simultaneously : Erectile Dysfunction (ED) Sildenafil eases blood flow to the penis, aiding erection when sexually stimulated Premature Ejaculation (PE) Dapoxetine increases serotonin action, delaying ejaculation and improving control. Cenforce D offers a comprehensive, dual-action treatment for men facing both ED and PE. It provides improved erections and delayed ejaculation in a single dose, lasting several hours. However, because of potential serious side effects and interactions, it should only be used under strict medical supervision—especially if you have underlying health conditions or are on other medications.

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Miscellaneous Peptides

Bronchogen 20mg, Peptide BUY IN CANADA, SINGAPORE, AUSTRALIA Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪+919529672584‬ ‪ +917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Peptide-Based Lung Support Acts as a bioregulator, targeting lung tissue at the cellular level—enhancing DNA stability, reducing inflammation, and promoting epithelial repair and surfactant production in preclinical studies Investigated for potential in chronic respiratory conditions like COPD, asthma, and bronchitis—reducing mucus, bronchospasm, and coughing Anti-Inflammatory & Anti-Aging May stabilize DNA, reduce inflammatory cytokines, and support healthy lung function—promising for age-related lung decline Immunomodulation Proposed to support immune function in the lungs, reducing exacerbations in smokers and older individuals Bronchogen 20 mg is a promising experimental peptide aimed at improving lung structure and function. While early data—both preclinical and anecdotal—suggest benefits for inflammation and airflow, it remains unapproved and under-researched. If you're exploring respiratory support, consult a medical professional and consider established therapies (e.g., bronchodilators, inhaled steroids). WORLD WIDE SHIPPING SHIPPING TO YOUR DOOR STEPS

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NAD+ & Mitochondrial Support Peptides

Contact Us on telegram or WhatsApp +917887449821‬ +919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ MOTS-c (5mg) :- MOTS-c (5mg), a mitochondrial-derived peptide, is being investigated for its potential to treat metabolic disorders, improve muscle function, and promote healthy aging. It's believed to play a role in regulating energy metabolism, insulin resistance, and the inflammatory response. While research is ongoing, MOTS-c is being explored as a potential therapeutic strategy for conditions like obesity, age-related diseases, and even osteoporosis. MOTS-c stands for 'Mitochondrial Open Reading Frame of the 12S rRNA-c'. It is a 16-amino acid peptide that acts like a hormone, influencing metabolism, stress response, and cellular energy production. Unlike other peptides, it originates from mitochondrial DNA, not nuclear DNA. Exercise and Aging: MOTS-c can enhance exercise endurance and potentially counteract age-related muscle decline Bone Health: Osteoporosis: MOTS-c has been shown to inhibit osteoclast activity and reduce bone loss, suggesting a potential role in preventing and treating osteoporosis. Other Potential Benefits: Anti-inflammatory Effects: MOTS-c may help regulate the inflammatory response, which is implicated in various diseases. Brain Health: Research indicates MOTS-c may improve cognitive function and memory. Cardiovascular Health: MOTS-c has been linked to improved heart function and blood vessel health. 🧠 1. Anti-Aging & Longevity Increases mitochondrial efficiency. Activates AMPK (AMP-activated protein kinase), a key longevity pathway. Promotes cellular stress resistance (e.g., oxidative and metabolic stress). ⚡ 2. Metabolic Health Improves insulin sensitivity and glucose metabolism. Supports weight loss and fat oxidation. Reduces markers of metabolic syndrome and type 2 diabetes in animal models. 💪 3. Exercise & Performance Enhancement Enhances endurance and physical capacity. Protects muscles from exercise-induced stress. Mimics some effects of exercise even without activity ('exercise mimetic'). 🧬 4. Mitochondrial Health Promotes mitochondrial biogenesis. Helps maintain mitochondrial DNA integrity and function under stress. 🧠 5. Neuroprotection (early-stage research) May protect brain cells from oxidative and metabolic damage. MOTS-c (5mg) fast delivery in london

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NAD+ & Mitochondrial Support Peptides

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+91 9529672584‬ ‪+91 7499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ SS-31 (25mg) :- SS-31, also known as elamipretide or Bendavia, is a mitochondria-targeting peptide that has shown potential in treating various conditions by improving mitochondrial function. It has been investigated for its antioxidant, anti-inflammatory, and anti-apoptotic properties, particularly in the context of neurodegenerative diseases, inflammatory diseases, and ischemia-reperfusion injury. SS-31 (also known as Elamipretide) is a synthetic peptide that targets and protects mitochondria, the energy-producing structures in cells. The 25 mg dose is commonly used in clinical trials and experimental protocols. Use Details 🫀 Heart Disease Improves heart function in heart failure and ischemic heart disease 🧠 Neurodegenerative Diseases May protect brain cells in conditions like Alzheimer’s, Parkinson’s 👁️ Eye Disorders Studied in dry age-related macular degeneration (dry AMD) 💪 Muscle Fatigue Helps with exercise intolerance and mitochondrial myopathy 🧬 Mitochondrial Dysfunction Repairs damaged mitochondria, boosts ATP production 🧫 Kidney Protection May reduce kidney injury in acute or chronic kidney disease 🧓 Age-Related Fatigue Improves mobility and stamina in older adults How It Works Targets mitochondria directly Binds to cardiolipin in the mitochondrial membrane Prevents oxidative damage Restores energy production (ATP) 💉 Common Dosage Form 25 mg usually administered subcutaneously (under the skin) once daily in studies. SS-31, also known as Elamipretide, is a synthetic peptide designed to improve mitochondrial function and reduce oxidative stress. It's primarily used to protect and restore mitochondrial function, specifically by reducing oxidative stress, stabilizing cardiolipin (a mitochondrial phospholipid), and improving mitochondrial energy production. Research suggests it may also be beneficial in conditions like Alzheimer's, brain injury, and kidney disease. The 25mg dosage refers to the amount of SS-31 in a single dose, often administered via injection. Mitochondrial Target: SS-31 specifically targets mitochondria, the powerhouses of cells, and is thought to protect and restore their function.

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