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Erectile Dysfunction Medicines

TADALAFIL, VIDALISTA 2.5mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, UK, EUROPE, UAE & GET 20% OFF ON BULK ORDER Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ BENIFITS :- Tadalafil is used to treat men who have erectile dysfunction (also called sexual impotence). Tadalafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. Daily low-dose therapy: Helps men achieve and sustain erections with sexual stimulation over time. Approved for everyday use at 2.5 mg—offered for spontaneous sexual activity without planning. Onset occurs within 30 minutes, and effects can last up to 36 hours, though you won't be erect continuously. Dosage & Administration:- When to take: Usually once daily, at the same time each day—often with or without food. Recommended dose: 2.5 mg once daily; may be increased to 5 mg daily based on response and tolerability. Avoid multiple doses: Taking more than one dose daily increases risk without added benefit. Erectile Dysfunction 2.5 mg daily Maintains readiness; onset within 30 min, up to 36 hrs Benign Prostatic Hyperplasia 2.5 mg–5 mg daily Relieves urinary symptoms Pulmonary Hypertension N/A (higher dose) Off‑label; requires specialized guidance

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Erectile Dysfunction Medicines

Sildenafil Citrate CENFORCE 25mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, UK, EUROPE, UAE & GET 10% OFF ON BULK ORDER Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ When used: For men with occasional, moderate, or persistent erectile dysfunction, especially if lower doses (100 mg or less) weren't effective . Mechanism: It's a PDE‑5 inhibitor that increases cGMP to relax blood vessels and improve blood flow into the penis—helping to achieve and maintain an erection with sexual stimulation Sildenafil (the same medication) is also FDA-approved for PAH; Cenforce, like other sildenafil generics, is sometimes used off-label for this condition. Dosage & Administration Take one tablet (120 mg) about 30–60 minutes before planned sexual activity. Take one tablet (120 mg) about 30–60 minutes before planned sexual activity. Swallow whole with water; taking it on an empty stomach can speed up effects—heavy/fatty meals may delay onset. BUY NOW TO GET BEST OFFERS & DEALS

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Sexual & Reproductive Health Peptide

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Generic Name Bremelanotide 1. Hypoactive Sexual Desire Disorder (HSDD) in Women FDA-approved in 2019 under the brand Vyleesi for pre-menopausal women with generalized HSDD unrelated to other medical or psychological condition Improves sexual desire, arousal, and reduces distress linked to low libido 2. Erectile Dysfunction (ED) in Men (Off‑Label) PT‑141 initiates erections via central nervous system pathways, increasing sexual desire and erection quality—even in men unresponsive to PDE‑5 inhibitors Demonstrated increased duration and rigidity of erections in trials 3. Sexual Arousal Support Boosts libido in both genders, addresses low sexual drive and arousal disorders, potentially enhancing orgasm quality and reducing refractory time Bremelanotide is a 7 amino acid peptide used to treat hypoactive sexual desire disorder in premenopausal women. Bremelanotide does not interact with alcohol. The mechanism by which bremelanotide's action on receptors translates to a clinical effect is still unknown. Bremelanotide was first described in the literature in 2003 when it was known by the investigational code PT-141.1 Since then it was investigated for its place in treating sexual dysfunction in men and women but is now only indicated for women.1,2,5 Other drugs used to treat female sexual dysfunction include flibanserin, estrogen, ospemifene, and prasterone. Bremelanotide was granted FDA approval Bremelanotide is an agonist of many melanocortin receptors which in order of potency are MC1R, MC4R, MC3R, MC5R, and MC2R.5 The mechanism by which agonism of these receptors translates to an improvement in hypoactive sexual desire disorder is currently unknown, however MC4R receptors are present in many areas of the central nervous system. MC3R and MC4R are found in the hypothalamus and are involved in food intake and energy homeostasis. Bremelanotide is a 7 amino acid and so its metabolism consists of multiple hydrolysis reactions.

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Metabolic & Weight Management Peptides

Contact Us on telegram or WhatsApp +917887449821 +919168783773 +91 9529672584 +91 7499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://wa.me/c/917499402610 Name Semaglutide Purity ≥98% (as tested by HPLC, High-Performance Liquid Chromatography) CAS Number 910463-68-2 Molecular Formula C₁₈₇H₂₉₁N₄₅O₅₉ Molecular Weight ~4113.58 g/mol Peptide Sequence Modified GLP-1 (7-37) analog with substitutions to enhance stability Form Lyophilized powder (freeze-dried) Content 3mg per vial Semaglutide is a medication originally developed for type 2 diabetes and obesity treatment. It's a GLP-1 receptor agonist, meaning it mimics the hormone GLP-1, which helps regulate blood sugar and appetite. Type 2 Diabetes Management Lowers blood sugar by increasing insulin release and reducing glucagon secretion. Helps patients achieve better glycemic control. Weight Loss (Obesity or Overweight with Comorbidities) Reduces appetite and slows gastric emptying. FDA-approved under the brand name Wegovy for chronic weight management. 💉 Semaglutide 3mg – Dosing Guide (Research and Clinical Context) ✅ Clinically Approved Dosing (Prescription Use) Under brand names like Ozempic (for diabetes) and Wegovy (for weight loss), the FDA-approved semaglutide dosing follows this gradual titration to minimize side effects: Week Dose (Subcutaneous Injection) Weeks 1–4 0.25 mg once weekly Weeks 5–8 0.5 mg once weekly Weeks 9–12 1.0 mg once weekly (maintenance or increase as needed) Weeks 13+ 1.7 mg – 2.4 mg weekly (Wegovy max) or up to 2.0 mg (Ozempic max) Route: Subcutaneous injection (abdomen, thigh, or upper arm) Frequency: Once per week, same day/time ⚠️ Important Notes Side Effects: Can include nausea, vomiting, diarrhea, abdominal pain, and risk of pancreatitis. Not for Type 1 Diabetes or Ketoacidosis. Only certain brands and dosages are approved for specific uses.

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Metabolic & Weight Management Peptides

Semaglutide 3mg USES Brand Name: Rybelsus Formulation: Oral tablet Dosing: Once daily, taken on an empty stomach with water Type 2 Diabetes Management (Primary Use) Initial dose: 3 mg is used as a starting dose to allow the body to adjust to the medication. It is not therapeutic on its own—patients are usually titrated to 7 mg or 14 mg for full glucose-lowering effect. Helps lower blood sugar (HbA1c) in adults with Type 2 diabetes. How It Works. Semaglutide is a GLP-1 receptor agonist, which: Stimulates insulin secretion (when glucose is high) Reduces glucagon secretion Slows gastric emptying Reduces appetite (mildly at this dose) DOSAGE :- Start at 0.25 mg once weekly. After 4 weeks, increase the dose to 0.5 mg once weekly. If after at least 4 weeks additional glycemic control is needed, increase to 1 mg once weekly (2.1).  Administer once weekly at any time of day, with or without meals  If a dose is missed administer within 5 days of missed dose  Inject subcutaneously in the abdomen, thigh, or upper arm Indications & Uses Initial dose for Type 2 diabetes mellitus treatment (used for 30 days before titration to 7 mg or 14 mg) Helps lower blood glucose (HbA1c) Used in combination with diet and exercise Wegovy (semaglutide) for weight loss Wegovy (semaglutide) is used for weight loss and weight maintenance in patients 12 years and older with obesity Used for reducing major cardiovascular event risks (such as heart attack, stroke, or death) in adults with type 2 diabetes with known heart disease Injection is given 1 time a week under the skin of the stomach (belly), the thigh, or the upper arm, using an autoinjector (pen) This injection should be used in addition to a reduced-calorie diet and increased physical activity

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Metabolic & Weight Management Peptides

Retatrutide (10mg) USA FAST DELIVERY Retatrutide (10mg : - Obesity and Overweight Management Retatrutide has demonstrated significant efficacy in promoting weight loss. In clinical trials, participants have achieved up to 24.2% weight loss over 48 weeks, outperforming existing treatments like semaglutide and tirzepatide. Form: Subcutaneous injection (once weekly) Dose Titration: To reduce side effects (especially GI issues), dosing typically starts low and increases over time. What Is Retatrutide Used For? Retatrutide is being developed to target multiple metabolic conditions, with its primary uses in obesity management, type 2 diabetes, and fatty liver disease. Retatrutide activates the GIP, GLP-1 and glucagon receptors that are involved with controlling hunger and satiety, allowing people to feel fuller after eating for longer. This helps to regulate blood sugar levels, leading to weight loss. Non-Alcoholic Fatty Liver Disease (NAFLD) Retatrutide has led to significant reductions in liver fat in patients with metabolic dysfunction-associated steatotic liver disease (MASLD), with reductions up to 82.4% observed in clinical trials. Target Population Adults with obesity (BMI ≥30) or overweight (BMI ≥27) with comorbidities (e.g., type 2 diabetes, hypertension) Adults with type 2 diabetes, especially those who need better weight and glucose control EXPORT FROM INDIA IN CHEAPEST PRICE. Retatrutide is an investigational drug still in clinical trials and has not yet been approved by the FDA for general use. However, based on Phase 2 clinical trials.

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Growth Hormone Secretagogues

The first 29 amino acids of GHRH were discovered to be as equally potent as its full 44 amino acid structure[1][2] This fragment became known as GRF (1-29). However, due to a rapid metabolic clearance analogues of GRF (1-29) were synthesized to enhance the biological activity and reduce the rapidity of metabolic clearance. These analogues were primarily created by substituting amino acids within the peptide structure for amino acids more resistant to enzymatic cleavage. One early analogue substituted the amino acid L-alanine (abbreviated as Ala or A) at the 2nd position of the peptide structure for its optical isomer (mirror image), D-alanine (abbreviated as D-Ala). This substitution resulted in a peptide bond between D-Ala and the 3rd amino acid in the structure aspartic acid (Asp) more able to resist rapid cleavage by the enzyme dipeptidyl peptidase-4, a cleavage which had previously led to an inactive peptide fragment.[3][4] This successful modification prompted the further creation of analogues with additional amino acid substitutions. Ipamorelin: A selective growth hormone secretagogue, Ipamorelin stimulates the release of GH by mimicking ghrelin's action on the ghrelin receptor. It is known for its specificity and minimal side effects compared to other GH-releasing peptides. Mod GRF 1-29 (CJC-1295 without DAC): This is a modified version of the first 29 amino acids of growth hormone-releasing hormone (GHRH). The modifications extend its half-life and enhance its ability to stimulate the pituitary gland to release GH. It is often used in research to study GH secretion patterns and related metabolic effects. ⚖️ Dosage and Composition The 5/5 mg blend indicates that each vial contains 5 mg of Mod GRF 1-29 and 5 mg of Ipamorelin, totaling 10 mg per vial. This combination is designed to provide a balanced stimulation of GH release, potentially offering synergistic effects when used in research protocols. 🔬 Research Applications In scientific studies, this peptide blend is utilized to: Study Growth Hormone Dynamics: Investigating the patterns and regulation of GH secretion. Metabolic Research: Understanding the role of GH in metabolism, including fat metabolism and muscle growth. Aging and Longevity Studies: Exploring the effects of GH on aging processes and potential therapeutic applications. Sleep and Recovery Research: Examining how GH influences sleep patterns and recovery processes. ⚠️ Important Considerations Research Use Only: These peptides are intended strictly for laboratory research and are not approved for human or veterinary use. Legal Status: The legality of purchasing and possessing these peptides varies by country and jurisdiction. It's essential to consult local regulations before acquiring them. Storage and Handling: Proper storage conditions are crucial to maintain peptide stability. Typically, lyophilized peptides should be stored at -20°C or colder and protected from light. Reconstitution should be done with appropriate solvents, and solutions should be stored at 4°C and used within a specified timeframe. Mod GRF 1-29 + Ipamorelin (5/5 mg) is primarily used in scientific research and clinical studies to investigate its effects on human growth hormone (GH) release and related metabolic functions. It is not FDA-approved for general medical use, but here are the commonly researched uses and potential applications: Stimulation of Growth Hormone (GH) Release Both peptides work synergistically to enhance the natural pulsatile release of GH from the pituitary gland. Mod GRF 1-29 initiates GH release, while Ipamorelin amplifies it by mimicking ghrelin. Anti-Aging Studies GH has regenerative effects on tissues, so researchers study this combo to explore its potential for: Improving skin elasticity Increasing energy levels Enhancing sleep quality Muscle Growth and Recovery (in studies) GH can help stimulate muscle protein synthesis and recovery. This combo is sometimes researched for its effects on lean muscle mass and exercise recovery. Fat Loss & Metabolic Support GH mobilizes stored fat, making this blend of interest in obesity and metabolic syndrome research. May support lipolysis (fat breakdown) in clinical models. Bone Density Studies GH supports bone mineralization. This combo is explored for potential applications in osteopenia/osteoporosis research. Sleep Improvement GH release is tied to deep sleep stages; researchers observe whether this combo improves sleep architecture and REM sleep. Modified GRF (1-29) acts to increase growth hormone production and release by binding to the growth-hormone-releasing hormone receptor (GHRHR) on cells in the anterior pituitary.

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Growth Hormone Secretagogues

Tesamorelin + CJC-1295 + Ipamorelin (6/3/3mg) FAST DELIVERY TO DOORSTEPS CJC-1295 is an incredibly effective peptide which works by stimulating the release of your own body's growth hormones (which drop quickly after the age of 30). Research has shown that CJC-1295 can increase growth hormone levels by 200-1000% and the elevated growth hormone production continued for up to 6 days. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Powder for Solution. Conclusion: Treatment with tesamorelin was generally well tolerated and resulted in sustained decreases in VAT and triglycerides over 52 weeks without aggravating glucose. Though effects on VAT are sustained during treatment for 52 weeks, these effects do not last beyond the duration of treatment. Signs of high blood sugar like confusion, feeling sleepy, unusual thirst or hunger, passing urine more often, flushing, fast breathing, or breath that smells like fruit. A fast heartbeat. Dizziness or passing out. Flushing. 1. Primary Medical & Performance Uses A. Fat Loss (Especially Visceral Fat) ✅ Tesamorelin (6mg): FDA-approved for HIV lipodystrophy (reduces abdominal fat). Targets stubborn belly fat even in non-HIV patients. ✅ CJC-1295 (3mg) + Ipamorelin (3mg): Amplifies growth hormone (GH) pulses for enhanced fat metabolism. Preserves muscle during calorie deficits. B. Muscle Growth & Recovery Boosts IGF-1 levels → Increases protein synthesis. Accelerates repair of tendons/ligaments (ideal for athletes). C. Anti-Aging & Longevity Improves skin elasticity (collagen stimulation). Enhances sleep quality (GH promotes deep sleep cycles). May support cognitive function (neuroprotective effects). D. Metabolic Health Improves insulin sensitivity (beneficial for prediabetes/metabolic syndrome). Lowers triglycerides (cardiovascular support). 2. Mechanism of Action Peptide Target Effect Tesamorelin GHRH Receptor (Pituitary) Stimulates GH release, specifically reduces visceral fat. CJC-1295 GHRH Receptor (Pituitary) Long-acting GH release (elevates IGF-1 for days). Ipamorelin Ghrelin Receptor Selective GH boost (no cortisol/prolactin spikes). Synergy: Tesamorelin targets fat stores, while CJC-1295 + Ipamorelin prolong GH benefits for muscle and recovery. 3. Dosage & Administration Standard Protocol Blend Ratio: 6mg Tesamorelin + 3mg CJC-1295 + 3mg Ipamorelin per vial. Daily Dose: Tesamorelin: 1–2mg/day (e.g., 1mg AM, 1mg PM). CJC-1295 + Ipamorelin: 100–300mcg each, 1–2x/day (post-workout or bedtime). Cycle Length: 8–12 weeks (followed by 4-week break). Reconstitution Mix with 2–3mL bacteriostatic water (for precise dosing). Storage: Refrigerate after reconstitution (stable for 4–6 weeks). 4. Expected Results & Timeline 📌 Weeks 1–4: Reduced bloating, improved sleep, increased energy. 📌 Weeks 4–8: Visible fat loss (especially abdomen), faster workout recovery. 📌 Weeks 8–12: Lean muscle definition, tighter skin, enhanced endurance. (Optimal with strength training + low-sugar diet.) Final Verdict ✅ Best for: Men/women targeting stubborn belly fat. Athletes wanting muscle preservation + recovery. Anti-aging (skin, cognition, longevity). Description Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Description Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Tesamorelin may sometimes be given at home to patients who do not need to be in a hospital or clinic. If you are using this medicine at home, your doctor or nurse will teach you how to prepare and inject the medicine. Be sure that you understand how to use the medicine. Tesamorelin injection comes with a patient information leaflet and patient instructions. Read the instructions and make sure you understand: How to prepare the injection. Proper use of disposable syringes. How to give the injection. How long the injection is stable. WE EXPORTY TO USA WE EXPORT TO UK WE EXPORT LO CANADA WE EXORT TO AUSTRALIA WE EXPORT ITALY WE EXPORT TO SINGAPORE

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Growth Hormone Secretagogues

Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. Tesamorelin + Ipamorelin (6mg/2mg) Blend: Medical Uses & Applications This peptide combination is primarily used for metabolic, anti-aging, and body composition benefits. Here’s a breakdown of its primary medical and off-label uses: 1. Approved Medical Use (FDA-Approved for HIV Lipodystrophy) ✅ Tesamorelin (6mg) FDA-approved to treat HIV-associated lipodystrophy (excess belly fat caused by antiretroviral therapy). Mechanism: Stimulates growth hormone (GH) release, reducing visceral fat. 2. Off-Label & Research-Based Uses A. Fat Loss & Metabolic Health Visceral fat reduction (even in non-HIV patients). Improves insulin sensitivity (potential for metabolic syndrome/type 2 diabetes support). B. Muscle Growth & Recovery Ipamorelin (2mg) is a growth hormone secretagogue (GHS) that: Boosts lean muscle mass. Enhances post-workout recovery. C. Anti-Aging & Longevity Increases collagen production (improves skin elasticity). May support cognitive function (GH plays a role in brain health). D. Injury & Tissue Repair Accelerates healing of tendons/ligaments (used by athletes). 3. Typical Treatment Protocol Dosage: Tesamorelin: 1-2mg/day (often 6mg total per week). Ipamorelin: 200-300mcg/day (2mg total per week). Administration: Subcutaneous injections (stomach or thigh). Cycle Length: 8-12 weeks (with breaks to avoid GH desensitization). 4. Key Benefits vs. Other Peptides Peptide Primary Use Pros Cons Tesamorelin FDA-approved fat loss Targets stubborn belly fat Expensive, requires prescri Final Verdict This blend is best for: ✔ Men/women targeting stubborn fat (especially abdominal). ✔ Athletes seeking muscle recovery & anti-aging benefits. ✔ Those wanting a safer alternative to synthetic GH. 4. Typical Dosage & Protocol Tesamorelin: 1-2mg/day (or 6mg/week). Ipamorelin: 200-300mcg/day (or 2mg/week). Administration: Subcutaneous injection (stomach/thigh). Cycle Length: 8-12 weeks (followed by a break to avoid GH resistance). 3. How It Works Tesamorelin → Stimulates pituitary GH release → Reduces visceral fat. 5. Expected Results & Timeline 📌 4-6 Weeks: Reduced belly fat, improved energy. 📌 8-12 Weeks: Visible muscle definition, better skin elasticity. 📌 Beyond 3 Months: Enhanced recovery, potential cognitive benefits. 5. Expected Results & Timeline 📌 4-6 Weeks: Reduced belly fat, improved energy. 📌 8-12 Weeks: Visible muscle definition, better skin elasticity. 📌 Beyond 3 Months: Enhanced recovery, potential cognitive benefits. 5. Expected Results & Timeline 📌 4-6 Weeks: Reduced belly fat, improved energy. 📌 8-12 Weeks: Visible muscle definition, better skin elasticity. 📌 Beyond 3 Months: Enhanced recovery, potential cognitive benefits. (Best when combined with diet + exercise) . Rare (serious): Increased blood sugar (caution for diabetics). Carpal tunnel syndrome (high doses). Final Verdict ✅ Best for: Men/women struggling with belly fat. Athletes seeking muscle recovery + anti-aging. Those wanting GH benefits without synthetic HGH risks. ❌ Not for: Quick fixes – requires consistent use for 2-3 months Tesamorelin, known for reducing abdominal fat in HIV patients with lipodystrophy, together with Ipamorelin, a growth hormone-releasing peptide, can enhance overall body composition improvements. Furthermore, both substances may work synergistically to boost muscle growth, fat loss, recovery, and anti-aging effects, maximizing the benefits of each peptide when used in tandem. Before taking this medicine You should not use tesamorelin if you are allergic to it, or if you have: cancer; a pituitary gland disorder; a history of pituitary gland tumor or surgery; a history of head injury or radiation treatment; or if you are pregnant. To make sure you can safely take tesamorelin, tell your doctor if you have any of these other conditions: a history of cancer or any tumor (either benign or malignant); heart disease, high blood pressure; kidney disease; diabetes, eye problems caused by diabetes; epilepsy asthma; migraine headaches; adrenal gland disorder; if you have ever had open heart surgery; or if you have any major illness, a recent trauma, or a medical emergency. FDA pregnancy category X. This medication can harm an unborn baby or cause birth defects. Do not use tesamorelin if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Women with HIV or AIDS should not breastfeed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk. WE EXPORT IN USA WE EXPORT IN UK WE EXPORT IN AUSTRALIA WE EXPORT IN CANADA WE EXPORT IN SINGAPORE

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