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Growth Hormone Secretagogues

The first 29 amino acids of GHRH were discovered to be as equally potent as its full 44 amino acid structure[1][2] This fragment became known as GRF (1-29). However, due to a rapid metabolic clearance analogues of GRF (1-29) were synthesized to enhance the biological activity and reduce the rapidity of metabolic clearance. These analogues were primarily created by substituting amino acids within the peptide structure for amino acids more resistant to enzymatic cleavage. One early analogue substituted the amino acid L-alanine (abbreviated as Ala or A) at the 2nd position of the peptide structure for its optical isomer (mirror image), D-alanine (abbreviated as D-Ala). This substitution resulted in a peptide bond between D-Ala and the 3rd amino acid in the structure aspartic acid (Asp) more able to resist rapid cleavage by the enzyme dipeptidyl peptidase-4, a cleavage which had previously led to an inactive peptide fragment.[3][4] This successful modification prompted the further creation of analogues with additional amino acid substitutions. Ipamorelin: A selective growth hormone secretagogue, Ipamorelin stimulates the release of GH by mimicking ghrelin's action on the ghrelin receptor. It is known for its specificity and minimal side effects compared to other GH-releasing peptides. Mod GRF 1-29 (CJC-1295 without DAC): This is a modified version of the first 29 amino acids of growth hormone-releasing hormone (GHRH). The modifications extend its half-life and enhance its ability to stimulate the pituitary gland to release GH. It is often used in research to study GH secretion patterns and related metabolic effects. ⚖️ Dosage and Composition The 5/5 mg blend indicates that each vial contains 5 mg of Mod GRF 1-29 and 5 mg of Ipamorelin, totaling 10 mg per vial. This combination is designed to provide a balanced stimulation of GH release, potentially offering synergistic effects when used in research protocols. 🔬 Research Applications In scientific studies, this peptide blend is utilized to: Study Growth Hormone Dynamics: Investigating the patterns and regulation of GH secretion. Metabolic Research: Understanding the role of GH in metabolism, including fat metabolism and muscle growth. Aging and Longevity Studies: Exploring the effects of GH on aging processes and potential therapeutic applications. Sleep and Recovery Research: Examining how GH influences sleep patterns and recovery processes. ⚠️ Important Considerations Research Use Only: These peptides are intended strictly for laboratory research and are not approved for human or veterinary use. Legal Status: The legality of purchasing and possessing these peptides varies by country and jurisdiction. It's essential to consult local regulations before acquiring them. Storage and Handling: Proper storage conditions are crucial to maintain peptide stability. Typically, lyophilized peptides should be stored at -20°C or colder and protected from light. Reconstitution should be done with appropriate solvents, and solutions should be stored at 4°C and used within a specified timeframe. Mod GRF 1-29 + Ipamorelin (5/5 mg) is primarily used in scientific research and clinical studies to investigate its effects on human growth hormone (GH) release and related metabolic functions. It is not FDA-approved for general medical use, but here are the commonly researched uses and potential applications: Stimulation of Growth Hormone (GH) Release Both peptides work synergistically to enhance the natural pulsatile release of GH from the pituitary gland. Mod GRF 1-29 initiates GH release, while Ipamorelin amplifies it by mimicking ghrelin. Anti-Aging Studies GH has regenerative effects on tissues, so researchers study this combo to explore its potential for: Improving skin elasticity Increasing energy levels Enhancing sleep quality Muscle Growth and Recovery (in studies) GH can help stimulate muscle protein synthesis and recovery. This combo is sometimes researched for its effects on lean muscle mass and exercise recovery. Fat Loss & Metabolic Support GH mobilizes stored fat, making this blend of interest in obesity and metabolic syndrome research. May support lipolysis (fat breakdown) in clinical models. Bone Density Studies GH supports bone mineralization. This combo is explored for potential applications in osteopenia/osteoporosis research. Sleep Improvement GH release is tied to deep sleep stages; researchers observe whether this combo improves sleep architecture and REM sleep. Modified GRF (1-29) acts to increase growth hormone production and release by binding to the growth-hormone-releasing hormone receptor (GHRHR) on cells in the anterior pituitary.

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Growth Hormone Secretagogues

CJC-1295 + Ipamorelin (5/5mg) PEPTIDE SCIENCE IS AVAILABLE IN INDIA CJC-1295 DAC, also known as DAC:GRF (short for drug affinity complex:growth hormone-releasing factor), is a synthetic analogue of growth hormone-releasing hormone (GHRH) (also known as growth hormone-releasing factor (GRF)) and a growth hormone secretagogue (GHS) which was developed by ConjuChem Biotechnologies.[1][2][3] It is a modified form of GHRH (1-29) with improved pharmacokinetics, especially in regard to half-life. 1. Primary Uses ✅ Muscle Growth & Performance Enhancement Boosts lean muscle mass by increasing protein synthesis. Speeds up recovery from workouts or injuries (tendons, ligaments). Popular among athletes, bodybuilders, and fitness enthusiasts. ✅ Fat Loss & Metabolism Enhances lipolysis (fat breakdown), especially stubborn belly fat. Improves insulin sensitivity (beneficial for metabolic health). Anti-Aging & Longevity Stimulates collagen production → Firmer skin, reduced wrinkles. Supports joint health → Reduces age-related stiffness/pain. May improve sleep quality & cognitive function (GH regulates brain health). ✅ Injury & Tissue Repair Accelerates healing of muscles, tendons, and cartilage. Used by athletes recovering from strains or surgeries. SKYBLUE INTERNATIONAL is a trusted global pharmaceutical export company specializing in the export of high-quality medicines. With a strong commitment to healthcare excellence, we supply a wide range of branded and generic medicines to countries including the USA, UK, Australia, UAE, Canada, Singapore, and the Philippines. Our focus is on reliability, compliance, and timely delivery to meet the global demand for affordable and effective medical solutions. Medicine WE EXPORT TO SINGAPORE WE EXPORT TO AUD WE EXPORT TO CAD WE EXPORT TO UK WE EXPORT TO UAE

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Growth Hormone Secretagogues

CJC-1295 DAC (5mg) FAST DELIVERY TO AUSTRALIA SKYBLUE INTERNATIONAL is a trusted global pharmaceutical export company specializing in the export of high-quality medicines. With a strong commitment to healthcare excellence, we supply a wide range of branded and generic medicines to countries including the USA, UK, Australia, UAE, Canada, Singapore, and the Philippines. Our focus is on reliability, compliance, and timely delivery to meet the global demand for affordable and effective medical solutions. Medicine 💊 USES : CJC-1295 DAC (Drug Affinity Complex) is a long-acting growth hormone-releasing hormone (GHRH) analog designed to elevate IGF-1 and growth hormone (GH) levels for days after a single injection. Below is a detailed breakdown of its primary applications, mechanisms, and protocols. Fat Loss & Metabolism Boosts lipolysis (fat breakdown), especially stubborn visceral fat. Improves insulin sensitivity → Supports metabolic health. Mechanism: Binds to GHRH receptors in the pituitary → sustained GH release (elevates IGF-1 for 5-7 days per dose). Half-life: 6-8 days (due to DAC modification, which prevents rapid breakdown). Key Difference vs. CJC-1295 (no DAC): CJC-1295 DAC → Long-lasting effects (fewer injections needed). Standard CJC-1295 → Shorter duration (requires daily dosing). Standard Protocol (5mg Vial) Reconstitution: Mix with 2mL bacteriostatic water (yields 2.5mg/mL). Dosing: Beginner: 1mg (0.4mL) 2x/week (e.g., Monday & Thursday). Advanced: 2mg (0.8mL) 2x/week (for maximum IGF-1 elevation). Cycle Length: 8-12 weeks (followed by a 4-week break). ✅ Best for: Athletes wanting sustained muscle growth & recovery. Men/women targeting fat loss + anti-aging benefits. Those who prefer fewer injections (vs. daily peptides). WE EXPORT IN UK WE EXPORT IN SINGAPORE WE EXPORT IN DUBAI WE EXPORT IN JAPAN WE EXPORT IN CANADA

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Growth Hormone Secretagogues

CJC-1295 + Hexarelin (5/5mg) FAST DELIVERY TO USA This peptide combination includes CJC-1295 (without DAC) and Hexarelin, two potent growth hormone-releasing agents that work synergistically to boost GH levels, enhance muscle growth, accelerate fat loss, and support recovery. to improve health and well-being in aging adults and those who desire better fitness results. Increased Muscle Mass: Enhanced growth hormone and IGF-1 levels support muscle growth and maintenance. Improved Recovery: Faster healing and reduced muscle soreness after workouts or injuries. Reduced Fat Storage: Accelerated fat metabolism for improved body composition. CJC 1295 has a longer-lasting effect. Hexarelin is best for short-term use when rapid results are required, but it carries a higher risk of side effects and tolerance. CJC-1295 DAC, also known as DAC:GRF (short for drug affinity complex:growth hormone-releasing factor), is a synthetic analogue of growth hormone-releasing hormone (GHRH) (also known as growth hormone-releasing factor (GRF)) and a growth hormone. What are the benefits of hexarelin? Hexarelin treatment significantly improved glucose and insulin intolerance and decreased plasma and liver triglycerides in MKR mice. FAST SHIPPING WORLD WIDE

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Growth Hormone Secretagogues

Tesamorelin + CJC-1295 + Ipamorelin (6/3/3mg) FAST DELIVERY TO DOORSTEPS CJC-1295 is an incredibly effective peptide which works by stimulating the release of your own body's growth hormones (which drop quickly after the age of 30). Research has shown that CJC-1295 can increase growth hormone levels by 200-1000% and the elevated growth hormone production continued for up to 6 days. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Powder for Solution. Conclusion: Treatment with tesamorelin was generally well tolerated and resulted in sustained decreases in VAT and triglycerides over 52 weeks without aggravating glucose. Though effects on VAT are sustained during treatment for 52 weeks, these effects do not last beyond the duration of treatment. Signs of high blood sugar like confusion, feeling sleepy, unusual thirst or hunger, passing urine more often, flushing, fast breathing, or breath that smells like fruit. A fast heartbeat. Dizziness or passing out. Flushing. 1. Primary Medical & Performance Uses A. Fat Loss (Especially Visceral Fat) ✅ Tesamorelin (6mg): FDA-approved for HIV lipodystrophy (reduces abdominal fat). Targets stubborn belly fat even in non-HIV patients. ✅ CJC-1295 (3mg) + Ipamorelin (3mg): Amplifies growth hormone (GH) pulses for enhanced fat metabolism. Preserves muscle during calorie deficits. B. Muscle Growth & Recovery Boosts IGF-1 levels → Increases protein synthesis. Accelerates repair of tendons/ligaments (ideal for athletes). C. Anti-Aging & Longevity Improves skin elasticity (collagen stimulation). Enhances sleep quality (GH promotes deep sleep cycles). May support cognitive function (neuroprotective effects). D. Metabolic Health Improves insulin sensitivity (beneficial for prediabetes/metabolic syndrome). Lowers triglycerides (cardiovascular support). 2. Mechanism of Action Peptide Target Effect Tesamorelin GHRH Receptor (Pituitary) Stimulates GH release, specifically reduces visceral fat. CJC-1295 GHRH Receptor (Pituitary) Long-acting GH release (elevates IGF-1 for days). Ipamorelin Ghrelin Receptor Selective GH boost (no cortisol/prolactin spikes). Synergy: Tesamorelin targets fat stores, while CJC-1295 + Ipamorelin prolong GH benefits for muscle and recovery. 3. Dosage & Administration Standard Protocol Blend Ratio: 6mg Tesamorelin + 3mg CJC-1295 + 3mg Ipamorelin per vial. Daily Dose: Tesamorelin: 1–2mg/day (e.g., 1mg AM, 1mg PM). CJC-1295 + Ipamorelin: 100–300mcg each, 1–2x/day (post-workout or bedtime). Cycle Length: 8–12 weeks (followed by 4-week break). Reconstitution Mix with 2–3mL bacteriostatic water (for precise dosing). Storage: Refrigerate after reconstitution (stable for 4–6 weeks). 4. Expected Results & Timeline 📌 Weeks 1–4: Reduced bloating, improved sleep, increased energy. 📌 Weeks 4–8: Visible fat loss (especially abdomen), faster workout recovery. 📌 Weeks 8–12: Lean muscle definition, tighter skin, enhanced endurance. (Optimal with strength training + low-sugar diet.) Final Verdict ✅ Best for: Men/women targeting stubborn belly fat. Athletes wanting muscle preservation + recovery. Anti-aging (skin, cognition, longevity). Description Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Description Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Tesamorelin may sometimes be given at home to patients who do not need to be in a hospital or clinic. If you are using this medicine at home, your doctor or nurse will teach you how to prepare and inject the medicine. Be sure that you understand how to use the medicine. Tesamorelin injection comes with a patient information leaflet and patient instructions. Read the instructions and make sure you understand: How to prepare the injection. Proper use of disposable syringes. How to give the injection. How long the injection is stable. WE EXPORTY TO USA WE EXPORT TO UK WE EXPORT LO CANADA WE EXORT TO AUSTRALIA WE EXPORT ITALY WE EXPORT TO SINGAPORE

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Erectile Dysfunction Medicines

Sildenafil Citrate CENFORCE 25mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, UK, EUROPE, UAE & GET 10% OFF ON BULK ORDER Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ When used: For men with occasional, moderate, or persistent erectile dysfunction, especially if lower doses (100 mg or less) weren't effective . Mechanism: It's a PDE‑5 inhibitor that increases cGMP to relax blood vessels and improve blood flow into the penis—helping to achieve and maintain an erection with sexual stimulation Sildenafil (the same medication) is also FDA-approved for PAH; Cenforce, like other sildenafil generics, is sometimes used off-label for this condition. Dosage & Administration Take one tablet (120 mg) about 30–60 minutes before planned sexual activity. Take one tablet (120 mg) about 30–60 minutes before planned sexual activity. Swallow whole with water; taking it on an empty stomach can speed up effects—heavy/fatty meals may delay onset. BUY NOW TO GET BEST OFFERS & DEALS

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Chronic Pain Treatment

Tapaday tapentadol 100mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ Brand Name: Tapaday 100 mg Generic Name: Tapentadol Hydrochloride 100 mg Composition: Each tablet contains: Tapentadol Hydrochloride equivalent to Tapentadol 100 mg Dosage Form: Oral tablet (Immediate Release or Extended Release — confirm based on labeling) Moderate to severe acute pain (e.g., post-surgical, traumatic injuries) Chronic pain osteoarthritis, lower back pain Sometimes used off-label for neuropathic pain (diabetic neuropathy), though extended-release is more common for this BUY IN USA PURCHASE IN USA WORLD WIDE SHIPPING

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Chronic Pain Treatment

Tapentadol 50mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ Tapentadol 50 mg is a prescription pain medication used primarily for the relief of moderate to severe pain. It belongs to a class of drugs called opioid analgesics and works in two ways: Manufacturer Sun Pharmaceutical Industries Ltd Salt Composition Tapentadol (50mg) Short Description Tydol 50 Tablet is a medicine used to treat moderate to severe acute pain in adults. Dosage Form Tablet Introduction Tydol 50 Tablet is a medicine used to treat many conditions such as headache, fever, period pain, toothache, and colds. It effectively alleviates pain when other treatments fail to relieve your pain. World wide shipping

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Chronic Pain Treatment

PREGABALIN CAPSULES 75mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Nervigesic 75mg Capsule belongs to the anti-epileptic group of medicines and can also be used to treat certain types of seizures (fits) in combination with other medicines. Additionally, it may also be prescribed to treat the symptoms of anxiety disorder if other medicines are not suitable. 1. Neuropathic Pain Treats nerve pain caused by: Diabetes (Diabetic Neuropathy) Spinal cord injury Post-herpetic neuralgia (after shingles) Sciatica Peripheral neuropathy Mechanism: Calms overactive nerves by modulating calcium channels in the nervous system. 2. Fibromyalgia Reduces widespread musculoskeletal pain, fatigue, and sleep problems common in fibromyalgia patients. 3. Epilepsy (Partial-Onset Seizures) Used as adjunct therapy with other anti-epileptic drugs to control focal seizures. 4. Generalized Anxiety Disorder (GAD) (Off-label in some countries) Helps reduce anxiety by acting on brain signaling, similar to benzodiazepines but without the same dependency profile.

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