Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Generic Name :- Kisspeptin-10 Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins 1. Stimulation of Gonadotropin-Releasing Hormone (GnRH) Kisspeptin-10 stimulates the hypothalamus to release GnRH, which then promotes the secretion of: Luteinizing hormone (LH) Follicle-stimulating hormone (FSH) This cascade is crucial for puberty onset, ovulation, and fertility regulation. 2. Fertility Research Used in assisted reproductive technologies (ART) and IVF studies to promote natural hormonal responses. Can potentially reduce the need for synthetic hormones like hCG. 3. Hypogonadism and Delayed Puberty Investigated as a treatment for hypogonadotropic hypogonadism (low LH/FSH due to low GnRH). May help restore reproductive function in affected individuals. 4. Polycystic Ovary Syndrome (PCOS) Studied for its role in correcting LH/FSH imbalances in PCOS patients. 5. Diagnostic Use Used to test pituitary function or the integrity of the hypothalamic-pituitary-gonadal (HPG) axis. BUY Kisspeptin-10 5mg IN CHEAP PRICE GET BEST OFFERS ON Kisspeptin-10 5mg FROM US SKYBLUE INTERNATIONAL

CENFORCE PRO SILDENAFIL CITRATE SUBLINGUAL TABLETS 100mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, UK, EUROPE, UAE & GET 20% OFF ON BULK ORDER Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ Cenforce Professional 100 mg is a fast-acting and effective sildenafil formulation designed for treating erectile dysfunction, with faster onset due to its chewable/sublingual delivery. It’s sometimes used off-label for pulmonary hypertension or blood pressure regulation, only on medical advice. It should be used once daily. USAGE :- Erectile Dysfunction (ED) in adult men Inhibits PDE‑5 → increases cGMP → relaxes smooth muscle → boosts blood flow to the penis during sexual arousal. Takes effect in about 30–60 minutes, lasting 4–6 hours, offering a reliable window for sexual activity. Sublingual/chewable tablet designed for faster absorption—dissolves under the tongue or is chewed and swallowed. Dosage :- Dose: One 100 mg tablet, no more than once every 24 hours Administration: Place under tongue or chew thoroughly, then swallow with water Can be taken with or without food, but avoid high-fat meals—they may delay onset Form Chewable/sublingual sildenafil 100 mg Onset 30–60 minutes Duration 4–6 hours Dose 1 tablet per 24 hours Use ED (primary), PAH or BP support (off‑label) Avoid with Nitrates, heavy meals, alcohol, grapefruit BUY IT NOW & GET BEST DEALS & DEALS

Melanotan-2 10mg, Peptide BUY IN CANADA, SINGAPORE, AUSTRALIA Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪ +917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ ✅ 1. Tanning Agent Primary use: Promotes skin darkening (tanning) by stimulating melanocytes to produce melanin. Users report a deeper, longer-lasting tan with less UV exposure (sunlight or tanning beds). Often used cosmetically to achieve a bronzed look while reducing skin cancer risk from prolonged sun exposure. ✅ 2. Libido Enhancement MT-II stimulates the hypothalamus, increasing libido and erectile function in some users. Studied as a potential treatment for erectile dysfunction (ED), especially where PDE5 inhibitors (like Viagra) are ineffective. ✅ 3. Fat Loss (Anecdotal) Some users report appetite suppression and increased fat metabolism, but scientific evidence is limited. These effects are likely secondary to central nervous system activity. Product Name Melanotan II (Melanotan-2, MT-II) Molecular Weight 1024.18 g/mol Peptide Purity ≥ 98% (HPLC) Appearance White to off-white lyophilized powder A full vial is usually 10mg, reconstituted with bacteriostatic water. Typical research dosing: Start low: 250–500 mcg/day (0.25–0.5mg) subcutaneously. Build up slowly to minimize side effects. Most users don’t exceed 1mg/day. Tanning agent Stimulates melanin for darker skin Libido enhancer Increases arousal and erectile response Appetite suppression May reduce food intake (anecdotal) BUY IN CANADA BUY IN SINGAPORE BUY IN AUSTRALIA BUY IN USA BUY IN ABU DHABI

Gonadorelin 10mg , Peptide USA FAST DELIVERY Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ 1. 🎯 Diagnostic Testing of the HPG Axis Used to assess pituitary function by measuring LH/FSH response—helpful in diagnosing hypogonadism or pituitary disorders . 2. 👩‍🔬 Female Infertility & Ovulation Induction Triggers ovulation in women with irregular periods Widely used in IVF and ART, often combined with hCG, to improve ovarian response and implantation rates 3. 👨 Male Hypogonadism & Delayed Puberty Stimulates testosterone and spermatogenesis in male hypogonadotropic hypogonadism and delayed puberty Helps prevent testicular atrophy during TRT and promotes natural LH/FSH production 4. 🧬 Hormone-Sensitive Cancers (Experimental) Explored in breast and prostate cancer to suppress estrogen/testosterone over long-term use . 5. 🦴 Bone, Muscle & Metabolic Health (Research) Preliminary studies show benefits for bone density, muscle strength, mood, and metabolic function via hormone regulation . 6. 🧠 Neurological & Cognitive Research Emerging research on GnRH analogues for potential applications in Alzheimer's disease and cognitive health Diagnosing HPG axis function Boosting fertility and managing reproductive disorders Treating male hormonal deficiencies and puberty delay Evaluating emerging roles in cancer, veterinary fertility, bone/muscle health, and neurology FAST DELIVERY FOR USA FAST DELIVERY FOR UK FAST DELIVERY FOR CANADA FAST DELIVERY FOR AUSTRALIA FAST DELIVERY FOR ABU DHABI FAST DELIVERY FOR SINGAPORE

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Generic Name Bremelanotide 1. Hypoactive Sexual Desire Disorder (HSDD) in Women FDA-approved in 2019 under the brand Vyleesi for pre-menopausal women with generalized HSDD unrelated to other medical or psychological condition Improves sexual desire, arousal, and reduces distress linked to low libido 2. Erectile Dysfunction (ED) in Men (Off‑Label) PT‑141 initiates erections via central nervous system pathways, increasing sexual desire and erection quality—even in men unresponsive to PDE‑5 inhibitors Demonstrated increased duration and rigidity of erections in trials 3. Sexual Arousal Support Boosts libido in both genders, addresses low sexual drive and arousal disorders, potentially enhancing orgasm quality and reducing refractory time Bremelanotide is a 7 amino acid peptide used to treat hypoactive sexual desire disorder in premenopausal women. Bremelanotide does not interact with alcohol. The mechanism by which bremelanotide's action on receptors translates to a clinical effect is still unknown. Bremelanotide was first described in the literature in 2003 when it was known by the investigational code PT-141.1 Since then it was investigated for its place in treating sexual dysfunction in men and women but is now only indicated for women.1,2,5 Other drugs used to treat female sexual dysfunction include flibanserin, estrogen, ospemifene, and prasterone. Bremelanotide was granted FDA approval Bremelanotide is an agonist of many melanocortin receptors which in order of potency are MC1R, MC4R, MC3R, MC5R, and MC2R.5 The mechanism by which agonism of these receptors translates to an improvement in hypoactive sexual desire disorder is currently unknown, however MC4R receptors are present in many areas of the central nervous system. MC3R and MC4R are found in the hypothalamus and are involved in food intake and energy homeostasis. Bremelanotide is a 7 amino acid and so its metabolism consists of multiple hydrolysis reactions.

Semax 30mg Peptide uses & doses USA fast delivery Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ 🧠 Primary Uses of Semax (30mg): 1. Cognitive Enhancement (Nootropic Use) Improves memory, focus, mental clarity, and learning ability Enhances executive function and creativity Often used by students, professionals, and biohackers 2. Neuroprotection Protects neurons from oxidative stress and damage Used in Russia after strokes, traumatic brain injuries, or brain surgeries 3. Mood and Stress Regulation Reduces symptoms of depression, anxiety, and mental fatigue Regulates stress by modulating the adrenal response and dopamine system 4. Treatment for ADHD & Cognitive Disorders Can support focus and impulse control in individuals with ADHD Sometimes used off-label to enhance dopaminergic transmission 5. Improved Recovery After Neurological Events Clinically used in post-stroke therapy in Russia Enhances cerebral blood flow and helps with neurological rehabilitation 6. Immune System Modulation May boost immune system response and inflammatory regulation Form Typical Dose Route Frequency 30mg vial (powder) 200–600 mcg per dose Intranasal (most common) 1–3 times per day

Contact Us on telegram or WhatsApp +917887449821‬ ‪+919168783773‬ +91 9529672584‬ +91 7499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ ✅ NAD⁺ (750 mg) – Uses and Benefits A 750 mg dose of NAD⁺ is considered a high oral dose for supplementation. At this level, it is often used for more targeted therapeutic effects or in anti-aging protocols, and may be part of high-dose oral or IV regimens. NAD⁺ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every cell that plays a crucial role in: Energy production (mitochondrial ATP synthesis) DNA repair Cell survival and aging Activation of sirtuins (longevity-related enzymes) 🧠 Emerging Research Areas NAD⁺ at this dose is being studied for: Parkinson’s, Alzheimer’s, and cognitive decline Chronic fatigue syndrome (ME/CFS) Immune function in aging (immunosenescence) NAD+ (750mg) improves mitochondrial health and slows the aging process. Neuroprotection (Brain Health): NAD+ (750mg) helps protect the health of your neurons and brain health for better mental clarity now and in the future. Mood Regulation: NAD+ is known to have positive effects on mood and mental well-being.

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ NAD+ (Nicotinamide adenine dinucleotide), in a 100mg dose from Peptide Science, is used for a variety of potential benefits related to cellular health and function. These include supporting energy production, DNA repair, and combating the effects of aging. NAD+ plays a crucial role in numerous cellular processes, making it a subject of interest for both its potential therapeutic applications and its role in healthy aging. Energy Production: NAD+ is essential for the cellular energy production process, particularly in the mitochondria. It acts as a coenzyme, facilitating the transfer of electrons in redox reactions, which are crucial for ATP (energy) production. DNA Repair: NAD+ is a substrate for enzymes called PARPs, which play a vital role in repairing DNA damage. Maintaining sufficient NAD+ levels can help ensure proper DNA repair and genomic stability. ✅ Primary Uses of NAD⁺ (100mg) Cellular Energy Production NAD⁺ is essential for mitochondrial function, helping convert nutrients into ATP (energy). Often used to combat fatigue or low energy levels. Healthy Aging & Longevity NAD⁺ levels decline with age. Supplementation may support DNA repair, cellular health, and overall longevity via sirtuin activation (especially SIRT1). Cognitive Function May enhance brain health, memory, and focus by supporting neuronal function and reducing oxidative stress. Metabolic Support Helps regulate metabolism, insulin sensitivity, and weight management. May support healthy blood sugar levels. Addiction & Withdrawal Support (High-dose clinical setting) NAD⁺ IV therapy is sometimes used in detox programs to ease withdrawal symptoms and improve mental clarity. 100 mg is a low dose; IV protocols often use much higher amounts. Skin and Anti-Aging Products Included in some topical formulations to promote skin cell repair and reduce signs of aging. Sirtuin Activation: NAD+ is also required by sirtuins, a class of proteins involved in gene regulation, cellular stress responses, and potentially, longevity. Anti-Aging: Because NAD+ is involved in so many fundamental cellular processes, its decline with age is linked to various age-related changes. Maintaining NAD+ levels through supplementation is being explored as a way to potentially mitigate some of these changes and promote healthy aging.

Tirzepatide (60mg) FAST DELIVERY TO FLORIDA Contact Us on telegram or WhatsApp +917887449821 +919168783773 +91 9529672584 +91 7499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Tirzepatide (60mg) Uses: Type 2 Diabetes: Tirzepatide is used to improve blood sugar control in adults with type 2 diabetes, often used with diet and exercise. Weight Management: It is also used for weight loss, particularly in adults who are overweight or obese, or who have weight-related medical problems. a synthetic peptide, a dual agonist for both GLP-1 (glucagon-like peptide 1) and GIP (glucose-dependent insulinotropic polypeptide) receptors. It is used to treat type 2 diabetes and may also be used for weight management. It works by mimicking the effects of two hormones involved in glucose regulation and appetite control, helping to lower blood sugar levels and potentially leading to weight loss. Tirzepatide is administered as a once-weekly subcutaneous injection. Dual Action: Tirzepatide targets both GLP-1 and GIP receptors, enhancing insulin sensitivity and potentially leading to weight loss. Mechanism of Action: It increases insulin secretion when blood sugar is high, lowers liver glucose production, and slows down food movement through the digestive tract, contributing to blood sugar control and weight loss. Administration: Tirzepatide is a subcutaneous injection, given once weekly. Potential Side Effects: Common side effects include nausea, vomiting, diarrhea, and constipation, especially during the initial dose escalation phase. Top Benefits of Tirzepatide :- Powerful Blood Sugar Control (Type 2 Diabetes) Lowers HbA1c levels significantly (up to 2.4% reduction) Helps regulate insulin and glucagon more effectively than GLP-1 drugs alone Outperforms other drugs like semaglutide and insulin degludec in trials