The first 29 amino acids of GHRH were discovered to be as equally potent as its full 44 amino acid structure[1][2] This fragment became known as GRF (1-29). However, due to a rapid metabolic clearance analogues of GRF (1-29) were synthesized to enhance the biological activity and reduce the rapidity of metabolic clearance. These analogues were primarily created by substituting amino acids within the peptide structure for amino acids more resistant to enzymatic cleavage. One early analogue substituted the amino acid L-alanine (abbreviated as Ala or A) at the 2nd position of the peptide structure for its optical isomer (mirror image), D-alanine (abbreviated as D-Ala). This substitution resulted in a peptide bond between D-Ala and the 3rd amino acid in the structure aspartic acid (Asp) more able to resist rapid cleavage by the enzyme dipeptidyl peptidase-4, a cleavage which had previously led to an inactive peptide fragment.[3][4] This successful modification prompted the further creation of analogues with additional amino acid substitutions. Ipamorelin: A selective growth hormone secretagogue, Ipamorelin stimulates the release of GH by mimicking ghrelin's action on the ghrelin receptor. It is known for its specificity and minimal side effects compared to other GH-releasing peptides. Mod GRF 1-29 (CJC-1295 without DAC): This is a modified version of the first 29 amino acids of growth hormone-releasing hormone (GHRH). The modifications extend its half-life and enhance its ability to stimulate the pituitary gland to release GH. It is often used in research to study GH secretion patterns and related metabolic effects. ⚖️ Dosage and Composition The 5/5 mg blend indicates that each vial contains 5 mg of Mod GRF 1-29 and 5 mg of Ipamorelin, totaling 10 mg per vial. This combination is designed to provide a balanced stimulation of GH release, potentially offering synergistic effects when used in research protocols. 🔬 Research Applications In scientific studies, this peptide blend is utilized to: Study Growth Hormone Dynamics: Investigating the patterns and regulation of GH secretion. Metabolic Research: Understanding the role of GH in metabolism, including fat metabolism and muscle growth. Aging and Longevity Studies: Exploring the effects of GH on aging processes and potential therapeutic applications. Sleep and Recovery Research: Examining how GH influences sleep patterns and recovery processes. ⚠️ Important Considerations Research Use Only: These peptides are intended strictly for laboratory research and are not approved for human or veterinary use. Legal Status: The legality of purchasing and possessing these peptides varies by country and jurisdiction. It's essential to consult local regulations before acquiring them. Storage and Handling: Proper storage conditions are crucial to maintain peptide stability. Typically, lyophilized peptides should be stored at -20°C or colder and protected from light. Reconstitution should be done with appropriate solvents, and solutions should be stored at 4°C and used within a specified timeframe. Mod GRF 1-29 + Ipamorelin (5/5 mg) is primarily used in scientific research and clinical studies to investigate its effects on human growth hormone (GH) release and related metabolic functions. It is not FDA-approved for general medical use, but here are the commonly researched uses and potential applications: Stimulation of Growth Hormone (GH) Release Both peptides work synergistically to enhance the natural pulsatile release of GH from the pituitary gland. Mod GRF 1-29 initiates GH release, while Ipamorelin amplifies it by mimicking ghrelin. Anti-Aging Studies GH has regenerative effects on tissues, so researchers study this combo to explore its potential for: Improving skin elasticity Increasing energy levels Enhancing sleep quality Muscle Growth and Recovery (in studies) GH can help stimulate muscle protein synthesis and recovery. This combo is sometimes researched for its effects on lean muscle mass and exercise recovery. Fat Loss & Metabolic Support GH mobilizes stored fat, making this blend of interest in obesity and metabolic syndrome research. May support lipolysis (fat breakdown) in clinical models. Bone Density Studies GH supports bone mineralization. This combo is explored for potential applications in osteopenia/osteoporosis research. Sleep Improvement GH release is tied to deep sleep stages; researchers observe whether this combo improves sleep architecture and REM sleep. Modified GRF (1-29) acts to increase growth hormone production and release by binding to the growth-hormone-releasing hormone receptor (GHRHR) on cells in the anterior pituitary.

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Generic Name Bremelanotide 1. Hypoactive Sexual Desire Disorder (HSDD) in Women FDA-approved in 2019 under the brand Vyleesi for pre-menopausal women with generalized HSDD unrelated to other medical or psychological condition Improves sexual desire, arousal, and reduces distress linked to low libido 2. Erectile Dysfunction (ED) in Men (Off‑Label) PT‑141 initiates erections via central nervous system pathways, increasing sexual desire and erection quality—even in men unresponsive to PDE‑5 inhibitors Demonstrated increased duration and rigidity of erections in trials 3. Sexual Arousal Support Boosts libido in both genders, addresses low sexual drive and arousal disorders, potentially enhancing orgasm quality and reducing refractory time Bremelanotide is a 7 amino acid peptide used to treat hypoactive sexual desire disorder in premenopausal women. Bremelanotide does not interact with alcohol. The mechanism by which bremelanotide's action on receptors translates to a clinical effect is still unknown. Bremelanotide was first described in the literature in 2003 when it was known by the investigational code PT-141.1 Since then it was investigated for its place in treating sexual dysfunction in men and women but is now only indicated for women.1,2,5 Other drugs used to treat female sexual dysfunction include flibanserin, estrogen, ospemifene, and prasterone. Bremelanotide was granted FDA approval Bremelanotide is an agonist of many melanocortin receptors which in order of potency are MC1R, MC4R, MC3R, MC5R, and MC2R.5 The mechanism by which agonism of these receptors translates to an improvement in hypoactive sexual desire disorder is currently unknown, however MC4R receptors are present in many areas of the central nervous system. MC3R and MC4R are found in the hypothalamus and are involved in food intake and energy homeostasis. Bremelanotide is a 7 amino acid and so its metabolism consists of multiple hydrolysis reactions.

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ TB-500 (10mg) It is a first-in-class peptide candidate that promotes the following*: Endothelial (blood vessels) cell differentiation Angiogenesis (growth of new blood cells from pre-existing vessels) in dermal tissues Keratinocyte migration Collagen deposition; and Decreases inflammation. TB-500 (10 mg) is a synthetic version of a naturally occurring peptide called Thymosin Beta-4, specifically designed to support tissue regeneration, healing, and inflammation reduction. It is widely used in sports medicine, biohacking, and research protocols for injury recovery and performance support. Name: TB-500 (Thymosin Beta-4 Acetate, synthetic fragment) Structure: 43 amino acid peptide (active portion of full Thymosin Beta-4) Form: Lyophilized powder, typically in 10 mg vials for ease of multi-dose use TB-500 (10 mg) 🧠 1. Tissue Repair and Regeneration Promotes healing of muscles, tendons, and ligaments Facilitates angiogenesis (formation of new blood vessels) to speed tissue recovery Improves cell migration and differentiation to injury sites 🦴 2. Joint, Ligament & Tendon Recovery Used for chronic joint pain, arthritis, or tendonitis (e.g., elbow, shoulder, knee) Often combined with BPC-157 for synergistic musculoskeletal healing 💪 3. Muscle Recovery and Performance Enhances muscle growth, flexibility, and strength restoration Reduces inflammation and helps repair overtrained or injured muscle tissue 🧬 4. Hair Growth (Experimental) May support hair follicle regeneration and increase hair growth phase duration Sometimes used in off-label protocols for hair loss 🩹 5. Wound Healing Speeds dermal healing of cuts, abrasions, and post-surgical wounds Increases keratinocyte and endothelial cell movement to wound site 💊 Primary Uses of TB-500 (10 mg) 🧠 1. Tissue Repair and Regeneration Promotes healing of muscles, tendons, and ligaments Facilitates angiogenesis (formation of new blood vessels) to speed tissue recovery Improves cell migration and differentiation to injury sites 🦴 2. Joint, Ligament & Tendon Recovery Used for chronic joint pain, arthritis, or tendonitis (e.g., elbow, shoulder, knee) Often combined with BPC-157 for synergistic musculoskeletal healing 💪 3. Muscle Recovery and Performance Enhances muscle growth, flexibility, and strength restoration Reduces inflammation and helps repair overtrained or injured muscle tissue 🧬 4. Hair Growth (Experimental) May support hair follicle regeneration and increase hair growth phase duration Sometimes used in off-label protocols for hair loss 🩹 5. Wound Healing Speeds dermal healing of cuts, abrasions, and post-surgical wounds Increases keratinocyte and endothelial cell movement to wound site BUY IT FROM https://www.skyblueinternationals.com/

Contact Us on telegram or WhatsApp +917887449821‬ +919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ MOTS-c (5mg) :- MOTS-c (5mg), a mitochondrial-derived peptide, is being investigated for its potential to treat metabolic disorders, improve muscle function, and promote healthy aging. It's believed to play a role in regulating energy metabolism, insulin resistance, and the inflammatory response. While research is ongoing, MOTS-c is being explored as a potential therapeutic strategy for conditions like obesity, age-related diseases, and even osteoporosis. MOTS-c stands for 'Mitochondrial Open Reading Frame of the 12S rRNA-c'. It is a 16-amino acid peptide that acts like a hormone, influencing metabolism, stress response, and cellular energy production. Unlike other peptides, it originates from mitochondrial DNA, not nuclear DNA. Exercise and Aging: MOTS-c can enhance exercise endurance and potentially counteract age-related muscle decline Bone Health: Osteoporosis: MOTS-c has been shown to inhibit osteoclast activity and reduce bone loss, suggesting a potential role in preventing and treating osteoporosis. Other Potential Benefits: Anti-inflammatory Effects: MOTS-c may help regulate the inflammatory response, which is implicated in various diseases. Brain Health: Research indicates MOTS-c may improve cognitive function and memory. Cardiovascular Health: MOTS-c has been linked to improved heart function and blood vessel health. 🧠 1. Anti-Aging & Longevity Increases mitochondrial efficiency. Activates AMPK (AMP-activated protein kinase), a key longevity pathway. Promotes cellular stress resistance (e.g., oxidative and metabolic stress). ⚡ 2. Metabolic Health Improves insulin sensitivity and glucose metabolism. Supports weight loss and fat oxidation. Reduces markers of metabolic syndrome and type 2 diabetes in animal models. 💪 3. Exercise & Performance Enhancement Enhances endurance and physical capacity. Protects muscles from exercise-induced stress. Mimics some effects of exercise even without activity ('exercise mimetic'). 🧬 4. Mitochondrial Health Promotes mitochondrial biogenesis. Helps maintain mitochondrial DNA integrity and function under stress. 🧠 5. Neuroprotection (early-stage research) May protect brain cells from oxidative and metabolic damage. MOTS-c (5mg) fast delivery in london

CJC-1295 DAC (5mg) FAST DELIVERY TO AUSTRALIA SKYBLUE INTERNATIONAL is a trusted global pharmaceutical export company specializing in the export of high-quality medicines. With a strong commitment to healthcare excellence, we supply a wide range of branded and generic medicines to countries including the USA, UK, Australia, UAE, Canada, Singapore, and the Philippines. Our focus is on reliability, compliance, and timely delivery to meet the global demand for affordable and effective medical solutions. Medicine 💊 USES : CJC-1295 DAC (Drug Affinity Complex) is a long-acting growth hormone-releasing hormone (GHRH) analog designed to elevate IGF-1 and growth hormone (GH) levels for days after a single injection. Below is a detailed breakdown of its primary applications, mechanisms, and protocols. Fat Loss & Metabolism Boosts lipolysis (fat breakdown), especially stubborn visceral fat. Improves insulin sensitivity → Supports metabolic health. Mechanism: Binds to GHRH receptors in the pituitary → sustained GH release (elevates IGF-1 for 5-7 days per dose). Half-life: 6-8 days (due to DAC modification, which prevents rapid breakdown). Key Difference vs. CJC-1295 (no DAC): CJC-1295 DAC → Long-lasting effects (fewer injections needed). Standard CJC-1295 → Shorter duration (requires daily dosing). Standard Protocol (5mg Vial) Reconstitution: Mix with 2mL bacteriostatic water (yields 2.5mg/mL). Dosing: Beginner: 1mg (0.4mL) 2x/week (e.g., Monday & Thursday). Advanced: 2mg (0.8mL) 2x/week (for maximum IGF-1 elevation). Cycle Length: 8-12 weeks (followed by a 4-week break). ✅ Best for: Athletes wanting sustained muscle growth & recovery. Men/women targeting fat loss + anti-aging benefits. Those who prefer fewer injections (vs. daily peptides). WE EXPORT IN UK WE EXPORT IN SINGAPORE WE EXPORT IN DUBAI WE EXPORT IN JAPAN WE EXPORT IN CANADA

CJC-1295 + Hexarelin (5/5mg) FAST DELIVERY TO USA This peptide combination includes CJC-1295 (without DAC) and Hexarelin, two potent growth hormone-releasing agents that work synergistically to boost GH levels, enhance muscle growth, accelerate fat loss, and support recovery. to improve health and well-being in aging adults and those who desire better fitness results. Increased Muscle Mass: Enhanced growth hormone and IGF-1 levels support muscle growth and maintenance. Improved Recovery: Faster healing and reduced muscle soreness after workouts or injuries. Reduced Fat Storage: Accelerated fat metabolism for improved body composition. CJC 1295 has a longer-lasting effect. Hexarelin is best for short-term use when rapid results are required, but it carries a higher risk of side effects and tolerance. CJC-1295 DAC, also known as DAC:GRF (short for drug affinity complex:growth hormone-releasing factor), is a synthetic analogue of growth hormone-releasing hormone (GHRH) (also known as growth hormone-releasing factor (GRF)) and a growth hormone. What are the benefits of hexarelin? Hexarelin treatment significantly improved glucose and insulin intolerance and decreased plasma and liver triglycerides in MKR mice. FAST SHIPPING WORLD WIDE

CJC-1295 + Ipamorelin (5/5mg) PEPTIDE SCIENCE IS AVAILABLE IN INDIA CJC-1295 DAC, also known as DAC:GRF (short for drug affinity complex:growth hormone-releasing factor), is a synthetic analogue of growth hormone-releasing hormone (GHRH) (also known as growth hormone-releasing factor (GRF)) and a growth hormone secretagogue (GHS) which was developed by ConjuChem Biotechnologies.[1][2][3] It is a modified form of GHRH (1-29) with improved pharmacokinetics, especially in regard to half-life. 1. Primary Uses ✅ Muscle Growth & Performance Enhancement Boosts lean muscle mass by increasing protein synthesis. Speeds up recovery from workouts or injuries (tendons, ligaments). Popular among athletes, bodybuilders, and fitness enthusiasts. ✅ Fat Loss & Metabolism Enhances lipolysis (fat breakdown), especially stubborn belly fat. Improves insulin sensitivity (beneficial for metabolic health). Anti-Aging & Longevity Stimulates collagen production → Firmer skin, reduced wrinkles. Supports joint health → Reduces age-related stiffness/pain. May improve sleep quality & cognitive function (GH regulates brain health). ✅ Injury & Tissue Repair Accelerates healing of muscles, tendons, and cartilage. Used by athletes recovering from strains or surgeries. SKYBLUE INTERNATIONAL is a trusted global pharmaceutical export company specializing in the export of high-quality medicines. With a strong commitment to healthcare excellence, we supply a wide range of branded and generic medicines to countries including the USA, UK, Australia, UAE, Canada, Singapore, and the Philippines. Our focus is on reliability, compliance, and timely delivery to meet the global demand for affordable and effective medical solutions. Medicine WE EXPORT TO SINGAPORE WE EXPORT TO AUD WE EXPORT TO CAD WE EXPORT TO UK WE EXPORT TO UAE

Tesamorelin + CJC-1295 + Ipamorelin (6/3/3mg) FAST DELIVERY TO DOORSTEPS CJC-1295 is an incredibly effective peptide which works by stimulating the release of your own body's growth hormones (which drop quickly after the age of 30). Research has shown that CJC-1295 can increase growth hormone levels by 200-1000% and the elevated growth hormone production continued for up to 6 days. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Powder for Solution. Conclusion: Treatment with tesamorelin was generally well tolerated and resulted in sustained decreases in VAT and triglycerides over 52 weeks without aggravating glucose. Though effects on VAT are sustained during treatment for 52 weeks, these effects do not last beyond the duration of treatment. Signs of high blood sugar like confusion, feeling sleepy, unusual thirst or hunger, passing urine more often, flushing, fast breathing, or breath that smells like fruit. A fast heartbeat. Dizziness or passing out. Flushing. 1. Primary Medical & Performance Uses A. Fat Loss (Especially Visceral Fat) ✅ Tesamorelin (6mg): FDA-approved for HIV lipodystrophy (reduces abdominal fat). Targets stubborn belly fat even in non-HIV patients. ✅ CJC-1295 (3mg) + Ipamorelin (3mg): Amplifies growth hormone (GH) pulses for enhanced fat metabolism. Preserves muscle during calorie deficits. B. Muscle Growth & Recovery Boosts IGF-1 levels → Increases protein synthesis. Accelerates repair of tendons/ligaments (ideal for athletes). C. Anti-Aging & Longevity Improves skin elasticity (collagen stimulation). Enhances sleep quality (GH promotes deep sleep cycles). May support cognitive function (neuroprotective effects). D. Metabolic Health Improves insulin sensitivity (beneficial for prediabetes/metabolic syndrome). Lowers triglycerides (cardiovascular support). 2. Mechanism of Action Peptide Target Effect Tesamorelin GHRH Receptor (Pituitary) Stimulates GH release, specifically reduces visceral fat. CJC-1295 GHRH Receptor (Pituitary) Long-acting GH release (elevates IGF-1 for days). Ipamorelin Ghrelin Receptor Selective GH boost (no cortisol/prolactin spikes). Synergy: Tesamorelin targets fat stores, while CJC-1295 + Ipamorelin prolong GH benefits for muscle and recovery. 3. Dosage & Administration Standard Protocol Blend Ratio: 6mg Tesamorelin + 3mg CJC-1295 + 3mg Ipamorelin per vial. Daily Dose: Tesamorelin: 1–2mg/day (e.g., 1mg AM, 1mg PM). CJC-1295 + Ipamorelin: 100–300mcg each, 1–2x/day (post-workout or bedtime). Cycle Length: 8–12 weeks (followed by 4-week break). Reconstitution Mix with 2–3mL bacteriostatic water (for precise dosing). Storage: Refrigerate after reconstitution (stable for 4–6 weeks). 4. Expected Results & Timeline 📌 Weeks 1–4: Reduced bloating, improved sleep, increased energy. 📌 Weeks 4–8: Visible fat loss (especially abdomen), faster workout recovery. 📌 Weeks 8–12: Lean muscle definition, tighter skin, enhanced endurance. (Optimal with strength training + low-sugar diet.) Final Verdict ✅ Best for: Men/women targeting stubborn belly fat. Athletes wanting muscle preservation + recovery. Anti-aging (skin, cognition, longevity). Description Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Description Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Tesamorelin may sometimes be given at home to patients who do not need to be in a hospital or clinic. If you are using this medicine at home, your doctor or nurse will teach you how to prepare and inject the medicine. Be sure that you understand how to use the medicine. Tesamorelin injection comes with a patient information leaflet and patient instructions. Read the instructions and make sure you understand: How to prepare the injection. Proper use of disposable syringes. How to give the injection. How long the injection is stable. WE EXPORTY TO USA WE EXPORT TO UK WE EXPORT LO CANADA WE EXORT TO AUSTRALIA WE EXPORT ITALY WE EXPORT TO SINGAPORE

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