The first 29 amino acids of GHRH were discovered to be as equally potent as its full 44 amino acid structure[1][2] This fragment became known as GRF (1-29). However, due to a rapid metabolic clearance analogues of GRF (1-29) were synthesized to enhance the biological activity and reduce the rapidity of metabolic clearance. These analogues were primarily created by substituting amino acids within the peptide structure for amino acids more resistant to enzymatic cleavage. One early analogue substituted the amino acid L-alanine (abbreviated as Ala or A) at the 2nd position of the peptide structure for its optical isomer (mirror image), D-alanine (abbreviated as D-Ala). This substitution resulted in a peptide bond between D-Ala and the 3rd amino acid in the structure aspartic acid (Asp) more able to resist rapid cleavage by the enzyme dipeptidyl peptidase-4, a cleavage which had previously led to an inactive peptide fragment.[3][4] This successful modification prompted the further creation of analogues with additional amino acid substitutions. Ipamorelin: A selective growth hormone secretagogue, Ipamorelin stimulates the release of GH by mimicking ghrelin's action on the ghrelin receptor. It is known for its specificity and minimal side effects compared to other GH-releasing peptides. Mod GRF 1-29 (CJC-1295 without DAC): This is a modified version of the first 29 amino acids of growth hormone-releasing hormone (GHRH). The modifications extend its half-life and enhance its ability to stimulate the pituitary gland to release GH. It is often used in research to study GH secretion patterns and related metabolic effects. ⚖️ Dosage and Composition The 5/5 mg blend indicates that each vial contains 5 mg of Mod GRF 1-29 and 5 mg of Ipamorelin, totaling 10 mg per vial. This combination is designed to provide a balanced stimulation of GH release, potentially offering synergistic effects when used in research protocols. 🔬 Research Applications In scientific studies, this peptide blend is utilized to: Study Growth Hormone Dynamics: Investigating the patterns and regulation of GH secretion. Metabolic Research: Understanding the role of GH in metabolism, including fat metabolism and muscle growth. Aging and Longevity Studies: Exploring the effects of GH on aging processes and potential therapeutic applications. Sleep and Recovery Research: Examining how GH influences sleep patterns and recovery processes. ⚠️ Important Considerations Research Use Only: These peptides are intended strictly for laboratory research and are not approved for human or veterinary use. Legal Status: The legality of purchasing and possessing these peptides varies by country and jurisdiction. It's essential to consult local regulations before acquiring them. Storage and Handling: Proper storage conditions are crucial to maintain peptide stability. Typically, lyophilized peptides should be stored at -20°C or colder and protected from light. Reconstitution should be done with appropriate solvents, and solutions should be stored at 4°C and used within a specified timeframe. Mod GRF 1-29 + Ipamorelin (5/5 mg) is primarily used in scientific research and clinical studies to investigate its effects on human growth hormone (GH) release and related metabolic functions. It is not FDA-approved for general medical use, but here are the commonly researched uses and potential applications: Stimulation of Growth Hormone (GH) Release Both peptides work synergistically to enhance the natural pulsatile release of GH from the pituitary gland. Mod GRF 1-29 initiates GH release, while Ipamorelin amplifies it by mimicking ghrelin. Anti-Aging Studies GH has regenerative effects on tissues, so researchers study this combo to explore its potential for: Improving skin elasticity Increasing energy levels Enhancing sleep quality Muscle Growth and Recovery (in studies) GH can help stimulate muscle protein synthesis and recovery. This combo is sometimes researched for its effects on lean muscle mass and exercise recovery. Fat Loss & Metabolic Support GH mobilizes stored fat, making this blend of interest in obesity and metabolic syndrome research. May support lipolysis (fat breakdown) in clinical models. Bone Density Studies GH supports bone mineralization. This combo is explored for potential applications in osteopenia/osteoporosis research. Sleep Improvement GH release is tied to deep sleep stages; researchers observe whether this combo improves sleep architecture and REM sleep. Modified GRF (1-29) acts to increase growth hormone production and release by binding to the growth-hormone-releasing hormone receptor (GHRHR) on cells in the anterior pituitary.

TIZARO TIRZEPATIDE 7.5mg BUY'S IN CANADA, SINGAPORE, AUSTRALIA, USA, EUROPE, UAE Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ DISCRIBTION :- Type 2 Diabetes Mellitus (T2DM) Helps lower blood sugar (HbA1c) effectively Improves insulin sensitivity and secretion Reduces fasting and post-meal glucose spikes ➡️ Often used when 5 mg dose is tolerated well but greater glycemic control is needed. Weight Loss / Obesity Treatment Used for chronic weight management in: Adults with BMI ≥30, or BMI ≥27 with obesity-related conditions (diabetes, hypertension, etc.) At 7.5 mg, patients often report: Stronger appetite suppression Increased fat loss Accelerated body weight reduction vs lower doses ❤️ Cardiometabolic Benefits (Research-based) Helps reduce: LDL cholesterol and triglycerides Blood pressure Systemic inflammation (CRP) 7.5 mg Once weekly (SC injection) Injection sites Abdomen, thigh, upper arm Titration path 2.5 mg → 5 mg → 7.5 mg Max approved dose Up to 15 mg (in some proto How Tizaro Works (Mechanism) GLP-1 action: Enhances insulin release, slows gastric emptying, reduces appetite GIP action: Increases fat metabolism, improves insulin response Together, this dual pathway provides: Superior glucose control Greater weight loss vs other GLP-1 drugs (like semaglutide) BUY FROM US WORLD WIDE SHIPPING WITH GOOD PACKAGING CONTACT US FOR BEST OFFERS & DEALS

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ 🍼 Reproductive Health Stimulates uterine contractions during labor and supports milk ejection in breastfeeding. Oxytocin 10mg Boosts trust, empathy, and strengthens interpersonal connection Investigational in treating autism, social anxiety, depression, and PTSD via intranasal delivery. Reduces cortisol levels, improves stress resilience, relaxation, and mood balance. Lowers blood pressure, reduces inflammation, and shows anti-sepsis potential. Promotes wound healing, tissue repair, and pain relief. Reproductive roles (labor, lactation) Emotional and social behavior modulation Stress, mood, and mental health interventions Tissue healing and pain relief Metabolic enhancements (weight, glucose) Sexual and intimacy functions Administration & Dosage :- Injectable (subcutaneous/intramuscular): Used in reproductive health and healing research; dosages vary widely based on study protocols . we export in USA we export in UK we export in SINGAORE we export in AUSTRALIA we export in CHAINA we export in CANADA WORLD WIDE SHIPPING IN BEST DEALS..

Epithalon (10mg) Peptide Science USE & BENIFITS FAST DELIVERY IN USA Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ 🧠 1. Anti-Aging & Longevity Stimulates telomerase activity, which helps protect DNA by lengthening telomeres — potentially slowing cellular aging. May extend lifespan in animal studies. 🌙 2. Improves Sleep Quality Helps regulate melatonin production via the pineal gland. Used to normalize circadian rhythms in older adults or shift workers. 🧬 3. Supports Cellular Regeneration Encourages healthy cell division and regeneration. May reduce DNA damage associated with aging. 💪 4. Immune System Modulation Boosts T-cell production and immune response in aging individuals. May reduce inflammation and improve resistance to infections. 🧠 5. Neuroprotective Effects Shown in studies to protect neurons and brain function. Possible improvements in mood, memory, and cognitive clarity. ❤️ 6. Cardiovascular & Metabolic Health Potential to reduce oxidative stress and regulate blood pressure. May improve glucose metabolism and reduce risk of age-related diseases. BUY IN TEXAS NEW YORK BUY IN CALIFORNIA BUY IN CHICAGO

Contact Us on telegram or WhatsApp +917887449821‬ +919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ MOTS-c (5mg) :- MOTS-c (5mg), a mitochondrial-derived peptide, is being investigated for its potential to treat metabolic disorders, improve muscle function, and promote healthy aging. It's believed to play a role in regulating energy metabolism, insulin resistance, and the inflammatory response. While research is ongoing, MOTS-c is being explored as a potential therapeutic strategy for conditions like obesity, age-related diseases, and even osteoporosis. MOTS-c stands for 'Mitochondrial Open Reading Frame of the 12S rRNA-c'. It is a 16-amino acid peptide that acts like a hormone, influencing metabolism, stress response, and cellular energy production. Unlike other peptides, it originates from mitochondrial DNA, not nuclear DNA. Exercise and Aging: MOTS-c can enhance exercise endurance and potentially counteract age-related muscle decline Bone Health: Osteoporosis: MOTS-c has been shown to inhibit osteoclast activity and reduce bone loss, suggesting a potential role in preventing and treating osteoporosis. Other Potential Benefits: Anti-inflammatory Effects: MOTS-c may help regulate the inflammatory response, which is implicated in various diseases. Brain Health: Research indicates MOTS-c may improve cognitive function and memory. Cardiovascular Health: MOTS-c has been linked to improved heart function and blood vessel health. 🧠 1. Anti-Aging & Longevity Increases mitochondrial efficiency. Activates AMPK (AMP-activated protein kinase), a key longevity pathway. Promotes cellular stress resistance (e.g., oxidative and metabolic stress). ⚡ 2. Metabolic Health Improves insulin sensitivity and glucose metabolism. Supports weight loss and fat oxidation. Reduces markers of metabolic syndrome and type 2 diabetes in animal models. 💪 3. Exercise & Performance Enhancement Enhances endurance and physical capacity. Protects muscles from exercise-induced stress. Mimics some effects of exercise even without activity ('exercise mimetic'). 🧬 4. Mitochondrial Health Promotes mitochondrial biogenesis. Helps maintain mitochondrial DNA integrity and function under stress. 🧠 5. Neuroprotection (early-stage research) May protect brain cells from oxidative and metabolic damage. MOTS-c (5mg) fast delivery in london

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ NAD+ (Nicotinamide adenine dinucleotide), in a 100mg dose from Peptide Science, is used for a variety of potential benefits related to cellular health and function. These include supporting energy production, DNA repair, and combating the effects of aging. NAD+ plays a crucial role in numerous cellular processes, making it a subject of interest for both its potential therapeutic applications and its role in healthy aging. Energy Production: NAD+ is essential for the cellular energy production process, particularly in the mitochondria. It acts as a coenzyme, facilitating the transfer of electrons in redox reactions, which are crucial for ATP (energy) production. DNA Repair: NAD+ is a substrate for enzymes called PARPs, which play a vital role in repairing DNA damage. Maintaining sufficient NAD+ levels can help ensure proper DNA repair and genomic stability. ✅ Primary Uses of NAD⁺ (100mg) Cellular Energy Production NAD⁺ is essential for mitochondrial function, helping convert nutrients into ATP (energy). Often used to combat fatigue or low energy levels. Healthy Aging & Longevity NAD⁺ levels decline with age. Supplementation may support DNA repair, cellular health, and overall longevity via sirtuin activation (especially SIRT1). Cognitive Function May enhance brain health, memory, and focus by supporting neuronal function and reducing oxidative stress. Metabolic Support Helps regulate metabolism, insulin sensitivity, and weight management. May support healthy blood sugar levels. Addiction & Withdrawal Support (High-dose clinical setting) NAD⁺ IV therapy is sometimes used in detox programs to ease withdrawal symptoms and improve mental clarity. 100 mg is a low dose; IV protocols often use much higher amounts. Skin and Anti-Aging Products Included in some topical formulations to promote skin cell repair and reduce signs of aging. Sirtuin Activation: NAD+ is also required by sirtuins, a class of proteins involved in gene regulation, cellular stress responses, and potentially, longevity. Anti-Aging: Because NAD+ is involved in so many fundamental cellular processes, its decline with age is linked to various age-related changes. Maintaining NAD+ levels through supplementation is being explored as a way to potentially mitigate some of these changes and promote healthy aging.

Tirzepatide (20mg) Peptide Science |USES|DOSES|SIDE EFFECT FAST DELIVERY TO UNITED KINGDOM Contact Us on telegram or WhatsApp +917887449821 +919168783773 +91 9529672584 +91 7499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://wa.me/c/917499402610 Tirzepatide (20mg) USES : -Tirzepatide injection is used to treat type 2 diabetes. It is used together with diet and exercise to help control your blood sugar. Tirzepatide is a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist. Tirzepatide is a next-generation medication that acts as a dual agonist of GLP-1 and GIP receptors. It is approved for medical use under the brand name Mounjaro and is also available from research peptide sources (often as a 20mg vial). Chronic Weight Management (Obesity/Overweight) Approved by the FDA in 2023 under the name Zepbound For adults with: BMI ≥30, or BMI ≥27 with weight-related conditions (e.g., hypertension, sleep apnea, dyslipidemia) Shown in clinical trials to result in >20% average body weight loss at higher doses Studying fat loss mechanisms Investigating insulin resistance Testing combination therapy potential with GLP-1 analogs Exploring impacts on metabolic syndrome, NAFLD, and cardiovascular biomarkers 💉 Dosing Guidance (Clinical Reference) Week Typical Dose Weeks 1–4 2.5 mg weekly Weeks 5–8 5 mg weekly Weeks 9+ Increase by 2.5 mg every 4 weeks up to 15 mg weekly (max dose for Mounjaro/Zepbound) FAST DELIVERY IN UNITED KINGDOM FROM SKYBLUE INTERNATIONAL

Retatrutide 16mg is being developed to target multiple metabolic conditions, with its primary uses in obesity management, type 2 diabetes, and fatty liver disease. Retatrutide is an investigational triple hormone receptor agonist (GLP-1, GIP, and glucagon receptors) Main Uses of Retatrutide 1. Obesity Treatment Primary target: Adults with obesity (BMI ≥30) or overweight (BMI ≥27) with a weight-related condition. Effectiveness: Up to 24.2% body weight loss at the highest tested dose (12 mg) over 48 weeks. Outperformed semaglutide (Wegovy) and tirzepatide (Zepbound) in trials. Mechanism: Appetite suppression Slowed gastric emptying Increased energy expenditure Type 2 Diabetes Management Improves blood glucose control by: Enhancing insulin sensitivity Increasing insulin secretion Reducing glucagon levels (in a glucose-dependent way) Massive reductions in liver fat (up to 82.4% in some patients) Helps improve: Liver enzyme profiles (ALT, AST) Hepatic insulin resistance SKYBLUE INTERNATIONAL is a trusted global pharmaceutical export company specializing in the export of high-quality medicines. With a strong commitment to healthcare excellence, we supply a wide range of branded and generic medicines to countries including the USA, UK, Australia, UAE, Canada, Singapore, and the Philippines. Our focus is on reliability, compliance, and timely delivery to meet the global demand for affordable and effective medical solutions. Medicine 💊 Retatrutide (16mg) BUY FROM SKYBLUE INTERNATIONAL Weight reduction Improved insulin sensitivity Hormonal balancing

CJC-1295 + Ipamorelin (5/5mg) PEPTIDE SCIENCE IS AVAILABLE IN INDIA CJC-1295 DAC, also known as DAC:GRF (short for drug affinity complex:growth hormone-releasing factor), is a synthetic analogue of growth hormone-releasing hormone (GHRH) (also known as growth hormone-releasing factor (GRF)) and a growth hormone secretagogue (GHS) which was developed by ConjuChem Biotechnologies.[1][2][3] It is a modified form of GHRH (1-29) with improved pharmacokinetics, especially in regard to half-life. 1. Primary Uses ✅ Muscle Growth & Performance Enhancement Boosts lean muscle mass by increasing protein synthesis. Speeds up recovery from workouts or injuries (tendons, ligaments). Popular among athletes, bodybuilders, and fitness enthusiasts. ✅ Fat Loss & Metabolism Enhances lipolysis (fat breakdown), especially stubborn belly fat. Improves insulin sensitivity (beneficial for metabolic health). Anti-Aging & Longevity Stimulates collagen production → Firmer skin, reduced wrinkles. Supports joint health → Reduces age-related stiffness/pain. May improve sleep quality & cognitive function (GH regulates brain health). ✅ Injury & Tissue Repair Accelerates healing of muscles, tendons, and cartilage. Used by athletes recovering from strains or surgeries. SKYBLUE INTERNATIONAL is a trusted global pharmaceutical export company specializing in the export of high-quality medicines. With a strong commitment to healthcare excellence, we supply a wide range of branded and generic medicines to countries including the USA, UK, Australia, UAE, Canada, Singapore, and the Philippines. Our focus is on reliability, compliance, and timely delivery to meet the global demand for affordable and effective medical solutions. Medicine WE EXPORT TO SINGAPORE WE EXPORT TO AUD WE EXPORT TO CAD WE EXPORT TO UK WE EXPORT TO UAE