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Generic Name Bremelanotide
1. Hypoactive Sexual Desire Disorder (HSDD) in Women
FDA-approved in 2019 under the brand Vyleesi for pre-menopausal women with generalized HSDD unrelated to other medical or psychological condition
Improves sexual desire, arousal, and reduces distress linked to low libido
2. Erectile Dysfunction (ED) in Men (Off‑Label)
PT‑141 initiates erections via central nervous system pathways, increasing sexual desire and erection quality—even in men unresponsive to PDE‑5 inhibitors
Demonstrated increased duration and rigidity of erections in trials
3. Sexual Arousal Support
Boosts libido in both genders, addresses low sexual drive and arousal disorders, potentially enhancing orgasm quality and reducing refractory time
Bremelanotide is a 7 amino acid peptide used to treat hypoactive sexual desire disorder in premenopausal women. Bremelanotide does not interact with alcohol. The mechanism by which bremelanotide's action on receptors translates to a clinical effect is still unknown.
Bremelanotide was first described in the literature in 2003 when it was known by the investigational code PT-141.1 Since then it was investigated for its place in treating sexual dysfunction in men and women but is now only indicated for women.1,2,5 Other drugs used to treat female sexual dysfunction include flibanserin, estrogen, ospemifene, and prasterone.
Bremelanotide was granted FDA approval
Bremelanotide is an agonist of many melanocortin receptors which in order of potency are MC1R, MC4R, MC3R, MC5R, and MC2R.5 The mechanism by which agonism of these receptors translates to an improvement in hypoactive sexual desire disorder is currently unknown, however MC4R receptors are present in many areas of the central nervous system. MC3R and MC4R are found in the hypothalamus and are involved in food intake and energy homeostasis.
Bremelanotide is a 7 amino acid and so its metabolism consists of multiple hydrolysis reactions.
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Erectile Dysfunction (ED) in men
– As a PDE‑5 inhibitor, sildenafil relaxes penile blood vessels to increase blood flow during sexual arousal, helping achieve and maintain erections.
Pulmonary Arterial Hypertension (PAH) (off-label)
– By dilating pulmonary blood vessels, it can improve exercise tolerance and lower pulmonary artery pressures.
Emerging Use
Female Sexual Arousal Disorder (FSAD)
– Often referred to as “Female Viagra,” Cenforce FM enhances genital blood flow in women, increasing arousal, lubrication, and sexual sensation.
Cenforce 100mg Tablet is a prescription medicine used to treat erectile dysfunction (impotence) in men. .
It works by increasing blood flow to the penis. This helps men to get or maintain an erection.
It belongs to a group of medicines known as phosphodiesterase type 5 (PDE 5) inhibitors.
Gonadorelin 10mg , Peptide USA FAST DELIVERY
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1. 🎯 Diagnostic Testing of the HPG Axis
Used to assess pituitary function by measuring LH/FSH response—helpful in diagnosing hypogonadism or pituitary disorders .
2. 👩🔬 Female Infertility & Ovulation Induction
Triggers ovulation in women with irregular periods
Widely used in IVF and ART, often combined with hCG, to improve ovarian response and implantation rates
3. 👨 Male Hypogonadism & Delayed Puberty
Stimulates testosterone and spermatogenesis in male hypogonadotropic hypogonadism and delayed puberty
Helps prevent testicular atrophy during TRT and promotes natural LH/FSH production
4. 🧬 Hormone-Sensitive Cancers (Experimental)
Explored in breast and prostate cancer to suppress estrogen/testosterone over long-term use .
5. 🦴 Bone, Muscle & Metabolic Health (Research)
Preliminary studies show benefits for bone density, muscle strength, mood, and metabolic function via hormone regulation .
6. 🧠 Neurological & Cognitive Research
Emerging research on GnRH analogues for potential applications in Alzheimer's disease and cognitive health
Diagnosing HPG axis function
Boosting fertility and managing reproductive disorders
Treating male hormonal deficiencies and puberty delay
Evaluating emerging roles in cancer, veterinary fertility, bone/muscle health, and neurology
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Semorelin (15mg) UK FAST DELIVERY
Sermorelin is used to diagnose and treat poor growth in children. It's also sometimes used off-label to treat hGH deficiency in adults. Some research has suggested that it can be beneficial in people with certain recurrent brain tumors. Children usually benefit the most from sermorelin.
Sermorelin is a peptide hormone that is structurally similar to growth hormone-releasing hormone (GHRH).
positive effects of sermorelin : Antidepressants like sertraline help to improve your mood so you feel better
Popular among aging men and women to mimic youthful GH secretion.
Administration: Nighttime injection to mimic natural GH pulses.
Does Tesamorelin burn fat?
Tesamorelin injection is not used to help with weight loss.
Who can't take sermorelin?
if you are pregnant, planning to become pregnant, or are breast-feeding.
Drug Name Sermorelin Acetate
Form Lyophilized powder (freeze-dried) for reconstitution
Reconstitution Solvent Bacteriostatic Water for Injection (BWFI) or Sterile Water for Injection
Dosing and Administration (Typical)
Dose: Varies by provider and goal, but commonly 0.2–0.5 mg/day, subcutaneously at bedtime.
15 mg vial: Typically used over a 30-day period after being reconstituted with bacteriostatic water.
Administration: Nighttime injection to mimic natural GH pulses.
Improved body composition (more lean mass, less fat)
Better sleep
Enhanced recovery and energy
Possible cognitive and mood improvements
CJC-1295 DAC (5mg) FAST DELIVERY TO AUSTRALIA
SKYBLUE INTERNATIONAL is a trusted global pharmaceutical export company specializing in the export of high-quality medicines. With a strong commitment to healthcare excellence, we supply a wide range of branded and generic medicines to countries including the USA, UK, Australia, UAE, Canada, Singapore, and the Philippines. Our focus is on reliability, compliance, and timely delivery to meet the global demand for affordable and effective medical solutions. Medicine 💊
USES : CJC-1295 DAC (Drug Affinity Complex) is a long-acting growth hormone-releasing hormone (GHRH) analog designed to elevate IGF-1 and growth hormone (GH) levels for days after a single injection. Below is a detailed breakdown of its primary applications, mechanisms, and protocols.
Fat Loss & Metabolism
Boosts lipolysis (fat breakdown), especially stubborn visceral fat.
Improves insulin sensitivity → Supports metabolic health.
Mechanism: Binds to GHRH receptors in the pituitary → sustained GH release (elevates IGF-1 for 5-7 days per dose).
Half-life: 6-8 days (due to DAC modification, which prevents rapid breakdown).
Key Difference vs. CJC-1295 (no DAC):
CJC-1295 DAC → Long-lasting effects (fewer injections needed).
Standard CJC-1295 → Shorter duration (requires daily dosing).
Standard Protocol (5mg Vial)
Reconstitution: Mix with 2mL bacteriostatic water (yields 2.5mg/mL).
Dosing:
Beginner: 1mg (0.4mL) 2x/week (e.g., Monday & Thursday).
Advanced: 2mg (0.8mL) 2x/week (for maximum IGF-1 elevation).
Cycle Length: 8-12 weeks (followed by a 4-week break).
✅ Best for:
Athletes wanting sustained muscle growth & recovery.
Men/women targeting fat loss + anti-aging benefits.
Those who prefer fewer injections (vs. daily peptides).
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Tesamorelin + CJC-1295 + Ipamorelin (6/3/3mg) FAST DELIVERY TO DOORSTEPS
CJC-1295 is an incredibly effective peptide which works by stimulating the release of your own body's growth hormones (which drop quickly after the age of 30). Research has shown that CJC-1295 can increase growth hormone levels by 200-1000% and the elevated growth hormone production continued for up to 6 days.
It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Powder for Solution.
Conclusion: Treatment with tesamorelin was generally well tolerated and resulted in sustained decreases in VAT and triglycerides over 52 weeks without aggravating glucose. Though effects on VAT are sustained during treatment for 52 weeks, these effects do not last beyond the duration of treatment.
Signs of high blood sugar like confusion, feeling sleepy, unusual thirst or hunger, passing urine more often, flushing, fast breathing, or breath that smells like fruit. A fast heartbeat. Dizziness or passing out. Flushing.
1. Primary Medical & Performance Uses
A. Fat Loss (Especially Visceral Fat)
✅ Tesamorelin (6mg):
FDA-approved for HIV lipodystrophy (reduces abdominal fat).
Targets stubborn belly fat even in non-HIV patients.
✅ CJC-1295 (3mg) + Ipamorelin (3mg):
Amplifies growth hormone (GH) pulses for enhanced fat metabolism.
Preserves muscle during calorie deficits.
B. Muscle Growth & Recovery
Boosts IGF-1 levels → Increases protein synthesis.
Accelerates repair of tendons/ligaments (ideal for athletes).
C. Anti-Aging & Longevity
Improves skin elasticity (collagen stimulation).
Enhances sleep quality (GH promotes deep sleep cycles).
May support cognitive function (neuroprotective effects).
D. Metabolic Health
Improves insulin sensitivity (beneficial for prediabetes/metabolic syndrome).
Lowers triglycerides (cardiovascular support).
2. Mechanism of Action
Peptide Target Effect
Tesamorelin GHRH Receptor (Pituitary) Stimulates GH release, specifically reduces visceral fat.
CJC-1295 GHRH Receptor (Pituitary) Long-acting GH release (elevates IGF-1 for days).
Ipamorelin Ghrelin Receptor Selective GH boost (no cortisol/prolactin spikes).
Synergy:
Tesamorelin targets fat stores, while CJC-1295 + Ipamorelin prolong GH benefits for muscle and recovery.
3. Dosage & Administration
Standard Protocol
Blend Ratio: 6mg Tesamorelin + 3mg CJC-1295 + 3mg Ipamorelin per vial.
Daily Dose:
Tesamorelin: 1–2mg/day (e.g., 1mg AM, 1mg PM).
CJC-1295 + Ipamorelin: 100–300mcg each, 1–2x/day (post-workout or bedtime).
Cycle Length: 8–12 weeks (followed by 4-week break).
Reconstitution
Mix with 2–3mL bacteriostatic water (for precise dosing).
Storage: Refrigerate after reconstitution (stable for 4–6 weeks).
4. Expected Results & Timeline
📌 Weeks 1–4:
Reduced bloating, improved sleep, increased energy.
📌 Weeks 4–8:
Visible fat loss (especially abdomen), faster workout recovery.
📌 Weeks 8–12:
Lean muscle definition, tighter skin, enhanced endurance.
(Optimal with strength training + low-sugar diet.)
Final Verdict
✅ Best for:
Men/women targeting stubborn belly fat.
Athletes wanting muscle preservation + recovery.
Anti-aging (skin, cognition, longevity).
Description
Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection.
This medicine is available only with your doctor's prescription.
This product is available in the following dosage forms:
Description
Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection.
This medicine is available only with your doctor's prescription.
This product is available in the following dosage forms:
Tesamorelin may sometimes be given at home to patients who do not need to be in a hospital or clinic. If you are using this medicine at home, your doctor or nurse will teach you how to prepare and inject the medicine. Be sure that you understand how to use the medicine.
Tesamorelin injection comes with a patient information leaflet and patient instructions. Read the instructions and make sure you understand:
How to prepare the injection.
Proper use of disposable syringes.
How to give the injection.
How long the injection is stable.
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Ipamorelin works by binding to IGF-1 receptors in the body and mimicking its effects on those receptors. This causes an increase in muscle mass and strength, as well as fat loss due to increased metabolism and lipolysis (the breakdown of fat).
Semorelin + Ipamorelin (5mg/5mg) – Key Uses, Benefits & Protocol
This growth hormone (GH)-stimulating peptide blend is used for anti-aging, fat loss, muscle growth, and recovery.
1. Primary Uses
A. Anti-Aging & Longevity
Boosts collagen → Improves skin elasticity, reduces wrinkles.
Enhances sleep quality → Deepens REM sleep for cellular repair.
Supports cognitive function → May improve memory/focus.
B. Fat Loss & Metabolism
Reduces stubborn fat (especially visceral/belly fat).
Improves insulin sensitivity → Helps with metabolic disorders.
C. Muscle Growth & Recovery
Increases lean muscle mass (without water retention).
Speeds up injury recovery (tendons, ligaments, joints).
D. Performance Enhancement (Athletes/Bodybuilders)
Enhances workout recovery → Less soreness, faster gains.
Preserves muscle during cutting phases.
2. How It Works
Sermorelin → Stimulates natural GH release from the pituitary.
Ipamorelin → A selective GH secretagogue (avoids cortisol/prolactin spikes).
Synergy: More sustained GH pulses than either peptide alone.
(Unlike synthetic HGH, this combo promotes natural, balanced GH secretion.)
3. Dosage & Administration
Standard Dose: 5mg Sermorelin + 5mg Ipamorelin per vial (mixed with bacteriostatic water).
Daily Injection:
100-300mcg each (e.g., 100mcg Sermorelin + 100mcg Ipamorelin).
Typically 1-2 injections/day (morning and/or before bed).
Cycle Length: 8-12 weeks (then take a 4-week break).
4. Expected Results & Timeline
📌 4-6 Weeks: Better sleep, increased energy, reduced body fat.
📌 8-12 Weeks: Visible muscle tone, tighter skin, faster recovery.
📌 3+ Months: Long-term anti-aging benefits (if cycled properly).
(Best paired with strength training + high-protein diet.)
7. Alternatives to Consider
Peptide Best For Pros Cons
Tesamorelin + Ipamorelin Fat loss (visceral) FDA-approved (for HIV lipodystrophy) Expensive
Final Verdict
✅ Best for:
Anti-aging (skin, cognition, longevity).
Athletes seeking muscle growth + recovery.
Men/women targeting stubborn fat.
. Detailed Benefits & Science
How it compares to HGH or other peptides (like CJC-1295).
Anti-aging mechanisms (collagen, cellular repair).
2. Cycle Recommendations
Optimal dosing (e.g., 100mcg vs. 300mcg per day).
How long to run it (8 vs. 12 weeks).
5. Success Stories/User Experiences
Real-world results for fat loss, muscle gain, or skin improvement.
Increased energy levels: sermorelin and ipamorelin help boost energy and stamina, allowing you to feel more active and engaged throughout the day. Improved sleep quality: By enhancing restorative sleep, sermorelin and ipamorelin can lead to better overall health and well-being.
Sermorelin is a peptide hormone that is structurally similar to growth hormone-releasing hormone (GHRH). It is typically used to treat growth hormone deficiency in children and adults. It can also be used for other conditions, such as improving wound healing, reducing fat mass, and increasing muscle mass.
Sermorelin and Ipamorelin peptides are often combined because they have synergistic properties. Research has proven them to help slow down the aging process, increase muscle mass, decrease fat mass, reduce inflammation, heal the gut and more.
How often should I take Sermorelin? A dosage of 0.2-0.3 mcg once daily at bedtime by subcutaneous injection is recommended.
Ipamorelin is a peptide that has been shown to increase growth hormone levels in humans by stimulating the hypothalamus, which is responsible for regulating the secretion of growth hormone. Ipamorelin works by binding to IGF-1 receptors in the body and mimicking its effects on those receptors. This causes an increase in muscle mass and strength, as well as fat loss due to increased metabolism and lipolysis (the breakdown of fat).
When Can I Expect To See Results?
While patients will notice some significant increases changes in the body after the first month, the full-benefits are usually fully noticed after three to six months of therapy.
Month 1
* Increased energy
* Improved stamina
* Deeper, more restful sleep
Month 2
* Improved skin, reduced wrinkles
* Stronger nails and hair
* Increased metabolism
Month 3
* Enhanced sex drive and performance
* Improved mental focus
* Improved joint health
Month 4
* Continued weight reduction
* Improved skin elasticity
* Increased lean muscle mass
Month 5
* Noticeably fuller and healthier hair
* Reduced appearance of wrinkles, better skin tone
* Continued reduction in belly fat
Month 6
* 5-10% reduction in body fat (without exercise/diet)
* 10% increase in lean muscle mass
* Improved vitality due to organ regrowth
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Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection.
Tesamorelin + Ipamorelin (6mg/2mg) Blend: Medical Uses & Applications
This peptide combination is primarily used for metabolic, anti-aging, and body composition benefits. Here’s a breakdown of its primary medical and off-label uses:
1. Approved Medical Use (FDA-Approved for HIV Lipodystrophy)
✅ Tesamorelin (6mg)
FDA-approved to treat HIV-associated lipodystrophy (excess belly fat caused by antiretroviral therapy).
Mechanism: Stimulates growth hormone (GH) release, reducing visceral fat.
2. Off-Label & Research-Based Uses
A. Fat Loss & Metabolic Health
Visceral fat reduction (even in non-HIV patients).
Improves insulin sensitivity (potential for metabolic syndrome/type 2 diabetes support).
B. Muscle Growth & Recovery
Ipamorelin (2mg) is a growth hormone secretagogue (GHS) that:
Boosts lean muscle mass.
Enhances post-workout recovery.
C. Anti-Aging & Longevity
Increases collagen production (improves skin elasticity).
May support cognitive function (GH plays a role in brain health).
D. Injury & Tissue Repair
Accelerates healing of tendons/ligaments (used by athletes).
3. Typical Treatment Protocol
Dosage:
Tesamorelin: 1-2mg/day (often 6mg total per week).
Ipamorelin: 200-300mcg/day (2mg total per week).
Administration: Subcutaneous injections (stomach or thigh).
Cycle Length: 8-12 weeks (with breaks to avoid GH desensitization).
4. Key Benefits vs. Other Peptides
Peptide Primary Use Pros Cons
Tesamorelin FDA-approved fat loss Targets stubborn belly fat Expensive, requires prescri
Final Verdict
This blend is best for:
✔ Men/women targeting stubborn fat (especially abdominal).
✔ Athletes seeking muscle recovery & anti-aging benefits.
✔ Those wanting a safer alternative to synthetic GH.
4. Typical Dosage & Protocol
Tesamorelin: 1-2mg/day (or 6mg/week).
Ipamorelin: 200-300mcg/day (or 2mg/week).
Administration: Subcutaneous injection (stomach/thigh).
Cycle Length: 8-12 weeks (followed by a break to avoid GH resistance).
3. How It Works
Tesamorelin → Stimulates pituitary GH release → Reduces visceral fat.
5. Expected Results & Timeline
📌 4-6 Weeks: Reduced belly fat, improved energy.
📌 8-12 Weeks: Visible muscle definition, better skin elasticity.
📌 Beyond 3 Months: Enhanced recovery, potential cognitive benefits.
5. Expected Results & Timeline
📌 4-6 Weeks: Reduced belly fat, improved energy.
📌 8-12 Weeks: Visible muscle definition, better skin elasticity.
📌 Beyond 3 Months: Enhanced recovery, potential cognitive benefits.
5. Expected Results & Timeline
📌 4-6 Weeks: Reduced belly fat, improved energy.
📌 8-12 Weeks: Visible muscle definition, better skin elasticity.
📌 Beyond 3 Months: Enhanced recovery, potential cognitive benefits.
(Best when combined with diet + exercise) .
Rare (serious):
Increased blood sugar (caution for diabetics).
Carpal tunnel syndrome (high doses).
Final Verdict
✅ Best for:
Men/women struggling with belly fat.
Athletes seeking muscle recovery + anti-aging.
Those wanting GH benefits without synthetic HGH risks.
❌ Not for: Quick fixes – requires consistent use for 2-3 months
Tesamorelin, known for reducing abdominal fat in HIV patients with lipodystrophy, together with Ipamorelin, a growth hormone-releasing peptide, can enhance overall body composition improvements. Furthermore, both substances may work synergistically to boost muscle growth, fat loss, recovery, and anti-aging effects, maximizing the benefits of each peptide when used in tandem.
Before taking this medicine
You should not use tesamorelin if you are allergic to it, or if you have:
cancer;
a pituitary gland disorder;
a history of pituitary gland tumor or surgery;
a history of head injury or radiation treatment; or
if you are pregnant.
To make sure you can safely take tesamorelin, tell your doctor if you have any of these other conditions:
a history of cancer or any tumor (either benign or malignant);
heart disease, high blood pressure;
kidney disease;
diabetes, eye problems caused by diabetes;
epilepsy
asthma;
migraine headaches;
adrenal gland disorder;
if you have ever had open heart surgery; or
if you have any major illness, a recent trauma, or a medical emergency.
FDA pregnancy category X. This medication can harm an unborn baby or cause birth defects. Do not use tesamorelin if you are pregnant. Tell your doctor right away if you become pregnant during treatment.
Women with HIV or AIDS should not breastfeed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
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REESHAPE 60 MG
Reeshape 60 Capsule is a medicine used in the treatment of obesity. It helps the body in blocking the absorption of fats from the small intestines and stomach. This way it can help reduce calorie intake and weight loss over time.
Reeshape 60 Capsule is geenrally taken orally 3 times daily, during (or up to 1 hour after) each main meal containing fat. It can also be taken up to 2 hours after midmeal. It works best when it is used along with regular physical activity and a healthy diet. It should not be taken for a long term unless your doctor tells you to do so. For better efficacy of the medicine, fat-rich foods should be avoided along with the medicine.
Some of the common side effects of Reeshape 60 Capsule include the presence of fat in the stool, abdominal pain, and diarrhea. If any of the side effects bother you, tell your doctor without delay. They may be able to help you by adjusting your dose or prescribe you an alternate medicine.
Pregnant and breastfeeding women must take this medicine only with a valid prescription. Inform your doctor before taking the medicine if you have any other medical conditions or are taking any other medications. This medicine should not be considered as a long-term treatment unless you are prescribed by your doctor.
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