The first 29 amino acids of GHRH were discovered to be as equally potent as its full 44 amino acid structure[1][2] This fragment became known as GRF (1-29). However, due to a rapid metabolic clearance analogues of GRF (1-29) were synthesized to enhance the biological activity and reduce the rapidity of metabolic clearance. These analogues were primarily created by substituting amino acids within the peptide structure for amino acids more resistant to enzymatic cleavage. One early analogue substituted the amino acid L-alanine (abbreviated as Ala or A) at the 2nd position of the peptide structure for its optical isomer (mirror image), D-alanine (abbreviated as D-Ala). This substitution resulted in a peptide bond between D-Ala and the 3rd amino acid in the structure aspartic acid (Asp) more able to resist rapid cleavage by the enzyme dipeptidyl peptidase-4, a cleavage which had previously led to an inactive peptide fragment.[3][4] This successful modification prompted the further creation of analogues with additional amino acid substitutions. Ipamorelin: A selective growth hormone secretagogue, Ipamorelin stimulates the release of GH by mimicking ghrelin's action on the ghrelin receptor. It is known for its specificity and minimal side effects compared to other GH-releasing peptides. Mod GRF 1-29 (CJC-1295 without DAC): This is a modified version of the first 29 amino acids of growth hormone-releasing hormone (GHRH). The modifications extend its half-life and enhance its ability to stimulate the pituitary gland to release GH. It is often used in research to study GH secretion patterns and related metabolic effects. ⚖️ Dosage and Composition The 5/5 mg blend indicates that each vial contains 5 mg of Mod GRF 1-29 and 5 mg of Ipamorelin, totaling 10 mg per vial. This combination is designed to provide a balanced stimulation of GH release, potentially offering synergistic effects when used in research protocols. 🔬 Research Applications In scientific studies, this peptide blend is utilized to: Study Growth Hormone Dynamics: Investigating the patterns and regulation of GH secretion. Metabolic Research: Understanding the role of GH in metabolism, including fat metabolism and muscle growth. Aging and Longevity Studies: Exploring the effects of GH on aging processes and potential therapeutic applications. Sleep and Recovery Research: Examining how GH influences sleep patterns and recovery processes. ⚠️ Important Considerations Research Use Only: These peptides are intended strictly for laboratory research and are not approved for human or veterinary use. Legal Status: The legality of purchasing and possessing these peptides varies by country and jurisdiction. It's essential to consult local regulations before acquiring them. Storage and Handling: Proper storage conditions are crucial to maintain peptide stability. Typically, lyophilized peptides should be stored at -20°C or colder and protected from light. Reconstitution should be done with appropriate solvents, and solutions should be stored at 4°C and used within a specified timeframe. Mod GRF 1-29 + Ipamorelin (5/5 mg) is primarily used in scientific research and clinical studies to investigate its effects on human growth hormone (GH) release and related metabolic functions. It is not FDA-approved for general medical use, but here are the commonly researched uses and potential applications: Stimulation of Growth Hormone (GH) Release Both peptides work synergistically to enhance the natural pulsatile release of GH from the pituitary gland. Mod GRF 1-29 initiates GH release, while Ipamorelin amplifies it by mimicking ghrelin. Anti-Aging Studies GH has regenerative effects on tissues, so researchers study this combo to explore its potential for: Improving skin elasticity Increasing energy levels Enhancing sleep quality Muscle Growth and Recovery (in studies) GH can help stimulate muscle protein synthesis and recovery. This combo is sometimes researched for its effects on lean muscle mass and exercise recovery. Fat Loss & Metabolic Support GH mobilizes stored fat, making this blend of interest in obesity and metabolic syndrome research. May support lipolysis (fat breakdown) in clinical models. Bone Density Studies GH supports bone mineralization. This combo is explored for potential applications in osteopenia/osteoporosis research. Sleep Improvement GH release is tied to deep sleep stages; researchers observe whether this combo improves sleep architecture and REM sleep. Modified GRF (1-29) acts to increase growth hormone production and release by binding to the growth-hormone-releasing hormone receptor (GHRHR) on cells in the anterior pituitary.

P21 (P021) 5mg Peptide mechanism of Action Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+91 9529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Product Name P21 Peptide (a.k.a. P021) Common Dosage Form 5mg lyophilized powder per vial Type Synthetic neurotrophic peptide Molecular Formula Varies (not publicly disclosed due to proprietary status) Molecular Weight ~1,200–1,800 Da (estimated, depending on modification) CAS Number Not officially registered (research compound) Sequence Proprietary — derived from a CNTF (Ciliary Neurotrophic Factor) analog Purity ≥ 98% (HPLC tested) Peptide Content ≥ 90% Appearance White to off-white lyophilized powder 🧠 Primary Uses of P21 (5mg): 1. Cognitive Enhancement (Nootropic Use) Improves memory, learning speed, and mental clarity Supports executive function and attention span Often used by individuals looking to combat brain fog or age-related decline 2. Neurogenesis & Brain Repair Promotes growth of new neurons (neurogenesis) and synaptic plasticity May help in recovery from brain injury, stroke, or trauma 3. Neuroprotection Reduces oxidative stress, inflammation, and cell death in brain tissues Protects neurons from degenerative conditions like Alzheimer’s or Parkinson’s (in animal models) 4. Mood and Motivation May increase dopaminergic activity, supporting motivation, drive, and emotional balance Anecdotal reports suggest reduced anxiety and depressive symptoms 5. Combating Age-Related Cognitive Decline Potential anti-aging effects on brain structure and function May increase levels of BDNF (Brain-Derived Neurotrophic Factor) ⚙️ Mechanism of Action Mimics and enhances CNTF (Ciliary Neurotrophic Factor) signaling Promotes neural stem cell differentiation Boosts BDNF and NGF (nerve growth factor) activity Inhibits pathways involved in neuronal apoptosis (cell death) buy from us at best price

GHK-CU 50mg, Peptide Cape Coral FAST DELIVERY Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ GHK-Cu (Copper Peptide, 50mg) is a well-known regenerative peptide complex made of glycyl-L-histidyl-L-lysine bound to a copper ion. It naturally occurs in the human body and plays a key role in tissue repair, skin regeneration, inflammation control, and hair growth. When provided in 50mg lyophilized vials, GHK-Cu is typically used for cosmetic and therapeutic purposes — both topical and injectable (research use only). 💎 1. Skin Regeneration & Anti-Aging Stimulates collagen and elastin production Reduces fine lines, wrinkles, and hyperpigmentation Increases skin firmness and elasticity Promotes wound healing and reduces scarring 💇 2. Hair Growth Stimulation Increases size of hair follicles and improves hair thickness Shown to regrow hair in androgenetic alopecia (male/female pattern baldness) Often used in microneedling treatments or topical serums 🧫 3. Tissue Repair & Wound Healing Enhances the body's healing response at cellular level Promotes angiogenesis (new blood vessel formation) Reduces inflammation and oxidative stress 🧠 4. Anti-Inflammatory & Antioxidant Effects Modulates gene expression to suppress pro-inflammatory pathways Helps protect against oxidative damage in tissues and organs 🧪 5. Stem Cell Activation Enhances activity of skin and bone marrow stem cells Supports regeneration in injured or aging tissues BUY IT NOW FROM US BUY GHK-CU 50mg IN Pembroke Pines BUY GHK-CU 50mg IN Pembroke Pines

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+91 9529672584‬ ‪+91 7499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ BPC-157 (10mg) BPC 157, a pentadecapeptide derived from human gastric juice, has been demonstrated to promote the healing of different tissues, including skin, muscle, bone, ligament and tendon in many animal studies. However, the underlying mechanism has not been fully clarified. BPC-157 (10 mg) is a higher-dose vial of the Body Protective Compound-157, used for the same purposes as the 5 mg version—but typically more convenient for longer cycles, higher doses, or multi-site injuries. 🦴 1. Muscle, Tendon, Ligament, and Joint Repair Speeds healing from injuries: strains, tears, sprains, surgeries Often used by athletes recovering from rotator cuff tears, knee injuries, or Achilles tendonitis Can be injected near the injury or taken systemically 🧠 2. Nerve Healing & Neuroprotection Supports regeneration of damaged peripheral nerves May assist in recovery from nerve crush injuries or neuropathy Early animal studies show neuroprotective effects in traumatic brain injury models 🧪 3. Gastrointestinal Repair One of the most effective peptides for gut healing Used in: Leaky gut IBS / IBD (Crohn’s, ulcerative colitis) Gastric ulcers NSAID-induced intestinal damage 🧘‍♂️ 4. Anti-Inflammatory Effects Reduces chronic systemic inflammation Supports reduction of oxidative stress Can improve pain, swelling, and mobility in injured or inflamed tissues 🔁 5. Wound Healing & Skin Regeneration Applied (sometimes topically or injected near wound) to accelerate healing of: Cuts and abrasions Post-surgical wounds Burns 🏋️‍♂️ 6. Athletic Recovery & Performance Used in biohacking and performance enhancement protocols Shortens recovery time between workouts Helps prevent overuse injuries ⚙️ Why Use a 10 mg Vial? More convenient for: Longer treatment cycles (2–6 weeks) Larger body weight or higher dosing needs Multiple injury sites (e.g., knee + shoulder) Reduces frequency of reconstitution BPC-157 (10mg) IS AVAILABLE

Contact Us on telegram or WhatsApp +917887449821‬ +919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ MOTS-c (5mg) :- MOTS-c (5mg), a mitochondrial-derived peptide, is being investigated for its potential to treat metabolic disorders, improve muscle function, and promote healthy aging. It's believed to play a role in regulating energy metabolism, insulin resistance, and the inflammatory response. While research is ongoing, MOTS-c is being explored as a potential therapeutic strategy for conditions like obesity, age-related diseases, and even osteoporosis. MOTS-c stands for 'Mitochondrial Open Reading Frame of the 12S rRNA-c'. It is a 16-amino acid peptide that acts like a hormone, influencing metabolism, stress response, and cellular energy production. Unlike other peptides, it originates from mitochondrial DNA, not nuclear DNA. Exercise and Aging: MOTS-c can enhance exercise endurance and potentially counteract age-related muscle decline Bone Health: Osteoporosis: MOTS-c has been shown to inhibit osteoclast activity and reduce bone loss, suggesting a potential role in preventing and treating osteoporosis. Other Potential Benefits: Anti-inflammatory Effects: MOTS-c may help regulate the inflammatory response, which is implicated in various diseases. Brain Health: Research indicates MOTS-c may improve cognitive function and memory. Cardiovascular Health: MOTS-c has been linked to improved heart function and blood vessel health. 🧠 1. Anti-Aging & Longevity Increases mitochondrial efficiency. Activates AMPK (AMP-activated protein kinase), a key longevity pathway. Promotes cellular stress resistance (e.g., oxidative and metabolic stress). ⚡ 2. Metabolic Health Improves insulin sensitivity and glucose metabolism. Supports weight loss and fat oxidation. Reduces markers of metabolic syndrome and type 2 diabetes in animal models. 💪 3. Exercise & Performance Enhancement Enhances endurance and physical capacity. Protects muscles from exercise-induced stress. Mimics some effects of exercise even without activity ('exercise mimetic'). 🧬 4. Mitochondrial Health Promotes mitochondrial biogenesis. Helps maintain mitochondrial DNA integrity and function under stress. 🧠 5. Neuroprotection (early-stage research) May protect brain cells from oxidative and metabolic damage. MOTS-c (5mg) fast delivery in london

Semorelin (15mg) UK FAST DELIVERY Sermorelin is used to diagnose and treat poor growth in children. It's also sometimes used off-label to treat hGH deficiency in adults. Some research has suggested that it can be beneficial in people with certain recurrent brain tumors. Children usually benefit the most from sermorelin. Sermorelin is a peptide hormone that is structurally similar to growth hormone-releasing hormone (GHRH). positive effects of sermorelin : Antidepressants like sertraline help to improve your mood so you feel better Popular among aging men and women to mimic youthful GH secretion. Administration: Nighttime injection to mimic natural GH pulses. Does Tesamorelin burn fat? Tesamorelin injection is not used to help with weight loss. Who can't take sermorelin? if you are pregnant, planning to become pregnant, or are breast-feeding. Drug Name Sermorelin Acetate Form Lyophilized powder (freeze-dried) for reconstitution Reconstitution Solvent Bacteriostatic Water for Injection (BWFI) or Sterile Water for Injection Dosing and Administration (Typical) Dose: Varies by provider and goal, but commonly 0.2–0.5 mg/day, subcutaneously at bedtime. 15 mg vial: Typically used over a 30-day period after being reconstituted with bacteriostatic water. Administration: Nighttime injection to mimic natural GH pulses. Improved body composition (more lean mass, less fat) Better sleep Enhanced recovery and energy Possible cognitive and mood improvements

CJC-1295 DAC (5mg) FAST DELIVERY TO AUSTRALIA SKYBLUE INTERNATIONAL is a trusted global pharmaceutical export company specializing in the export of high-quality medicines. With a strong commitment to healthcare excellence, we supply a wide range of branded and generic medicines to countries including the USA, UK, Australia, UAE, Canada, Singapore, and the Philippines. Our focus is on reliability, compliance, and timely delivery to meet the global demand for affordable and effective medical solutions. Medicine 💊 USES : CJC-1295 DAC (Drug Affinity Complex) is a long-acting growth hormone-releasing hormone (GHRH) analog designed to elevate IGF-1 and growth hormone (GH) levels for days after a single injection. Below is a detailed breakdown of its primary applications, mechanisms, and protocols. Fat Loss & Metabolism Boosts lipolysis (fat breakdown), especially stubborn visceral fat. Improves insulin sensitivity → Supports metabolic health. Mechanism: Binds to GHRH receptors in the pituitary → sustained GH release (elevates IGF-1 for 5-7 days per dose). Half-life: 6-8 days (due to DAC modification, which prevents rapid breakdown). Key Difference vs. CJC-1295 (no DAC): CJC-1295 DAC → Long-lasting effects (fewer injections needed). Standard CJC-1295 → Shorter duration (requires daily dosing). Standard Protocol (5mg Vial) Reconstitution: Mix with 2mL bacteriostatic water (yields 2.5mg/mL). Dosing: Beginner: 1mg (0.4mL) 2x/week (e.g., Monday & Thursday). Advanced: 2mg (0.8mL) 2x/week (for maximum IGF-1 elevation). Cycle Length: 8-12 weeks (followed by a 4-week break). ✅ Best for: Athletes wanting sustained muscle growth & recovery. Men/women targeting fat loss + anti-aging benefits. Those who prefer fewer injections (vs. daily peptides). WE EXPORT IN UK WE EXPORT IN SINGAPORE WE EXPORT IN DUBAI WE EXPORT IN JAPAN WE EXPORT IN CANADA

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Ipamorelin works by binding to IGF-1 receptors in the body and mimicking its effects on those receptors. This causes an increase in muscle mass and strength, as well as fat loss due to increased metabolism and lipolysis (the breakdown of fat). Semorelin + Ipamorelin (5mg/5mg) – Key Uses, Benefits & Protocol This growth hormone (GH)-stimulating peptide blend is used for anti-aging, fat loss, muscle growth, and recovery. 1. Primary Uses A. Anti-Aging & Longevity Boosts collagen → Improves skin elasticity, reduces wrinkles. Enhances sleep quality → Deepens REM sleep for cellular repair. Supports cognitive function → May improve memory/focus. B. Fat Loss & Metabolism Reduces stubborn fat (especially visceral/belly fat). Improves insulin sensitivity → Helps with metabolic disorders. C. Muscle Growth & Recovery Increases lean muscle mass (without water retention). Speeds up injury recovery (tendons, ligaments, joints). D. Performance Enhancement (Athletes/Bodybuilders) Enhances workout recovery → Less soreness, faster gains. Preserves muscle during cutting phases. 2. How It Works Sermorelin → Stimulates natural GH release from the pituitary. Ipamorelin → A selective GH secretagogue (avoids cortisol/prolactin spikes). Synergy: More sustained GH pulses than either peptide alone. (Unlike synthetic HGH, this combo promotes natural, balanced GH secretion.) 3. Dosage & Administration Standard Dose: 5mg Sermorelin + 5mg Ipamorelin per vial (mixed with bacteriostatic water). Daily Injection: 100-300mcg each (e.g., 100mcg Sermorelin + 100mcg Ipamorelin). Typically 1-2 injections/day (morning and/or before bed). Cycle Length: 8-12 weeks (then take a 4-week break). 4. Expected Results & Timeline 📌 4-6 Weeks: Better sleep, increased energy, reduced body fat. 📌 8-12 Weeks: Visible muscle tone, tighter skin, faster recovery. 📌 3+ Months: Long-term anti-aging benefits (if cycled properly). (Best paired with strength training + high-protein diet.) 7. Alternatives to Consider Peptide Best For Pros Cons Tesamorelin + Ipamorelin Fat loss (visceral) FDA-approved (for HIV lipodystrophy) Expensive Final Verdict ✅ Best for: Anti-aging (skin, cognition, longevity). Athletes seeking muscle growth + recovery. Men/women targeting stubborn fat. . Detailed Benefits & Science How it compares to HGH or other peptides (like CJC-1295). Anti-aging mechanisms (collagen, cellular repair). 2. Cycle Recommendations Optimal dosing (e.g., 100mcg vs. 300mcg per day). How long to run it (8 vs. 12 weeks). 5. Success Stories/User Experiences Real-world results for fat loss, muscle gain, or skin improvement. Increased energy levels: sermorelin and ipamorelin help boost energy and stamina, allowing you to feel more active and engaged throughout the day. Improved sleep quality: By enhancing restorative sleep, sermorelin and ipamorelin can lead to better overall health and well-being. Sermorelin is a peptide hormone that is structurally similar to growth hormone-releasing hormone (GHRH). It is typically used to treat growth hormone deficiency in children and adults. It can also be used for other conditions, such as improving wound healing, reducing fat mass, and increasing muscle mass. Sermorelin and Ipamorelin peptides are often combined because they have synergistic properties. Research has proven them to help slow down the aging process, increase muscle mass, decrease fat mass, reduce inflammation, heal the gut and more. How often should I take Sermorelin? A dosage of 0.2-0.3 mcg once daily at bedtime by subcutaneous injection is recommended. Ipamorelin is a peptide that has been shown to increase growth hormone levels in humans by stimulating the hypothalamus, which is responsible for regulating the secretion of growth hormone. Ipamorelin works by binding to IGF-1 receptors in the body and mimicking its effects on those receptors. This causes an increase in muscle mass and strength, as well as fat loss due to increased metabolism and lipolysis (the breakdown of fat). When Can I Expect To See Results? While patients will notice some significant increases changes in the body after the first month, the full-benefits are usually fully noticed after three to six months of therapy. Month 1 * Increased energy * Improved stamina * Deeper, more restful sleep Month 2 * Improved skin, reduced wrinkles * Stronger nails and hair * Increased metabolism Month 3 * Enhanced sex drive and performance * Improved mental focus * Improved joint health Month 4 * Continued weight reduction * Improved skin elasticity * Increased lean muscle mass Month 5 * Noticeably fuller and healthier hair * Reduced appearance of wrinkles, better skin tone * Continued reduction in belly fat Month 6 * 5-10% reduction in body fat (without exercise/diet) * 10% increase in lean muscle mass * Improved vitality due to organ regrowth WE EXPORT TO USA WE EXPORT TO UK WE EXORT TO CANADA WE EXPORT TO SINGAPORE WE EXPORT