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1. 🎯 Diagnostic Testing of the HPG Axis
Used to assess pituitary function by measuring LH/FSH response—helpful in diagnosing hypogonadism or pituitary disorders .
2. 👩🔬 Female Infertility & Ovulation Induction
Triggers ovulation in women with irregular periods
Widely used in IVF and ART, often combined with hCG, to improve ovarian response and implantation rates
3. 👨 Male Hypogonadism & Delayed Puberty
Stimulates testosterone and spermatogenesis in male hypogonadotropic hypogonadism and delayed puberty
Helps prevent testicular atrophy during TRT and promotes natural LH/FSH production
4. 🧬 Hormone-Sensitive Cancers (Experimental)
Explored in breast and prostate cancer to suppress estrogen/testosterone over long-term use .
5. 🦴 Bone, Muscle & Metabolic Health (Research)
Preliminary studies show benefits for bone density, muscle strength, mood, and metabolic function via hormone regulation .
6. 🧠 Neurological & Cognitive Research
Emerging research on GnRH analogues for potential applications in Alzheimer's disease and cognitive health
Diagnosing HPG axis function
Boosting fertility and managing reproductive disorders
Treating male hormonal deficiencies and puberty delay
Evaluating emerging roles in cancer, veterinary fertility, bone/muscle health, and neurology
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FoxO4-DRI = A powerful senolytic research peptide
Acts via FoxO4-p53 disruption, promoting senescent cell apoptosis
Highly promising in aging, neurodegeneration, and regenerative biology fields
🔬 1. Anti-Aging & Longevity Research
Clears senescent cells, which accumulate with age and cause inflammation and tissue dysfunction.
By removing these cells, FoxO4-DRI may slow biological aging and restore tissue function (based on animal studies).
Shown to extend healthspan (not necessarily lifespan) in mice.
🧪 2. Cellular Rejuvenation
Helps promote tissue regeneration and stem cell activation.
May reverse signs of aging at the cellular level, especially in tissues like muscles, kidneys, and the brain.
🧠 3. Cognitive Health
Studies in mice showed memory improvement and neural rejuvenation in aged animals after FoxO4-DRI treatment.
Potential use in research for neurodegenerative diseases like Alzheimer’s or age-related cognitive decline.
🩺 4. Senolytic Therapy Research
Works by disrupting the interaction between FoxO4 and p53, which causes senescent cells to undergo apoptosis (programmed cell death).
May be combined in research with other senolytics like Dasatinib and Quercetin.
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MOTS-c (5mg) :- MOTS-c (5mg), a mitochondrial-derived peptide, is being investigated for its potential to treat metabolic disorders, improve muscle function, and promote healthy aging. It's believed to play a role in regulating energy metabolism, insulin resistance, and the inflammatory response. While research is ongoing, MOTS-c is being explored as a potential therapeutic strategy for conditions like obesity, age-related diseases, and even osteoporosis.
MOTS-c stands for 'Mitochondrial Open Reading Frame of the 12S rRNA-c'.
It is a 16-amino acid peptide that acts like a hormone, influencing metabolism, stress response, and cellular energy production.
Unlike other peptides, it originates from mitochondrial DNA, not nuclear DNA.
Exercise and Aging:
MOTS-c can enhance exercise endurance and potentially counteract age-related muscle decline
Bone Health:
Osteoporosis: MOTS-c has been shown to inhibit osteoclast activity and reduce bone loss, suggesting a potential role in preventing and treating osteoporosis.
Other Potential Benefits:
Anti-inflammatory Effects: MOTS-c may help regulate the inflammatory response, which is implicated in various diseases.
Brain Health: Research indicates MOTS-c may improve cognitive function and memory.
Cardiovascular Health: MOTS-c has been linked to improved heart function and blood vessel health.
🧠 1. Anti-Aging & Longevity
Increases mitochondrial efficiency.
Activates AMPK (AMP-activated protein kinase), a key longevity pathway.
Promotes cellular stress resistance (e.g., oxidative and metabolic stress).
⚡ 2. Metabolic Health
Improves insulin sensitivity and glucose metabolism.
Supports weight loss and fat oxidation.
Reduces markers of metabolic syndrome and type 2 diabetes in animal models.
💪 3. Exercise & Performance Enhancement
Enhances endurance and physical capacity.
Protects muscles from exercise-induced stress.
Mimics some effects of exercise even without activity ('exercise mimetic').
🧬 4. Mitochondrial Health
Promotes mitochondrial biogenesis.
Helps maintain mitochondrial DNA integrity and function under stress.
🧠 5. Neuroprotection (early-stage research)
May protect brain cells from oxidative and metabolic damage.
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CJC-1295 + Ipamorelin (5/5mg) PEPTIDE SCIENCE IS AVAILABLE IN INDIA
CJC-1295 DAC, also known as DAC:GRF (short for drug affinity complex:growth hormone-releasing factor), is a synthetic analogue of growth hormone-releasing hormone (GHRH) (also known as growth hormone-releasing factor (GRF)) and a growth hormone secretagogue (GHS) which was developed by ConjuChem Biotechnologies.[1][2][3] It is a modified form of GHRH (1-29) with improved pharmacokinetics, especially in regard to half-life.
1. Primary Uses
✅ Muscle Growth & Performance Enhancement
Boosts lean muscle mass by increasing protein synthesis.
Speeds up recovery from workouts or injuries (tendons, ligaments).
Popular among athletes, bodybuilders, and fitness enthusiasts.
✅ Fat Loss & Metabolism
Enhances lipolysis (fat breakdown), especially stubborn belly fat.
Improves insulin sensitivity (beneficial for metabolic health).
Anti-Aging & Longevity
Stimulates collagen production → Firmer skin, reduced wrinkles.
Supports joint health → Reduces age-related stiffness/pain.
May improve sleep quality & cognitive function (GH regulates brain health).
✅ Injury & Tissue Repair
Accelerates healing of muscles, tendons, and cartilage.
Used by athletes recovering from strains or surgeries.
SKYBLUE INTERNATIONAL is a trusted global pharmaceutical export company specializing in the export of high-quality medicines. With a strong commitment to healthcare excellence, we supply a wide range of branded and generic medicines to countries including the USA, UK, Australia, UAE, Canada, Singapore, and the Philippines. Our focus is on reliability, compliance, and timely delivery to meet the global demand for affordable and effective medical solutions. Medicine
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Skyblue International leading exporter of Ledifos Ledipasvir (90mg) + Sofosbuvir (400mg) USA FAST DELIVERY
Skyblue International leading exporter of Ledifos Ledipasvir (90mg) + Sofosbuvir (400mg)WE EXPORT IN, KioBedok,Bishan,Bukit Batok,Bukit Merah, Bukit Panjang,Choa Chu Kang, Clementi,Geylang,Hougang, Jurong East, Jurong West, Kallang, Marine Parade, Queenstown ,Sengkang, Simei ,Tampines,. Toa Payoh,Woodlands, Yishun.
Use for:- To treat chronic Hepatitis C
PRICE - $98
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Skyblue International leading exporter of Sofosbuvir 400mg/Ledipasvir 90mg tablets are a combination medication used to treat chronic hepatitis C virus (HCV) infection. This combination inhibits HCV replication, offering high cure rates across multiple genotypes. It's prescribed for adults, helping to improve liver function and reduce the risk of complications like cirrhosis and liver failure.
Uses: Ledifos 90mg/400mg Tablet is a combination of two antiviral medicines. This prescription medicine is used in the treatment of chronic hepatitis C virus (HCV) infection. It fights against the viruses to resolve the infection. Ledifos 90mg/400mg Tablet should be taken in the prescribed dose and duration.
DOSES:- For hepatitis C virus infection: Adults—1 tablet once a day, taken for 12 or 24 weeks.
Menopace capsules are used to manage the symptoms of menopause, including hot flashes, night sweats, and mood swings.
What is the use of benefit Tablet?
Benefit Tablet | Uses, Side Effects, Price | Apollo Pharmacy
Benefit tablets pack a punch with essential vitamins and minerals, including Zinc (immunity), Chromium (blood sugar support), and Selenium (cell health). This potent combo can address deficiencies and potentially boost your energy levels for overall well-being.
What is the success rate of ledipasvir sofosbuvir?
The rates of sustained virologic response were 99% (95% confidence interval [CI], 96 to 100) in the group that received 12 weeks of ledipasvir–sofosbuvir.
Ledipasvir (90mg) + Sofosbuvir (400mg) Ledifos USA FAST DELIVERY| Doses, In India, large demand for them and the high cost of bringing them to market. Developing a new drug, testing it in clinical trials, and marketing it can cost pharmaceutical companies nearly $900 million.
What is the first line treatment for HCV?
Hepatitis C is treated using direct-acting antiviral (DAA) tablets.
How long is the treatment for sofosbuvir and ledipasvir?
Ledipasvir/sofosbuvir (LDV/SOF) combination is administered for 12 to 24 weeks
What are the 5 stages of menopause?
What Are the 5 Stages of Menopause? [Understand the Process]
While every woman's experience is unique, knowing what to expect during each phase can help you prepare for and manage the changes ahead.
What is Menopause? ...
Stage 1: Perimenopause. ...
Stage 2: Early Menopause Transition. ...
Stage 3: Late Menopause Transition. ...
Stage 4: Menopause. ...
Stage 5: Postmenopause.
Can I increase estrogen levels naturally?
How to increase estrogen naturally | UCLA Health
To increase your estrogen levels, consider adding: Boron, a mineral that helps your body absorb testosterone and estrogen. Vitamin B, which helps your body create and use estrogen. Vitamin D, which functions as a hormone in the body and helps with estrogen production
Ledipasvir (90mg) + Sofosbuvir (400mg) Tablets are used for a wide range of purposes, including media consumption, productivity, and education.
Tesamorelin + CJC-1295 + Ipamorelin (6/3/3mg) FAST DELIVERY TO DOORSTEPS
CJC-1295 is an incredibly effective peptide which works by stimulating the release of your own body's growth hormones (which drop quickly after the age of 30). Research has shown that CJC-1295 can increase growth hormone levels by 200-1000% and the elevated growth hormone production continued for up to 6 days.
It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Powder for Solution.
Conclusion: Treatment with tesamorelin was generally well tolerated and resulted in sustained decreases in VAT and triglycerides over 52 weeks without aggravating glucose. Though effects on VAT are sustained during treatment for 52 weeks, these effects do not last beyond the duration of treatment.
Signs of high blood sugar like confusion, feeling sleepy, unusual thirst or hunger, passing urine more often, flushing, fast breathing, or breath that smells like fruit. A fast heartbeat. Dizziness or passing out. Flushing.
1. Primary Medical & Performance Uses
A. Fat Loss (Especially Visceral Fat)
✅ Tesamorelin (6mg):
FDA-approved for HIV lipodystrophy (reduces abdominal fat).
Targets stubborn belly fat even in non-HIV patients.
✅ CJC-1295 (3mg) + Ipamorelin (3mg):
Amplifies growth hormone (GH) pulses for enhanced fat metabolism.
Preserves muscle during calorie deficits.
B. Muscle Growth & Recovery
Boosts IGF-1 levels → Increases protein synthesis.
Accelerates repair of tendons/ligaments (ideal for athletes).
C. Anti-Aging & Longevity
Improves skin elasticity (collagen stimulation).
Enhances sleep quality (GH promotes deep sleep cycles).
May support cognitive function (neuroprotective effects).
D. Metabolic Health
Improves insulin sensitivity (beneficial for prediabetes/metabolic syndrome).
Lowers triglycerides (cardiovascular support).
2. Mechanism of Action
Peptide Target Effect
Tesamorelin GHRH Receptor (Pituitary) Stimulates GH release, specifically reduces visceral fat.
CJC-1295 GHRH Receptor (Pituitary) Long-acting GH release (elevates IGF-1 for days).
Ipamorelin Ghrelin Receptor Selective GH boost (no cortisol/prolactin spikes).
Synergy:
Tesamorelin targets fat stores, while CJC-1295 + Ipamorelin prolong GH benefits for muscle and recovery.
3. Dosage & Administration
Standard Protocol
Blend Ratio: 6mg Tesamorelin + 3mg CJC-1295 + 3mg Ipamorelin per vial.
Daily Dose:
Tesamorelin: 1–2mg/day (e.g., 1mg AM, 1mg PM).
CJC-1295 + Ipamorelin: 100–300mcg each, 1–2x/day (post-workout or bedtime).
Cycle Length: 8–12 weeks (followed by 4-week break).
Reconstitution
Mix with 2–3mL bacteriostatic water (for precise dosing).
Storage: Refrigerate after reconstitution (stable for 4–6 weeks).
4. Expected Results & Timeline
📌 Weeks 1–4:
Reduced bloating, improved sleep, increased energy.
📌 Weeks 4–8:
Visible fat loss (especially abdomen), faster workout recovery.
📌 Weeks 8–12:
Lean muscle definition, tighter skin, enhanced endurance.
(Optimal with strength training + low-sugar diet.)
Final Verdict
✅ Best for:
Men/women targeting stubborn belly fat.
Athletes wanting muscle preservation + recovery.
Anti-aging (skin, cognition, longevity).
Description
Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection.
This medicine is available only with your doctor's prescription.
This product is available in the following dosage forms:
Description
Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection.
This medicine is available only with your doctor's prescription.
This product is available in the following dosage forms:
Tesamorelin may sometimes be given at home to patients who do not need to be in a hospital or clinic. If you are using this medicine at home, your doctor or nurse will teach you how to prepare and inject the medicine. Be sure that you understand how to use the medicine.
Tesamorelin injection comes with a patient information leaflet and patient instructions. Read the instructions and make sure you understand:
How to prepare the injection.
Proper use of disposable syringes.
How to give the injection.
How long the injection is stable.
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Testosterone acetate is a short-acting testosterone ester. It releases testosterone more quickly than longer esters like enanthate or cypionate.
Although testosterone acetate is not as commonly prescribed today compared to other esters, it can be used for:
• Testosterone Replacement Therapy (TRT)
For men with hypogonadism, to restore normal physiological testosterone levels.
Benefits of medically supervised TRT may include:
Improved libido
Better energy and mood
Increased muscle mass
Improved bone density
Better erectile function
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Testosterone decanoate is a long-acting ester of testosterone. It’s most commonly found as part of Sustanon 250 (a blend of multiple testosterone esters), though it can also be produced as a standalone compound.
1. Testosterone Replacement Therapy (TRT)
Used to treat male hypogonadism, a condition where the body does not produce enough testosterone. TRT may help improve:
Low libido
Fatigue
Mood disturbances
Loss of muscle mass
Erectile dysfunction
Low bone density
Because the decanoate ester has a long half-life, it provides slow, steady release of testosterone.
2. Delayed Puberty in Males
Occasionally used under medical supervision to initiate and support puberty in adolescent males with delayed development.
Testosterone Decanoate Raw powder we export in USA Testosterone Decanoate Raw powder we export to Alabama, Alaska, Arizona, Arkansas, California, ColoradO, Connecticut, Delaware, Florida, Georgia, Hawaii, Idaho, Illinois, Indiana, Iowa, Kansas, Kentuck, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin, Wyoming. Testosterone Propionate Raw powder we export in UK Testosterone Propionate Raw powder we export to London, Birmingham, Manchester, Liverpool, Leeds, Sheffield, Bradford, Bristol, Coventry, Nottingham, Newcastle upon Tyne, Oxford, Cambridge, York, Wakefield, Sunderland, Stoke-on-Trent, Southampton, Sheffield, Salford, Salisbury, Ripon, Truro, Wells, Westminster, Winchester, Wolverhampton, Worcester, Edinburgh, Glasgow, Aberdeen, Dundee, Inverness, Perth, Stirling, Dunfermline, Cardiff, Swansea, Newport, Bangor, St Asaph, St Davids, Wrexham, Belfast, Armagh, Londonderry, Lisburn, Newry, Bangor, Douglas, Hamilton, City of Gibraltar, Stanley, Jamestown. Testosterone Propionate Raw powder we export in UAE Testosterone Propionate Raw powder we export to Abu Dhabi, Al Ain, Al Dhannah, Madinat Zayed, Liwa Oasis, Ghayathi, Ar Ruways, Dubai, Jebel Ali, Hatta, Al Aweer, Al Marmoom, Sharjah, Khor Fakkan, Dibba Al-Hisn, Kalba, Al Dhaid, Mleiha, Al Saja'a, Ajman, Masfout, Umm Al Quwain, Al Sufouh, Ras Al Khaimah, Al Jazirah Al Hamra, Ar-Rams , Fujairah, Dibba Al-Fujairah, Masafi. Testosterone Propionate Raw powder we export in SINGAPORE Testosterone Propionate Raw powder we export to Bishan, Bukit Merah, Bukit Panjang, Bukit Timah, Central Water Catchment, Chinatown, Downtown Core, Geylang, Kallang, Marina East, Marina South, Newton, Orchard, Outram, Queenstown, River Valley, Rochor, Singapore River, Southern Islands, Straits View, Tanglin, Toa Payoh, Bedok, Changi, Changi Bay, Changi Village, East Coast, Pasir Ris, Tampines, Simei, Upper East Coast, Admiralty, Kranji, Lim Chu Kang, Mandai, Sungei Kadut,. Woodlands, Yishun, Ang Mo Kio, Hougang, Kovan, Punggol, Sengkang, Serangoon, Boon Lay, Bukit Batok, Bukit Panjang, Choa Chu Kang, Clementi, Jurong East, Jurong West, Tengah, Tuas, Western Islands, Western Water Catchment. USAGE:- Testosterone decanoate is used primarily in androgen replacement therapy. It is specifically approved for the treatment of hypogonadism in men, breast cancer, low sexual desire, delayed puberty in boys, and menopausal symptoms
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Cenforce Professional 100 mg is a fast-acting and effective sildenafil formulation designed for treating erectile dysfunction, with faster onset due to its chewable/sublingual delivery.
It’s sometimes used off-label for pulmonary hypertension or blood pressure regulation, only on medical advice. It should be used once daily.
USAGE :-
Erectile Dysfunction (ED) in adult men
Inhibits PDE‑5 → increases cGMP → relaxes smooth muscle → boosts blood flow to the penis during sexual arousal.
Takes effect in about 30–60 minutes, lasting 4–6 hours, offering a reliable window for sexual activity.
Sublingual/chewable tablet designed for faster absorption—dissolves under the tongue or is chewed and swallowed.
Dosage :-
Dose: One 100 mg tablet, no more than once every 24 hours
Administration:
Place under tongue or chew thoroughly, then swallow with water
Can be taken with or without food, but avoid high-fat meals—they may delay onset
Form Chewable/sublingual sildenafil 100 mg
Onset 30–60 minutes
Duration 4–6 hours
Dose 1 tablet per 24 hours
Use ED (primary), PAH or BP support (off‑label)
Avoid with Nitrates, heavy meals, alcohol, grapefruit
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