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Spegra 50 200 25 Mg
₹ 4800 / Bottle Get Latest Price
Product Brochure
Dose Strength 50 mg
Manufacture By Emcure Pharmaceuticals Ltd
Packaging Type Bottle
Brand Spegra 50 200 25 Mg
COMPOSITION Dolutegravir (50mg) + Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)
Spegra Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).
Spegra Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine can be taken with or without food. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it. Sudden discontinuation of the treatment may affect the potency of the medicine.
The most common side effects of this medicine are insomnia, fatigue, headache, nausea, adn diarrhea. These side effects are generally temporary, but if they persist or become serious inform your doctor. This medicine can also make you feel lazy or weak, so it is advised to avoid driving. Drinking plenty of fluid can help you to cope up with the side effects, so stay hydrated.
Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any health condition. Your doctor may suggest regular blood tests to check your blood counts, kidney and liver functions, and other health conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse.
Brand name: RIBUTIN
Generic name: Rifabutin
Strength: 150 mg
Dosage form: Capsule
Drug class: Antibiotic (Rifamycin group)
Route of administration: Oral
Composition
Active ingredient: Rifabutin 150 mg
Inactive ingredients: Excipients
Indications
Tuberculosis (TB) – combination therapy
Mycobacterium avium complex (MAC) infection
HIV-associated mycobacterial infections
Uses
Tuberculosis (TB)
Used as part of combination therapy, especially in patients who cannot tolerate rifampicin or have drug-resistant TB
Mycobacterium avium complex (MAC) infection
Prevention and treatment of MAC infection, especially in immunocompromised patients
HIV-related mycobacterial infections
Preferred when there are drug-interaction concerns with antiretroviral medicines
Tamoxifen API (Active Pharmaceutical Ingredient) is the pure, bulk powder form of the drug Tamoxifen Citrate, a key selective estrogen receptor modulator (SERM) used mainly to treat and prevent hormone-receptor-positive breast cancers, working as an anti-estrogen by blocking estrogen's effects on cancer cells.
INN / Common name: Tamoxifen citrate
CAS No.: 54965-24-1
Molecular formula: C₂₈H₃₂N₂O·C₆H₈O₇ (citrate salt)
Molecular weight: ~563.64 g/mol
Breast cancer treatment
For estrogen receptor–positive (ER+) breast cancer in pre- and postmenopausal women.
Used in adjuvant therapy (after surgery) or treatment of metastatic disease.
Breast cancer prevention
In high-risk women, tamoxifen reduces the risk of developing breast cancer.
Other estrogen-related conditions (off-label, limited)
Certain gynecomastia cases in men
Fertility treatments (rare off-label use in women to induce ovulation)
Mechanism of action (brief)
Tamoxifen blocks estrogen receptors in breast tissue, preventing estrogen from promoting tumor growth.
In other tissues (bone, uterus), it may act as a partial agonist, producing estrogen-like effects.
Identification
IR spectroscopy: Conforms to reference spectrum
UV / HPLC: Retention time matches certified reference standard
Melting point: Within reference range (~140–144 °C for citrate salt)
Assay (Potency)
Typically 98.0–102.0% (on anhydrous basis)
The Exemestane Raw Active Pharmaceutical Ingredient (API) is primarily used for manufacturing medications to treat hormone-receptor-positive breast cancer in postmenopausal women.
INN: Exemestane
CAS No.: 107868-30-4
Molecular formula: C₂₀H₂₄O₂
Molecular weight: ~296.41 g/mol
White to off-white crystalline powder
Practically insoluble in water; soluble in organic solvents
Assay (Potency)
Typically 98.0–102.0% (on anhydrous basis)
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✅ NAD⁺ (750 mg) – Uses and Benefits
A 750 mg dose of NAD⁺ is considered a high oral dose for supplementation. At this level, it is often used for more targeted therapeutic effects or in anti-aging protocols, and may be part of high-dose oral or IV regimens.
NAD⁺ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every cell that plays a crucial role in:
Energy production (mitochondrial ATP synthesis)
DNA repair
Cell survival and aging
Activation of sirtuins (longevity-related enzymes)
🧠 Emerging Research Areas
NAD⁺ at this dose is being studied for:
Parkinson’s, Alzheimer’s, and cognitive decline
Chronic fatigue syndrome (ME/CFS)
Immune function in aging (immunosenescence)
NAD+ (750mg) improves mitochondrial health and slows the aging process. Neuroprotection (Brain Health):
NAD+ (750mg) helps protect the health of your neurons and brain health for better mental clarity now and in the future. Mood Regulation: NAD+ is known to have positive effects on mood and mental well-being.
Semorelin (15mg) UK FAST DELIVERY
Sermorelin is used to diagnose and treat poor growth in children. It's also sometimes used off-label to treat hGH deficiency in adults. Some research has suggested that it can be beneficial in people with certain recurrent brain tumors. Children usually benefit the most from sermorelin.
Sermorelin is a peptide hormone that is structurally similar to growth hormone-releasing hormone (GHRH).
positive effects of sermorelin : Antidepressants like sertraline help to improve your mood so you feel better
Popular among aging men and women to mimic youthful GH secretion.
Administration: Nighttime injection to mimic natural GH pulses.
Does Tesamorelin burn fat?
Tesamorelin injection is not used to help with weight loss.
Who can't take sermorelin?
if you are pregnant, planning to become pregnant, or are breast-feeding.
Drug Name Sermorelin Acetate
Form Lyophilized powder (freeze-dried) for reconstitution
Reconstitution Solvent Bacteriostatic Water for Injection (BWFI) or Sterile Water for Injection
Dosing and Administration (Typical)
Dose: Varies by provider and goal, but commonly 0.2–0.5 mg/day, subcutaneously at bedtime.
15 mg vial: Typically used over a 30-day period after being reconstituted with bacteriostatic water.
Administration: Nighttime injection to mimic natural GH pulses.
Improved body composition (more lean mass, less fat)
Better sleep
Enhanced recovery and energy
Possible cognitive and mood improvements
Tesamorelin (5mg) :- USA FAST DELIVERY
Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection.
Tesamorelin injection is used to decrease the amount of extra fat in the stomach area in adults with human immunodeficiency virus (HIV) who have lipodystrophy (increased body fat in certain areas of the body). Tesamorelin injection is not used to help with weight loss.
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Reduced body fat, improved cardiovascular health, and cholesterol management.
Purpose: Tesamorelin is approved for reducing excess abdominal fat in patients with HIV-associated lipodystrophy.
Mechanism: It stimulates the pituitary gland to secrete growth hormone, which reduces visceral (deep abdominal) fat.
General Visceral Fat Reduction
For obese patients or those with metabolic syndrome, though not yet approved for this indication.
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How quickly does tesamorelin work?
Within 1-2 weeks.
Tesamorelin + CJC-1295 + Ipamorelin (6/3/3mg) FAST DELIVERY TO DOORSTEPS
CJC-1295 is an incredibly effective peptide which works by stimulating the release of your own body's growth hormones (which drop quickly after the age of 30). Research has shown that CJC-1295 can increase growth hormone levels by 200-1000% and the elevated growth hormone production continued for up to 6 days.
It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Powder for Solution.
Conclusion: Treatment with tesamorelin was generally well tolerated and resulted in sustained decreases in VAT and triglycerides over 52 weeks without aggravating glucose. Though effects on VAT are sustained during treatment for 52 weeks, these effects do not last beyond the duration of treatment.
Signs of high blood sugar like confusion, feeling sleepy, unusual thirst or hunger, passing urine more often, flushing, fast breathing, or breath that smells like fruit. A fast heartbeat. Dizziness or passing out. Flushing.
1. Primary Medical & Performance Uses
A. Fat Loss (Especially Visceral Fat)
✅ Tesamorelin (6mg):
FDA-approved for HIV lipodystrophy (reduces abdominal fat).
Targets stubborn belly fat even in non-HIV patients.
✅ CJC-1295 (3mg) + Ipamorelin (3mg):
Amplifies growth hormone (GH) pulses for enhanced fat metabolism.
Preserves muscle during calorie deficits.
B. Muscle Growth & Recovery
Boosts IGF-1 levels → Increases protein synthesis.
Accelerates repair of tendons/ligaments (ideal for athletes).
C. Anti-Aging & Longevity
Improves skin elasticity (collagen stimulation).
Enhances sleep quality (GH promotes deep sleep cycles).
May support cognitive function (neuroprotective effects).
D. Metabolic Health
Improves insulin sensitivity (beneficial for prediabetes/metabolic syndrome).
Lowers triglycerides (cardiovascular support).
2. Mechanism of Action
Peptide Target Effect
Tesamorelin GHRH Receptor (Pituitary) Stimulates GH release, specifically reduces visceral fat.
CJC-1295 GHRH Receptor (Pituitary) Long-acting GH release (elevates IGF-1 for days).
Ipamorelin Ghrelin Receptor Selective GH boost (no cortisol/prolactin spikes).
Synergy:
Tesamorelin targets fat stores, while CJC-1295 + Ipamorelin prolong GH benefits for muscle and recovery.
3. Dosage & Administration
Standard Protocol
Blend Ratio: 6mg Tesamorelin + 3mg CJC-1295 + 3mg Ipamorelin per vial.
Daily Dose:
Tesamorelin: 1–2mg/day (e.g., 1mg AM, 1mg PM).
CJC-1295 + Ipamorelin: 100–300mcg each, 1–2x/day (post-workout or bedtime).
Cycle Length: 8–12 weeks (followed by 4-week break).
Reconstitution
Mix with 2–3mL bacteriostatic water (for precise dosing).
Storage: Refrigerate after reconstitution (stable for 4–6 weeks).
4. Expected Results & Timeline
📌 Weeks 1–4:
Reduced bloating, improved sleep, increased energy.
📌 Weeks 4–8:
Visible fat loss (especially abdomen), faster workout recovery.
📌 Weeks 8–12:
Lean muscle definition, tighter skin, enhanced endurance.
(Optimal with strength training + low-sugar diet.)
Final Verdict
✅ Best for:
Men/women targeting stubborn belly fat.
Athletes wanting muscle preservation + recovery.
Anti-aging (skin, cognition, longevity).
Description
Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection.
This medicine is available only with your doctor's prescription.
This product is available in the following dosage forms:
Description
Tesamorelin injection is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection.
This medicine is available only with your doctor's prescription.
This product is available in the following dosage forms:
Tesamorelin may sometimes be given at home to patients who do not need to be in a hospital or clinic. If you are using this medicine at home, your doctor or nurse will teach you how to prepare and inject the medicine. Be sure that you understand how to use the medicine.
Tesamorelin injection comes with a patient information leaflet and patient instructions. Read the instructions and make sure you understand:
How to prepare the injection.
Proper use of disposable syringes.
How to give the injection.
How long the injection is stable.
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Ipamorelin works by binding to IGF-1 receptors in the body and mimicking its effects on those receptors. This causes an increase in muscle mass and strength, as well as fat loss due to increased metabolism and lipolysis (the breakdown of fat).
Semorelin + Ipamorelin (5mg/5mg) – Key Uses, Benefits & Protocol
This growth hormone (GH)-stimulating peptide blend is used for anti-aging, fat loss, muscle growth, and recovery.
1. Primary Uses
A. Anti-Aging & Longevity
Boosts collagen → Improves skin elasticity, reduces wrinkles.
Enhances sleep quality → Deepens REM sleep for cellular repair.
Supports cognitive function → May improve memory/focus.
B. Fat Loss & Metabolism
Reduces stubborn fat (especially visceral/belly fat).
Improves insulin sensitivity → Helps with metabolic disorders.
C. Muscle Growth & Recovery
Increases lean muscle mass (without water retention).
Speeds up injury recovery (tendons, ligaments, joints).
D. Performance Enhancement (Athletes/Bodybuilders)
Enhances workout recovery → Less soreness, faster gains.
Preserves muscle during cutting phases.
2. How It Works
Sermorelin → Stimulates natural GH release from the pituitary.
Ipamorelin → A selective GH secretagogue (avoids cortisol/prolactin spikes).
Synergy: More sustained GH pulses than either peptide alone.
(Unlike synthetic HGH, this combo promotes natural, balanced GH secretion.)
3. Dosage & Administration
Standard Dose: 5mg Sermorelin + 5mg Ipamorelin per vial (mixed with bacteriostatic water).
Daily Injection:
100-300mcg each (e.g., 100mcg Sermorelin + 100mcg Ipamorelin).
Typically 1-2 injections/day (morning and/or before bed).
Cycle Length: 8-12 weeks (then take a 4-week break).
4. Expected Results & Timeline
📌 4-6 Weeks: Better sleep, increased energy, reduced body fat.
📌 8-12 Weeks: Visible muscle tone, tighter skin, faster recovery.
📌 3+ Months: Long-term anti-aging benefits (if cycled properly).
(Best paired with strength training + high-protein diet.)
7. Alternatives to Consider
Peptide Best For Pros Cons
Tesamorelin + Ipamorelin Fat loss (visceral) FDA-approved (for HIV lipodystrophy) Expensive
Final Verdict
✅ Best for:
Anti-aging (skin, cognition, longevity).
Athletes seeking muscle growth + recovery.
Men/women targeting stubborn fat.
. Detailed Benefits & Science
How it compares to HGH or other peptides (like CJC-1295).
Anti-aging mechanisms (collagen, cellular repair).
2. Cycle Recommendations
Optimal dosing (e.g., 100mcg vs. 300mcg per day).
How long to run it (8 vs. 12 weeks).
5. Success Stories/User Experiences
Real-world results for fat loss, muscle gain, or skin improvement.
Increased energy levels: sermorelin and ipamorelin help boost energy and stamina, allowing you to feel more active and engaged throughout the day. Improved sleep quality: By enhancing restorative sleep, sermorelin and ipamorelin can lead to better overall health and well-being.
Sermorelin is a peptide hormone that is structurally similar to growth hormone-releasing hormone (GHRH). It is typically used to treat growth hormone deficiency in children and adults. It can also be used for other conditions, such as improving wound healing, reducing fat mass, and increasing muscle mass.
Sermorelin and Ipamorelin peptides are often combined because they have synergistic properties. Research has proven them to help slow down the aging process, increase muscle mass, decrease fat mass, reduce inflammation, heal the gut and more.
How often should I take Sermorelin? A dosage of 0.2-0.3 mcg once daily at bedtime by subcutaneous injection is recommended.
Ipamorelin is a peptide that has been shown to increase growth hormone levels in humans by stimulating the hypothalamus, which is responsible for regulating the secretion of growth hormone. Ipamorelin works by binding to IGF-1 receptors in the body and mimicking its effects on those receptors. This causes an increase in muscle mass and strength, as well as fat loss due to increased metabolism and lipolysis (the breakdown of fat).
When Can I Expect To See Results?
While patients will notice some significant increases changes in the body after the first month, the full-benefits are usually fully noticed after three to six months of therapy.
Month 1
* Increased energy
* Improved stamina
* Deeper, more restful sleep
Month 2
* Improved skin, reduced wrinkles
* Stronger nails and hair
* Increased metabolism
Month 3
* Enhanced sex drive and performance
* Improved mental focus
* Improved joint health
Month 4
* Continued weight reduction
* Improved skin elasticity
* Increased lean muscle mass
Month 5
* Noticeably fuller and healthier hair
* Reduced appearance of wrinkles, better skin tone
* Continued reduction in belly fat
Month 6
* 5-10% reduction in body fat (without exercise/diet)
* 10% increase in lean muscle mass
* Improved vitality due to organ regrowth
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Growth Hormone Secretagogues
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