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Sexual & Reproductive Health Peptides

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Generic Name :- Kisspeptin-10 Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins 1. Stimulation of Gonadotropin-Releasing Hormone (GnRH) Kisspeptin-10 stimulates the hypothalamus to release GnRH, which then promotes the secretion of: Luteinizing hormone (LH) Follicle-stimulating hormone (FSH) This cascade is crucial for puberty onset, ovulation, and fertility regulation. 2. Fertility Research Used in assisted reproductive technologies (ART) and IVF studies to promote natural hormonal responses. Can potentially reduce the need for synthetic hormones like hCG. 3. Hypogonadism and Delayed Puberty Investigated as a treatment for hypogonadotropic hypogonadism (low LH/FSH due to low GnRH). May help restore reproductive function in affected individuals. 4. Polycystic Ovary Syndrome (PCOS) Studied for its role in correcting LH/FSH imbalances in PCOS patients. 5. Diagnostic Use Used to test pituitary function or the integrity of the hypothalamic-pituitary-gonadal (HPG) axis. BUY Kisspeptin-10 5mg IN CHEAP PRICE GET BEST OFFERS ON Kisspeptin-10 5mg FROM US SKYBLUE INTERNATIONAL

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NAD+ & Mitochondrial Support Peptides

Contact Us on telegram or WhatsApp +917887449821‬ ‪+919168783773‬ +91 9529672584‬ +91 7499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ ✅ NAD⁺ (750 mg) – Uses and Benefits A 750 mg dose of NAD⁺ is considered a high oral dose for supplementation. At this level, it is often used for more targeted therapeutic effects or in anti-aging protocols, and may be part of high-dose oral or IV regimens. NAD⁺ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every cell that plays a crucial role in: Energy production (mitochondrial ATP synthesis) DNA repair Cell survival and aging Activation of sirtuins (longevity-related enzymes) 🧠 Emerging Research Areas NAD⁺ at this dose is being studied for: Parkinson’s, Alzheimer’s, and cognitive decline Chronic fatigue syndrome (ME/CFS) Immune function in aging (immunosenescence) NAD+ (750mg) improves mitochondrial health and slows the aging process. Neuroprotection (Brain Health): NAD+ (750mg) helps protect the health of your neurons and brain health for better mental clarity now and in the future. Mood Regulation: NAD+ is known to have positive effects on mood and mental well-being.

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NAD+ & Mitochondrial Support Peptides

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ NAD+ (Nicotinamide adenine dinucleotide), in a 100mg dose from Peptide Science, is used for a variety of potential benefits related to cellular health and function. These include supporting energy production, DNA repair, and combating the effects of aging. NAD+ plays a crucial role in numerous cellular processes, making it a subject of interest for both its potential therapeutic applications and its role in healthy aging. Energy Production: NAD+ is essential for the cellular energy production process, particularly in the mitochondria. It acts as a coenzyme, facilitating the transfer of electrons in redox reactions, which are crucial for ATP (energy) production. DNA Repair: NAD+ is a substrate for enzymes called PARPs, which play a vital role in repairing DNA damage. Maintaining sufficient NAD+ levels can help ensure proper DNA repair and genomic stability. ✅ Primary Uses of NAD⁺ (100mg) Cellular Energy Production NAD⁺ is essential for mitochondrial function, helping convert nutrients into ATP (energy). Often used to combat fatigue or low energy levels. Healthy Aging & Longevity NAD⁺ levels decline with age. Supplementation may support DNA repair, cellular health, and overall longevity via sirtuin activation (especially SIRT1). Cognitive Function May enhance brain health, memory, and focus by supporting neuronal function and reducing oxidative stress. Metabolic Support Helps regulate metabolism, insulin sensitivity, and weight management. May support healthy blood sugar levels. Addiction & Withdrawal Support (High-dose clinical setting) NAD⁺ IV therapy is sometimes used in detox programs to ease withdrawal symptoms and improve mental clarity. 100 mg is a low dose; IV protocols often use much higher amounts. Skin and Anti-Aging Products Included in some topical formulations to promote skin cell repair and reduce signs of aging. Sirtuin Activation: NAD+ is also required by sirtuins, a class of proteins involved in gene regulation, cellular stress responses, and potentially, longevity. Anti-Aging: Because NAD+ is involved in so many fundamental cellular processes, its decline with age is linked to various age-related changes. Maintaining NAD+ levels through supplementation is being explored as a way to potentially mitigate some of these changes and promote healthy aging.

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Metabolic & Weight Management Peptides

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+91 9529672584‬ ‪+91 7499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ AOD9604 5mg retains the bone stimulating properties of human Growth Hormone. AOD9604 indicates that this drug may have a role in the prevention and possible treatment of osteoporosis, through direct action on osteoblasts, the cells which build new bone. AOD 9604 (5mg) is a synthetic peptide derived from the C-terminal fragment of human growth hormone (hGH). It has been studied for its potential benefits in fat metabolism and weight management. ✅ Uses of AOD 9604 Fat Loss and Weight Management AOD 9604 has been shown to stimulate lipolysis (the breakdown of fat) and inhibit lipogenesis (the formation of new fat), potentially aiding in fat loss and weight management. Targeted Fat Reduction The peptide may help reduce fat in specific areas, such as the abdominal region, by promoting the breakdown of stored fat. Improved Metabolism AOD 9604 may enhance metabolic rate, leading to increased calorie burning and potentially supporting weight loss efforts. Muscle Preservation Unlike some weight loss methods, AOD 9604 may help preserve lean muscle mass during fat loss, contributing to improved body composition. Bone and Cartilage Repair Some studies suggest that AOD 9604 may have regenerative properties, potentially aiding in the repair of bone and cartilage tissue. Enhanced Exercise Recovery The peptide may support faster recovery from exercise-induced muscle damage, reducing soreness and improving performance. ⚠️ Important Considerations Administration: AOD 9604 is typically administered via subcutaneous injection Dosage: Common dosing ranges from 300–500 mcg per day, depending on individual goals and protocols. Duration: Treatment cycles often last between 4 to 12 weeks, followed by breaks to assess effectiveness and reduce potential side effects. Consultation: It's crucial to consult with a healthcare professional before starting AOD 9604 therapy to ensure it's appropriate for your individual health needs and goals. AOD 9604 peptide therapy is considered a safe and effective solution for weight loss.

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Growth Hormone Secretagogues

The first 29 amino acids of GHRH were discovered to be as equally potent as its full 44 amino acid structure[1][2] This fragment became known as GRF (1-29). However, due to a rapid metabolic clearance analogues of GRF (1-29) were synthesized to enhance the biological activity and reduce the rapidity of metabolic clearance. These analogues were primarily created by substituting amino acids within the peptide structure for amino acids more resistant to enzymatic cleavage. One early analogue substituted the amino acid L-alanine (abbreviated as Ala or A) at the 2nd position of the peptide structure for its optical isomer (mirror image), D-alanine (abbreviated as D-Ala). This substitution resulted in a peptide bond between D-Ala and the 3rd amino acid in the structure aspartic acid (Asp) more able to resist rapid cleavage by the enzyme dipeptidyl peptidase-4, a cleavage which had previously led to an inactive peptide fragment.[3][4] This successful modification prompted the further creation of analogues with additional amino acid substitutions. Ipamorelin: A selective growth hormone secretagogue, Ipamorelin stimulates the release of GH by mimicking ghrelin's action on the ghrelin receptor. It is known for its specificity and minimal side effects compared to other GH-releasing peptides. Mod GRF 1-29 (CJC-1295 without DAC): This is a modified version of the first 29 amino acids of growth hormone-releasing hormone (GHRH). The modifications extend its half-life and enhance its ability to stimulate the pituitary gland to release GH. It is often used in research to study GH secretion patterns and related metabolic effects. ⚖️ Dosage and Composition The 5/5 mg blend indicates that each vial contains 5 mg of Mod GRF 1-29 and 5 mg of Ipamorelin, totaling 10 mg per vial. This combination is designed to provide a balanced stimulation of GH release, potentially offering synergistic effects when used in research protocols. 🔬 Research Applications In scientific studies, this peptide blend is utilized to: Study Growth Hormone Dynamics: Investigating the patterns and regulation of GH secretion. Metabolic Research: Understanding the role of GH in metabolism, including fat metabolism and muscle growth. Aging and Longevity Studies: Exploring the effects of GH on aging processes and potential therapeutic applications. Sleep and Recovery Research: Examining how GH influences sleep patterns and recovery processes. ⚠️ Important Considerations Research Use Only: These peptides are intended strictly for laboratory research and are not approved for human or veterinary use. Legal Status: The legality of purchasing and possessing these peptides varies by country and jurisdiction. It's essential to consult local regulations before acquiring them. Storage and Handling: Proper storage conditions are crucial to maintain peptide stability. Typically, lyophilized peptides should be stored at -20°C or colder and protected from light. Reconstitution should be done with appropriate solvents, and solutions should be stored at 4°C and used within a specified timeframe. Mod GRF 1-29 + Ipamorelin (5/5 mg) is primarily used in scientific research and clinical studies to investigate its effects on human growth hormone (GH) release and related metabolic functions. It is not FDA-approved for general medical use, but here are the commonly researched uses and potential applications: Stimulation of Growth Hormone (GH) Release Both peptides work synergistically to enhance the natural pulsatile release of GH from the pituitary gland. Mod GRF 1-29 initiates GH release, while Ipamorelin amplifies it by mimicking ghrelin. Anti-Aging Studies GH has regenerative effects on tissues, so researchers study this combo to explore its potential for: Improving skin elasticity Increasing energy levels Enhancing sleep quality Muscle Growth and Recovery (in studies) GH can help stimulate muscle protein synthesis and recovery. This combo is sometimes researched for its effects on lean muscle mass and exercise recovery. Fat Loss & Metabolic Support GH mobilizes stored fat, making this blend of interest in obesity and metabolic syndrome research. May support lipolysis (fat breakdown) in clinical models. Bone Density Studies GH supports bone mineralization. This combo is explored for potential applications in osteopenia/osteoporosis research. Sleep Improvement GH release is tied to deep sleep stages; researchers observe whether this combo improves sleep architecture and REM sleep. Modified GRF (1-29) acts to increase growth hormone production and release by binding to the growth-hormone-releasing hormone receptor (GHRHR) on cells in the anterior pituitary.

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Erectile Dysfunction Medicines

TADALAFIL, VIDALISTA 40mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, UK, EUROPE, UAE & GET 20% OFF ON BULK ORDER Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ Mechanism of Action: Tadalafil, the active ingredient in Vidalista 40mg, belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. These medications work by relaxing the muscles in the penis and increasing blood flow, which facilitates an erection when a man is sexually aroused. Vidalista 40mg, containing the active ingredient Tadalafil, is primarily used to treat erectile dysfunction (ED) in men. It helps men achieve and maintain an erection by increasing blood flow to the penis. Tadalafil is a PDE5 inhibitor and is also sometimes prescribed for symptoms of benign prostatic hypertrophy. Erectile Dysfunction (ED): Vidalista 40mg is commonly prescribed to help men with ED achieve and sustain an erection sufficient for sexual intercourse. Mechanism of Action: Tadalafil works by inhibiting the PDE5 enzyme, which helps relax the muscles in the penis and allows for increased blood flow. Dosage and Administration: Typically, Vidalista 40mg is taken orally at least 30 minutes before sexual activity. The typical maximum dose for ED is 20mg, and taking 40mg could potentially increase the risk of side effects. It's crucial to follow the dosage instructions provided by a healthcare professional. Erectile Dysfunction (ED) Aids in achieving and sustaining an erection when there’s sexual stimulation, thanks to increased blood flow to the penis. Typically taken 30–60 minutes before intercourse, with effects lasting up to 36 hours—often dubbed the “weekend pill” Benign Prostatic Hyperplasia (BPH) Relaxes bladder and prostate muscles, alleviating urinary issues like weak stream, frequent urges, and hesitancy Pulmonary Arterial Hypertension (PAH) (dosages around 40 mg daily) Helps relax pulmonary blood vessels, lowering lung artery pressure and improving exercise capability

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Erectile Dysfunction Medicines

TADALAFIL, VIDALISTA 10mg BUY IN CANADA, SINGAPORE, AUSTRALIA, USA, UK, EUROPE, UAE & GET 20% OFF ON BULK ORDER Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪ +919529672584‬ ‪ +917499402610 Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.medicinesfromindia.com/ Vidalista 10mg, which contains the active ingredient tadalafil, is primarily used to treat erectile dysfunction (ED) in men. It works by increasing blood flow to the penis, which can help a man achieve and maintain an erection when sexually stimulated. However, it's important to note that Vidalista 10mg does not cause an erection without sexual stimulation. Erectile Dysfunction Treatment: Vidalista 10mg is prescribed to help men with ED achieve and sustain an erection during sexual activity. Mechanism of Action: Tadalafil, the active ingredient in Vidalista 10mg, belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. These medications work by relaxing the muscles in the penis and increasing blood flow, which facilitates an erection when a man is sexually aroused. Sexual Stimulation Required: It's crucial to understand that Vidalista 10mg does not cause an erection on its own. Sexual stimulation is necessary for the medication to be effective. How & When to Take It : Standard ED dosage: 10 mg, taken 30–60 minutes before sexual activity; can be increased to 20 mg or decreased to 5 mg based on effectiveness and tolerance Take with water, with or without food (heavy meals might slow absorption) Maximum: One dose per 24 hours, though daily low-dosing is permitted under a doctor’s direction. BUY IT NOW

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Miscellaneous Peptides

Follistatin 315 (1mg), Peptide BUY IN USA, CANADA, SINGAPORE, AUSTRALIA Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪+919529672584‬ ‪ +917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Muscle Growth & Regeneration Binds and neutralizes myostatin, a regulator that limits muscle size, promoting both hypertrophy (growth of existing muscle fibers) and hyperplasia (production of new fibers). Anti‑Inflammatory Effects Blocks activin (part of the TGF-β family) that drives inflammation. Shows benefit in lab models of rheumatoid arthritis, asthma, and fibrosis, reducing tissue damage Tissue Repair & Angiogenesis Supports endothelial cell function, enhancing blood vessel growth and repair — promising in ischemia, wound healing, and post-injury recovery Kidney & Cardiovascular Research In animal models of chronic kidney disease, FST‑315 reduced oxidative stress, inflammation, and fibrosis. Elevated follistatin levels also track with onset of cardiovascular changes, suggesting potential as a diagnostic biomarker Fertility & Development Originally discovered in ovarian fluid; plays roles in regulating fertility, embryo development, and FSH (follicle-stimulating hormone) suppression FAST DELIVERY IN TEXAS FOR Follistatin 315 1mg peptide FAST DELIVERY IN FLORIDA FOR Follistatin 315 1mg peptide FAST DELIVERY IN NEW YORK FOR Follistatin 315 1mg peptide

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Sexual & Reproductive Health Peptides

Gonadorelin 10mg , Peptide USA FAST DELIVERY Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+919529672584‬ ‪+917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ 1. 🎯 Diagnostic Testing of the HPG Axis Used to assess pituitary function by measuring LH/FSH response—helpful in diagnosing hypogonadism or pituitary disorders . 2. 👩‍🔬 Female Infertility & Ovulation Induction Triggers ovulation in women with irregular periods Widely used in IVF and ART, often combined with hCG, to improve ovarian response and implantation rates 3. 👨 Male Hypogonadism & Delayed Puberty Stimulates testosterone and spermatogenesis in male hypogonadotropic hypogonadism and delayed puberty Helps prevent testicular atrophy during TRT and promotes natural LH/FSH production 4. 🧬 Hormone-Sensitive Cancers (Experimental) Explored in breast and prostate cancer to suppress estrogen/testosterone over long-term use . 5. 🦴 Bone, Muscle & Metabolic Health (Research) Preliminary studies show benefits for bone density, muscle strength, mood, and metabolic function via hormone regulation . 6. 🧠 Neurological & Cognitive Research Emerging research on GnRH analogues for potential applications in Alzheimer's disease and cognitive health Diagnosing HPG axis function Boosting fertility and managing reproductive disorders Treating male hormonal deficiencies and puberty delay Evaluating emerging roles in cancer, veterinary fertility, bone/muscle health, and neurology FAST DELIVERY FOR USA FAST DELIVERY FOR UK FAST DELIVERY FOR CANADA FAST DELIVERY FOR AUSTRALIA FAST DELIVERY FOR ABU DHABI FAST DELIVERY FOR SINGAPORE

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