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Growth Hormone Secretagogues

The first 29 amino acids of GHRH were discovered to be as equally potent as its full 44 amino acid structure[1][2] This fragment became known as GRF (1-29). However, due to a rapid metabolic clearance analogues of GRF (1-29) were synthesized to enhance the biological activity and reduce the rapidity of metabolic clearance. These analogues were primarily created by substituting amino acids within the peptide structure for amino acids more resistant to enzymatic cleavage. One early analogue substituted the amino acid L-alanine (abbreviated as Ala or A) at the 2nd position of the peptide structure for its optical isomer (mirror image), D-alanine (abbreviated as D-Ala). This substitution resulted in a peptide bond between D-Ala and the 3rd amino acid in the structure aspartic acid (Asp) more able to resist rapid cleavage by the enzyme dipeptidyl peptidase-4, a cleavage which had previously led to an inactive peptide fragment.[3][4] This successful modification prompted the further creation of analogues with additional amino acid substitutions. Ipamorelin: A selective growth hormone secretagogue, Ipamorelin stimulates the release of GH by mimicking ghrelin's action on the ghrelin receptor. It is known for its specificity and minimal side effects compared to other GH-releasing peptides. Mod GRF 1-29 (CJC-1295 without DAC): This is a modified version of the first 29 amino acids of growth hormone-releasing hormone (GHRH). The modifications extend its half-life and enhance its ability to stimulate the pituitary gland to release GH. It is often used in research to study GH secretion patterns and related metabolic effects. ⚖️ Dosage and Composition The 5/5 mg blend indicates that each vial contains 5 mg of Mod GRF 1-29 and 5 mg of Ipamorelin, totaling 10 mg per vial. This combination is designed to provide a balanced stimulation of GH release, potentially offering synergistic effects when used in research protocols. 🔬 Research Applications In scientific studies, this peptide blend is utilized to: Study Growth Hormone Dynamics: Investigating the patterns and regulation of GH secretion. Metabolic Research: Understanding the role of GH in metabolism, including fat metabolism and muscle growth. Aging and Longevity Studies: Exploring the effects of GH on aging processes and potential therapeutic applications. Sleep and Recovery Research: Examining how GH influences sleep patterns and recovery processes. ⚠️ Important Considerations Research Use Only: These peptides are intended strictly for laboratory research and are not approved for human or veterinary use. Legal Status: The legality of purchasing and possessing these peptides varies by country and jurisdiction. It's essential to consult local regulations before acquiring them. Storage and Handling: Proper storage conditions are crucial to maintain peptide stability. Typically, lyophilized peptides should be stored at -20°C or colder and protected from light. Reconstitution should be done with appropriate solvents, and solutions should be stored at 4°C and used within a specified timeframe. Mod GRF 1-29 + Ipamorelin (5/5 mg) is primarily used in scientific research and clinical studies to investigate its effects on human growth hormone (GH) release and related metabolic functions. It is not FDA-approved for general medical use, but here are the commonly researched uses and potential applications: Stimulation of Growth Hormone (GH) Release Both peptides work synergistically to enhance the natural pulsatile release of GH from the pituitary gland. Mod GRF 1-29 initiates GH release, while Ipamorelin amplifies it by mimicking ghrelin. Anti-Aging Studies GH has regenerative effects on tissues, so researchers study this combo to explore its potential for: Improving skin elasticity Increasing energy levels Enhancing sleep quality Muscle Growth and Recovery (in studies) GH can help stimulate muscle protein synthesis and recovery. This combo is sometimes researched for its effects on lean muscle mass and exercise recovery. Fat Loss & Metabolic Support GH mobilizes stored fat, making this blend of interest in obesity and metabolic syndrome research. May support lipolysis (fat breakdown) in clinical models. Bone Density Studies GH supports bone mineralization. This combo is explored for potential applications in osteopenia/osteoporosis research. Sleep Improvement GH release is tied to deep sleep stages; researchers observe whether this combo improves sleep architecture and REM sleep. Modified GRF (1-29) acts to increase growth hormone production and release by binding to the growth-hormone-releasing hormone receptor (GHRHR) on cells in the anterior pituitary.

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Miscellaneous Peptides

Prostamax 20mg, Peptide BUY IN USA, CANADA, SINGAPORE, AUSTRALIA Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪+919529672584‬ ‪ +917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Prostate Health & BPH support Designed to improve prostate function, reduce enlargement (BPH), and ease urinary symptoms (frequent urination, weak stream) It supports prostate cell regeneration, improves urine flow, and helps alleviate conditions like prostatitis Anti-inflammatory action in prostate tissue Exhibits localized anti-inflammatory effects in models of prostatitis and BPH Chromatin modulation & cellular reparative effects Alters DNA/chromatin structure — increasing chromatin accessibility, gene expression, and markers of DNA activity in prostate and lymphocyte cultures. Anti-aging / epigenetic influences Acts as an “anti-aging” peptide with epigenetic/regulatory effects, potentially applicable beyond prostate tissue. Mechanism of Action :- Sequence: Lys‑Glu‑Asp‑Pro (KEDP), molecular weight ~487 g/mol Chromatin remodeling: Promotes decondensation of heterochromatin, elevates sister chromatid exchange and rRNA gene activity — enabling DNA repair and expression Tissue regeneration: In vitro and animal models show reduced swelling, immune infiltration, and tissue scarring in prostate Dosage & Administration Common protocols: ~500–750 µg/day for 2–4 weeks via subcutaneous injection . Aspect Details Peptide Sequence Lys‑Glu‑Asp‑Pro (KEDP) Target Areas Prostate tissue, urinary system, lymphocytes Key Actions Anti-inflammatory, tissue repair, chromatin remodeling Dose Range ~500–750 µg/day via sub‑Q injection Typical Course 2–4 weeks, sometimes repeated after break Status Research only — not for clinical use BUY IN CANADA BUY IN SINGAPORE BUY IN AUSTRALIA BUY IN USA BUY IN ABU DHABI

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Miscellaneous Peptides

Bronchogen 20mg, Peptide BUY IN CANADA, SINGAPORE, AUSTRALIA Contact Us on telegram or WhatsApp ‪ +917887449821‬ ‪ +919168783773‬ ‪+919529672584‬ ‪ +917499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ Peptide-Based Lung Support Acts as a bioregulator, targeting lung tissue at the cellular level—enhancing DNA stability, reducing inflammation, and promoting epithelial repair and surfactant production in preclinical studies Investigated for potential in chronic respiratory conditions like COPD, asthma, and bronchitis—reducing mucus, bronchospasm, and coughing Anti-Inflammatory & Anti-Aging May stabilize DNA, reduce inflammatory cytokines, and support healthy lung function—promising for age-related lung decline Immunomodulation Proposed to support immune function in the lungs, reducing exacerbations in smokers and older individuals Bronchogen 20 mg is a promising experimental peptide aimed at improving lung structure and function. While early data—both preclinical and anecdotal—suggest benefits for inflammation and airflow, it remains unapproved and under-researched. If you're exploring respiratory support, consult a medical professional and consider established therapies (e.g., bronchodilators, inhaled steroids). WORLD WIDE SHIPPING SHIPPING TO YOUR DOOR STEPS

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Metabolic & Weight Management Peptides

Contact Us on telegram or WhatsApp ‪+917887449821‬ ‪+919168783773‬ ‪+91 9529672584‬ ‪+91 7499402610‬ Mail :- skyblueinternational033@gmail.com internationalskyblue@gmail.com Viwe our catalog :- https://www.skyblueinternationals.com/ AOD9604 5mg retains the bone stimulating properties of human Growth Hormone. AOD9604 indicates that this drug may have a role in the prevention and possible treatment of osteoporosis, through direct action on osteoblasts, the cells which build new bone. AOD 9604 (5mg) is a synthetic peptide derived from the C-terminal fragment of human growth hormone (hGH). It has been studied for its potential benefits in fat metabolism and weight management. ✅ Uses of AOD 9604 Fat Loss and Weight Management AOD 9604 has been shown to stimulate lipolysis (the breakdown of fat) and inhibit lipogenesis (the formation of new fat), potentially aiding in fat loss and weight management. Targeted Fat Reduction The peptide may help reduce fat in specific areas, such as the abdominal region, by promoting the breakdown of stored fat. Improved Metabolism AOD 9604 may enhance metabolic rate, leading to increased calorie burning and potentially supporting weight loss efforts. Muscle Preservation Unlike some weight loss methods, AOD 9604 may help preserve lean muscle mass during fat loss, contributing to improved body composition. Bone and Cartilage Repair Some studies suggest that AOD 9604 may have regenerative properties, potentially aiding in the repair of bone and cartilage tissue. Enhanced Exercise Recovery The peptide may support faster recovery from exercise-induced muscle damage, reducing soreness and improving performance. ⚠️ Important Considerations Administration: AOD 9604 is typically administered via subcutaneous injection Dosage: Common dosing ranges from 300–500 mcg per day, depending on individual goals and protocols. Duration: Treatment cycles often last between 4 to 12 weeks, followed by breaks to assess effectiveness and reduce potential side effects. Consultation: It's crucial to consult with a healthcare professional before starting AOD 9604 therapy to ensure it's appropriate for your individual health needs and goals. AOD 9604 peptide therapy is considered a safe and effective solution for weight loss.

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Anti Cancer capsules

Product introduction Tasigna 200mg Capsule is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects. Tasigna 200mg Capsule should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Headache, nausea, abdominal pain, and rash are very common side effects of this medicine. If you experience severe diarrhea, consult with your doctor or drink plenty of fluids while on treatment. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and blood uric acid levels and blood sugar or fat level in the body. Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy. How to use Tasigna Capsule Take this medicine in the dose and duration as advised by your doctor. Tasigna 200mg Capsule is to be taken empty stomach. How Tasigna Capsule works Tasigna 200mg Capsule is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells. Safety advice 🔹 Primary Use Tasigna is used to treat: ✅ Chronic Myeloid Leukemia (CML) Specifically, Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia. It is used in patients: Who are newly diagnosed with chronic phase CML, or Whose disease has resisted or not responded to previous treatments like imatinib (Gleevec). 🧬 How It Works: Tasigna is a tyrosine kinase inhibitor. It blocks the activity of the BCR-ABL protein, which is produced by the Philadelphia chromosome and causes cancer cells to grow. By blocking this protein, Tasigna helps stop the growth of cancer cells. 📋 Common Dosage Typically: 200 mg taken twice daily, on an empty stomach. Must be taken at least 2 hours after eating and 1 hour before the next meal. 📄 Tasigna 200 mg Capsule – Specification Sheet 🔹 Brand Name: Tasigna 🔹 Generic Name: Nilotinib hydrochloride monohydrate 🔹 Strength: 200 mg per capsule 🔹 Dosage Form: Hard gelatin capsule 🔹 Route of Administration: Oral (by mouth) 🧪 Pharmacological Class: Tyrosine Kinase Inhibitor (TKI) Targets BCR-ABL protein (abnormal tyrosine kinase from the Philadelphia chromosome) 🧪 Pharmacological Class: Tyrosine Kinase Inhibitor (TKI) Targets BCR-ABL protein (abnormal tyrosine kinase from the Philadelphia chromosome) ✅ Indications (Diseases Treated): Philadelphia chromosome-positive Chronic Myeloid Leukemia (Ph+ CML): Chronic Phase (newly diagnosed) Chronic or Accelerated Phase (resistant or intolerant to prior therapy, including imatinib) Typical adult dose: 200 mg twice daily Must be taken on an empty stomach At least 2 hours after a meal Do not eat for 1 hour after taking it Typical adult dose: 200 mg twice daily Must be taken on an empty stomach At least 2 hours after a meal Do not eat for 1 hour after taking it Typical adult dose: 200 mg twice daily Must be taken on an empty stomach At least 2 hours after a meal Do not eat for 1 hour after taking it Typical adult dose: 200 mg twice daily Must be taken on an empty stomach At least 2 hours after a meal Do not eat for 1 hour after taking it vTypical adult dose: 200 mg twice daily Must be taken on an empty stomach At least 2 hours after a meal Do not eat for 1 hour after taking it Typical adult dose: 200 mg twice daily Must be taken on an empty stomach At least 2 hours after a meal Do not eat for 1 hour after taking it 🎯 Main Disease Treated: ✅ Chronic Myeloid Leukemia (CML) A type of blood cancer that affects the white blood cells and the bone marrow. WE EXPORT TO USA WE EXPORT TO UK WE EXPORT TO AUSTRALIA WE EXPORT TO UAE WE EXPORT TO SINGAPORE WE EXPORT TO ITALY WE EXPORT TO CANADA WE ARE A DROPSHIPPER

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Pharmaceutical Tablets

CRESTOR 40 MG (1X10) Crestor 40mg Tablet belongs to a group of medicines called statins. It is used to lower cholesterol and reduce the risk of heart disease. Cholesterol is a fatty substance that builds up in your blood vessels and causes narrowing, which may lead to a heart attack or stroke. Crestor 40mg Tablet is a widely prescribed medicine and is regarded as safe for long-term use. It can be taken with a meal or on an empty stomach. You can take it at any time of the day but try to take it at the same time each day. Most people with high cholesterol do not feel ill, but stopping your medicine may increase your cholesterol levels, making your condition worse and increasing your risk of heart disease and stroke. It is important to have your cholesterol levels checked regularly. This medicine is only one part of the treatment program which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to avoid foods that are high in fat. Common side effects of this medicine include muscle pain, weakness, nausea, headache, and stomach pain. These are usually mild and disappear after a short time. Consult your doctor if they persist or if you notice any yellowing of your eyes or get repeated or unexplained muscle pains. This medicine should not be used in conditions such as liver disease. Also, pregnant women and breastfeeding mothers should not take this medicine as it may harm the developing baby. Diabetic patients should monitor their blood sugar levels while taking this medicine, as it may lead to an increase in blood sugar levels.

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Pharmaceutical Tablets

PREGALYV 75 MG, PREGABALIN Capsules Pregaliv 75 Tablet SR is a prescription medicine used for the treatment of neuropathic pain. It decreases pain by modulating calcium channel activity of the nerve cells. This medicine also protects nerve fibers and heal damaged nerve cells. Pregaliv 75 Tablet SR is taken by mouth with or without food, preferably at bedtime. It is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as this is a habit-forming medicine. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor. Some common side effects of this medicine include nasopharyngitis, increased appetite, euphoric mood, tremor, blurred vision, dry mouth, dizziness, and sleepiness. Do not drive or do anything that requires mental focus until you know how this medicine affects you. The side effects are mild in nature and get improve with time. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. ⚙️ How It Works Pregabalin, the active ingredient, binds to calcium channels in the central nervous system, inhibiting excitatory neurotransmitter release. This action helps in reducing abnormal electrical activity in the brain and alleviates pain by calming overactive nerves. ⚠️ Side Effects Common Side Effects: Dizziness Drowsiness Dry mouth Weight gain Swelling of hands or feet Blurred vision Difficulty concentratingWellness Forever+1Wellness Forever+1 Serious Side Effects: Severe allergic reactions (e.g., trouble breathing, swelling of the face or throat) Mood or mental changes (e.g., depression, suicidal thoughts) Unusual fatigue or weakness Vision problems If you experience any of these serious side effects, seek medical attention promptly. ⚠️ Warnings & Precautions Allergic Reactions: Do not take Pregalyv 75 mg if you are allergic to pregabalin or any other ingredients. Pregnancy & Breastfeeding: Consult your doctor before use during pregnancy or breastfeeding. Kidney Function: Use with caution in patients with kidney problems; dosage adjustments may be necessary. CNS Effects: May cause dizziness, drowsiness, and blurred vision. Avoid activities requiring full alertness until you know how the medication affects you. Alcohol Interaction: Avoid alcohol as it can increase the risk of side effects like drowsiness and dizziness.

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Anti Cancer Tablets

LENVANAMO CAPSULE 10 MG ₹ 6100 / Box Get Latest Price Product Brochure Strength 10 mg Packaging Size 30 Capsules Packaging Type Bottle Brand LENVANAMO COMPOSITION Lenvatinib (4mg) Marketer Shivnaam Tradelink Llp lenvanamo Capsule is used to treat certain types of thyroid cancer. It works by blocking specific proteins that promote cancer cell growth and spread. This helps slow the progression of the disease and may reduce tumor size in affected individuals. lenvanamo Capsule can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include tiredness, joint pain, muscle pain, nausea, low blood pressure, fatigue, diarrhea, and vomiting. It might also cause severe headache, confusion, problems with your eyesight, and difficult talking. If happens, your doctor may checked you for blood pressure as these might be symptom of high blood pressure. If you experience severe diarrhea, then consult with your doctor or drink plenty of fluids. Let your doctor know about severe abdominal pain or black, tarry, or bloody stools as it might be symptoms of bleeding disorder. You may be asked for some blood tests to check for liver, kidney, and level of thyroid stimulating hormones. Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.

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Anti Cancer Tablets

OKAMET 500 MG Tablet ₹ 113 / Strip Get Latest Price Product Brochure Strength 500 mg Pack Type Strip Brand OKAMET 500 MG Manufacturer Cipla Ltd Shelf Life 24 Months Prescription / Non Prescription Non Prescription composition Metformin (500mg) Country of Origin Made in India Okamet 500 Tablet is a medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels and thus prevent serious complications of diabetes. It is also used to treat a menstruation-related disorder known as Polycystic ovary syndrome (PCOS) in women. Okamet 500 Tablet is best taken with food to avoid nausea and abdominal pain. You should take it regularly, at the same time each day, to get the most benefit. You should not stop taking this medicine unless your doctor recommends it. Your lifestyle plays a big part in controlling diabetes. Therefore, it is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. The most common side effects of this medicine include diarrhea, nausea, vomiting, flatulence, weakness, indigestion, abdominal discomfort, headache, and loss of appetite. Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol, or upon skipping a meal. Monitor your blood sugar levels regularly while taking it. Before taking this medicine, inform your doctor if you have any kidney, liver, or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

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