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Retatrutide 16mg is being developed to target multiple metabolic conditions, with its primary uses in obesity management, type 2 diabetes, and fatty liver disease.
Retatrutide is an investigational triple hormone receptor agonist (GLP-1, GIP, and glucagon receptors)
Main Uses of Retatrutide
1. Obesity Treatment
Primary target: Adults with obesity (BMI ≥30) or overweight (BMI ≥27) with a weight-related condition.
Effectiveness:
Up to 24.2% body weight loss at the highest tested dose (12 mg) over 48 weeks.
Outperformed semaglutide (Wegovy) and tirzepatide (Zepbound) in trials.
Mechanism:
Appetite suppression
Slowed gastric emptying
Increased energy expenditure
Type 2 Diabetes Management
Improves blood glucose control by:
Enhancing insulin sensitivity
Increasing insulin secretion
Reducing glucagon levels (in a glucose-dependent way)
Massive reductions in liver fat (up to 82.4% in some patients)
Helps improve:
Liver enzyme profiles (ALT, AST)
Hepatic insulin resistance
SKYBLUE INTERNATIONAL
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Weight reduction
Improved insulin sensitivity
Hormonal balancing
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Retatrutide (10mg : - Obesity and Overweight Management
Retatrutide has demonstrated significant efficacy in promoting weight loss. In clinical trials, participants have achieved up to 24.2% weight loss over 48 weeks, outperforming existing treatments like semaglutide and tirzepatide.
Form: Subcutaneous injection (once weekly)
Dose Titration: To reduce side effects (especially GI issues), dosing typically starts low and increases over time.
What Is Retatrutide Used For?
Retatrutide is being developed to target multiple metabolic conditions, with its primary uses in obesity management, type 2 diabetes, and fatty liver disease.
Retatrutide activates the GIP, GLP-1 and glucagon receptors that are involved with controlling hunger and satiety, allowing people to feel fuller after eating for longer. This helps to regulate blood sugar levels, leading to weight loss.
Non-Alcoholic Fatty Liver Disease (NAFLD)
Retatrutide has led to significant reductions in liver fat in patients with metabolic dysfunction-associated steatotic liver disease (MASLD), with reductions up to 82.4% observed in clinical trials.
Target Population
Adults with obesity (BMI ≥30) or overweight (BMI ≥27) with comorbidities (e.g., type 2 diabetes, hypertension)
Adults with type 2 diabetes, especially those who need better weight and glucose control
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Retatrutide is an investigational drug still in clinical trials and has not yet been approved by the FDA for general use. However, based on Phase 2 clinical trials.
Skyblue International leading exporter of Ledifos Ledipasvir (90mg) + Sofosbuvir (400mg) USA FAST DELIVERY
Skyblue International leading exporter of Ledifos Ledipasvir (90mg) + Sofosbuvir (400mg)WE EXPORT IN, KioBedok,Bishan,Bukit Batok,Bukit Merah, Bukit Panjang,Choa Chu Kang, Clementi,Geylang,Hougang, Jurong East, Jurong West, Kallang, Marine Parade, Queenstown ,Sengkang, Simei ,Tampines,. Toa Payoh,Woodlands, Yishun.
Use for:- To treat chronic Hepatitis C
PRICE - $98
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Skyblue International leading exporter of Sofosbuvir 400mg/Ledipasvir 90mg tablets are a combination medication used to treat chronic hepatitis C virus (HCV) infection. This combination inhibits HCV replication, offering high cure rates across multiple genotypes. It's prescribed for adults, helping to improve liver function and reduce the risk of complications like cirrhosis and liver failure.
Uses: Ledifos 90mg/400mg Tablet is a combination of two antiviral medicines. This prescription medicine is used in the treatment of chronic hepatitis C virus (HCV) infection. It fights against the viruses to resolve the infection. Ledifos 90mg/400mg Tablet should be taken in the prescribed dose and duration.
DOSES:- For hepatitis C virus infection: Adults—1 tablet once a day, taken for 12 or 24 weeks.
Menopace capsules are used to manage the symptoms of menopause, including hot flashes, night sweats, and mood swings.
What is the use of benefit Tablet?
Benefit Tablet | Uses, Side Effects, Price | Apollo Pharmacy
Benefit tablets pack a punch with essential vitamins and minerals, including Zinc (immunity), Chromium (blood sugar support), and Selenium (cell health). This potent combo can address deficiencies and potentially boost your energy levels for overall well-being.
What is the success rate of ledipasvir sofosbuvir?
The rates of sustained virologic response were 99% (95% confidence interval [CI], 96 to 100) in the group that received 12 weeks of ledipasvir–sofosbuvir.
Ledipasvir (90mg) + Sofosbuvir (400mg) Ledifos USA FAST DELIVERY| Doses, In India, large demand for them and the high cost of bringing them to market. Developing a new drug, testing it in clinical trials, and marketing it can cost pharmaceutical companies nearly $900 million.
What is the first line treatment for HCV?
Hepatitis C is treated using direct-acting antiviral (DAA) tablets.
How long is the treatment for sofosbuvir and ledipasvir?
Ledipasvir/sofosbuvir (LDV/SOF) combination is administered for 12 to 24 weeks
What are the 5 stages of menopause?
What Are the 5 Stages of Menopause? [Understand the Process]
While every woman's experience is unique, knowing what to expect during each phase can help you prepare for and manage the changes ahead.
What is Menopause? ...
Stage 1: Perimenopause. ...
Stage 2: Early Menopause Transition. ...
Stage 3: Late Menopause Transition. ...
Stage 4: Menopause. ...
Stage 5: Postmenopause.
Can I increase estrogen levels naturally?
How to increase estrogen naturally | UCLA Health
To increase your estrogen levels, consider adding: Boron, a mineral that helps your body absorb testosterone and estrogen. Vitamin B, which helps your body create and use estrogen. Vitamin D, which functions as a hormone in the body and helps with estrogen production
Ledipasvir (90mg) + Sofosbuvir (400mg) Tablets are used for a wide range of purposes, including media consumption, productivity, and education.
Tamoxifen API (Active Pharmaceutical Ingredient) is the pure, bulk powder form of the drug Tamoxifen Citrate, a key selective estrogen receptor modulator (SERM) used mainly to treat and prevent hormone-receptor-positive breast cancers, working as an anti-estrogen by blocking estrogen's effects on cancer cells.
INN / Common name: Tamoxifen citrate
CAS No.: 54965-24-1
Molecular formula: C₂₈H₃₂N₂O·C₆H₈O₇ (citrate salt)
Molecular weight: ~563.64 g/mol
Breast cancer treatment
For estrogen receptor–positive (ER+) breast cancer in pre- and postmenopausal women.
Used in adjuvant therapy (after surgery) or treatment of metastatic disease.
Breast cancer prevention
In high-risk women, tamoxifen reduces the risk of developing breast cancer.
Other estrogen-related conditions (off-label, limited)
Certain gynecomastia cases in men
Fertility treatments (rare off-label use in women to induce ovulation)
Mechanism of action (brief)
Tamoxifen blocks estrogen receptors in breast tissue, preventing estrogen from promoting tumor growth.
In other tissues (bone, uterus), it may act as a partial agonist, producing estrogen-like effects.
Identification
IR spectroscopy: Conforms to reference spectrum
UV / HPLC: Retention time matches certified reference standard
Melting point: Within reference range (~140–144 °C for citrate salt)
Assay (Potency)
Typically 98.0–102.0% (on anhydrous basis)
Generic Name : Mesterolone
Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT). It is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it is not converted into estrogen. Mesterolone demonstrated to have minimal effect on sperm counts and levels of FSH or LH 1,2. Experiments of mesterolone serving as a potential treatment of depression are still undergoing.
Male Hypogonadism/Androgen Deficiency: The primary medical use is to treat low testosterone levels in men due to hypogonadism (a condition where the testes produce little or no hormones). This helps restore normal sexual function, mood, and energy levels.
Male Infertility: It is used to manage male infertility that stems from low androgen levels, as it can improve sperm count and quality in affected men.
INN: Mesterolone
CAS No.: 1424-00-6
Molecular formula: C₂₀H₃₂O₂
Molecular weight: ~304.47 g/mol
Assay (Potency)
Typically 98.0% – 102.0% (on anhydrous basis), depending on pharmacopeial or internal standard
“Turinabol raw API“ refers to the raw active pharmaceutical ingredient (API) of 4-chlorodehydromethyltestosterone (CDMT), an anabolic steroid. Its primary use is in performance enhancement, specifically for muscle growth and athletic performance.
INN / Common name: Chlorodehydromethyltestosterone (Turinabol)
CAS No.: 2446-23-3
Molecular formula: C₂₀H₂₇ClO₂
Molecular weight: ~334.88 g/mol
Performance Enhancement: Turinabol is widely used by athletes and bodybuilders to increase lean muscle mass and strength without significant water retention or estrogenic side effects (like gynecomastia or bloating).
Aesthetic Conditioning: Due to its “dry“ gains and ability to preserve muscle during caloric deficits, it is popular during “cutting“ cycles for aesthetic purposes or for athletes in weight-restricted sports.
Increased Endurance and Recovery: It enhances nitrogen retention and red blood cell production, which improves oxygen delivery to muscles and aids in faster post-training recovery.
Identification
IR spectroscopy: Conforms to reference spectrum
HPLC/UV: Retention time matches certified reference standard
Assay (Potency)
Typically 98.0% – 102.0% (on anhydrous basis), depending on standard applied
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Erectile Dysfunction (ED)
Tadalafil (PDE‑5 inhibitor) relaxes penile blood vessels, improving erections during sexual stimulation
Premature Ejaculation (PE)
Dapoxetine (an SSRI) delays ejaculation, boosting control and satisfaction
Dosage & How to Use:
Available in strengths like 40 mg tadalafil + 60 mg dapoxetine or 60 mg + 30 mg, and 80 mg + 40 mg.
Take 1 tablet orally about 30–60 minutes before sex, not more than once in 24 hours
Can be taken with or without food; avoid alcohol, grapefruit juice, and heavy meals
Additional Benefits
Dual-action therapy—simultaneously tackles ED and PE to improve overall sexual health and satisfaction.
Extended performance window—tadalafil effect may last up to 36 hours, while dapoxetine adds ejaculatory control
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Erectile Dysfunction (ED)
Designed to treat ED by inhibiting PDE‑5, which boosts cGMP levels, relaxing penile blood vessels, and improving erection firmness upon arousal.
Benign Prostatic Hyperplasia (BPH)
Tadalafil may help relax prostate and bladder neck muscles, easing urinary symptoms in BPH.
Pulmonary Arterial Hypertension (PAH)
Though primarily for ED, tadalafil is also used in PAH. Vidalista CT 20 mg may likewise be used under a physician’s direction.
Chewable tablet: Chew thoroughly before swallowing, for faster absorption—typically works within 15–30 minutes, or up to 30–60 minutes
Timing: Take about 30–60 min before sex; effects may last up to 36 hours
Frequency: Only once every 24 hours.
Food and drink: Can be taken with/without food. Avoid high-fat meals, alcohol, grapefruit juice for best effect.
Special note: Some sources erroneously say “place under tongue,” but chew is standard; tablets shouldn’t be swallowed whole.
Vidalista Ct 20 mg is a class PDE5 inhibitor medication which is used to treat erectile dysfunction (ED) or impotence in men.
Most men have the complaint of dissatisfied sexual intercourse due to a softer erection which even leads to breakups.
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Mail :- skyblueinternational033@gmail.com
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Mechanism of Action: Tadalafil, the active ingredient in Vidalista 80mg, belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors.
These medications work by relaxing the muscles in the penis and increasing blood flow, which facilitates an erection when a man is sexually aroused.
Vidalista Black 80 mg (tadalafil) — an ultra-high-dose PDE5 inhibitor designed primarily for erectile dysfunction.
Erectile Dysfunction (ED)
Vidalista Black 80 mg enhances blood flow to the penis during sexual arousal, promoting stronger and longer-lasting erections. It typically takes effect within 30–60 minutes and can remain effective for up to 36 hours.
Dosage & AdministratioN
Recommended intake:
One 80 mg tablet approximately 30–60 minutes before sexual activity.
Maximum frequency: one dose per 24 hours
Food and drink warnings:
Take with water; avoid heavy meals, alcohol, and grapefruit juice around dosing time .
Handling:
Swallow whole—do not crush, chew, or split the tablet.
Active Ingredient Tadalafil 80 mg
Use Erectile Dysfunction—when lower doses fail
How to Take Once daily, 30–60 min before intercourse; swallow whole, with water
Onset & Duration ~30–60 min onset; up to 36 hours of potential effectiveness
Erectile Dysfunction Medicines
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